7 articles
AYUSH-PVK gel
AYUSH-PVK gel is an Ayurvedic vaginal gel developed by the Central Council for Research in Ayurvedic Sciences in India to treat Shweta Pradara, pathological leucorrhoea. PVK stands for Panchavalkala, the stem barks of five trees.
Danicopan
Danicopan (Voydeya, ALXN2040) is an oral complement factor D inhibitor approved in 2024 as add-on to ravulizumab or eculizumab for extravascular hemolysis in adults with paroxysmal nocturnal hemoglobinuria, based on the phase 3 ALPHA trial.
Disufenton
Disufenton sodium (NXY-059, Cerovive, OKN-007) is a nitrone free-radical-trapping drug AstraZeneca developed for acute ischemic stroke; positive SAINT I, negative SAINT II, withdrawn, later studied as OKN-007 for glioblastoma.
Haisco oral complement inhibitor (sipcopan succinate)
HSK39297 (琥珀酸思普可泮片, 优可盼; NXP100) is Haisco's once-daily oral complement factor B inhibitor, approved in China in July 2026 for complement inhibitor-naive PNH adults, with IgAN phase 3 and Nuvectis ex-China licensing.
Sepetaprost
Sepetaprost (ONO-9054, DE-126) is a dual FP/EP3 receptor agonist prodrug eye drop for glaucoma and ocular hypertension; phase 3 ANGEL-J1 showed IOP lowering non-inferior to latanoprost.
Sonlicromanol
Sonlicromanol (KH176) is Khondrion's investigational redox-modulating small molecule, inhibiting mPGES-1 via metabolite KH176m, in phase 3 KHENERFIN trials for m.3243A>G mitochondrial disease (MELAS, MIDD), not approved anywhere.
Tazarotene
Tazarotene (Tazorac, Arazlo) is an acetylenic topical retinoid prodrug converted to tazarotenic acid, selective for RARβ/RARγ, approved since 1997 for plaque psoriasis and acne vulgaris, contraindicated in pregnancy.