7 articles
BEVAC
BEVAC is a recombinant DNA hepatitis B vaccine by Biological E. Limited, India, WHO-prequalified 16 January 2025; 10 µg HBsAg per 0.5 mL paediatric dose, non-inferior to GeneVac-B in a phase IV trial.
Havrix
Havrix (hepatitis A vaccine, inactivated) is GSK's hepatitis A vaccine made from the HM175 strain grown in MRC-5 cells; the first licensed hepatitis A vaccine, FDA-approved in 1995.
HEALIVE
HEALIVE (孩尔来福) is Sinovac's inactivated hepatitis A vaccine using the TZ84 strain in 2BS human diploid cells; China-approved 2002, WHO-prequalified 2017, two-dose pediatric 250 U and adult 500 U schedule.
Heberbiovac HB
Heberbiovac HB: Cuban recombinant hepatitis B vaccine by CIGB, HBsAg in Pichia pastoris, licensed 1990, WHO prequalified 2001, used in over 30 countries.
Live attenuated hepatitis A vaccine (H2 strain)
Chinese single-dose live attenuated hepatitis A vaccine from the H2 strain, developed by Mao Jiangsen's team, licensed 1992, used in China's EPI and India; efficacy 94-100%.
Recombinant hepatitis E vaccine (E. coli)
Recombinant hepatitis E vaccine (E. coli), brand Hecolin (益可宁), HEV 239; the first and only licensed hepatitis E vaccine, an E. coli-expressed ORF2 virus-like particle vaccine developed by Xiamen University and Wantai, licensed in China 2011 with 100% per-protocol phase 3 efficacy.
Twinrix
Twinrix is a combination vaccine against hepatitis A and hepatitis B given to adults, produced by GlaxoSmithKline and first approved in the United States in 2001.