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Depressive disorders

13 articles

Atypical depression

Atypical depression, a major depressive disorder subtype with mood reactivity plus hypersomnia, hyperphagia, leaden paralysis, and rejection sensitivity; MAOI-responsive, immunometabolically distinct from melancholic depression.

Catatonic depression

Catatonic depression: major depressive disorder with catatonic features (DSM-5-TR specifier; ICD-11 catatonia associated with another mental disorder). Mutism, stupor, posturing; treated with lorazepam and ECT.

Depression (mood)

Depression (depressive disorder) is a common mental disorder involving persistent depressed mood or loss of interest for at least two weeks; about 322 million people affected, more common in women, treatable with psychotherapy and antidepressants.

Disruptive mood dysregulation disorder

Disruptive mood dysregulation disorder (DMDD), a DSM-5 depressive disorder added in 2013, involves chronic childhood irritability and frequent severe temper outbursts; created to curb pediatric bipolar misdiagnosis, with 3.3% community prevalence and no FDA-approved medications.

Dysthymia

Dysthymia, now persistent depressive disorder (PDD), is chronic mild depression lasting two years or more; DSM-5-TR dropped the dysthymia label; US past-year prevalence 1.5%, lifetime 2.5%.

Major depressive disorder

Major depressive disorder (MDD, clinical depression): a DSM-5-defined mood disorder of two-week depressive episodes. Formerly melancholia; affects 8.3% of US adults yearly; treated with psychotherapy, antidepressants, ECT, esketamine.

Major depressive episode

Major depressive episode: a period of at least two weeks with depressed mood or anhedonia plus five of nine DSM-5 symptoms causing impairment; basis of major depressive disorder, near-identical in ICD-11.

Postpartum depression

Postpartum depression, also called postnatal depression, is depression starting within 12 months of childbirth that affects about one in eight new mothers and needs treatment.

Premenstrual dysphoric disorder

Premenstrual dysphoric disorder (PMDD), formerly late luteal phase dysphoric disorder, is a severe DSM-5 cyclic mood disorder affecting about 5% of reproductive-aged women, treated first-line with SSRIs.

Seasonal affective disorder

Seasonal affective disorder (SAD), or winter depression, is a recurrent seasonal depression coined by Norman Rosenthal in 1984; winter-pattern symptoms include oversleeping and carbohydrate cravings, treated with 10,000-lux light therapy, CBT-SAD, and bupropion.

Self-hatred

Self-hatred, or self-loathing, is persistent negative feeling toward oneself: inadequacy, guilt, low self-esteem. Studied as hated-self self-criticism; linked to depression; treated with compassion-focused and self-compassion interventions.

Single episode depressive disorder

Single episode depressive disorder is an ICD-11 diagnosis (code 6A70) for a person who has had exactly one depressive episode, with no prior episodes and no history of mania.

SUPEERmood trial

SUPEERmood (SUPEERMood), NCT06398561, is a Mallorca-based randomized trial testing a 6-week nurse-supervised peer-led support program against the COGITO CBT mHealth app for reducing BDI-II depressive symptoms in major depression.