1,953 articles
2024 Laos methanol poisoning
2024 Laos methanol poisoning: November 2024 mass methanol poisoning in Vang Vieng, Laos, from tainted vodka at Nana Backpackers Hostel, killing six foreign tourists (two Australian, British, American, two Danish) and hospitalizing about 11 others.
2026 Ebola epidemic
2026 Ebola epidemic: Bundibugyo virus disease outbreak beginning in Ituri, DRC, April 2026; DRC's 17th Ebola outbreak, spread to Uganda, France, Germany; WHO PHEIC 17 May 2026; second largest Ebola outbreak on record, ~9,500 cases, CFR ~48%.
2026 Kent meningitis outbreak
2026 Kent meningitis outbreak: MenB invasive meningococcal disease cluster in Canterbury, England, March 2026, linked to Club Chemistry and the University of Kent; 21 confirmed cases, 2 deaths, ST-485 P1.12-1,16-183 strain, antibiotics and targeted vaccination response.
3D study
3D study (Design, Develop, Discover; Découvrir, Développer, Devenir), a Quebec pregnancy and birth cohort of 2,366 women recruited 2010–2012 by IRNPQEO, following mother–father–child triads to age 2 with biospecimens and neurodevelopmental data.
56 Dean Street
56 Dean Street (56DS) is a free NHS sexual health and HIV clinic in Soho, London, run by Chelsea and Westminster Trust since 2009, with rapid-testing sister site Dean Street Express (2014), TransPlus gender services, and HIV diagnoses down over 80% from the 2015 peak.
A1chieve® study
A1chieve (A1chieve® study) was a Novo Nordisk-sponsored 24-week observational study of 66,726 people with type 2 diabetes starting insulin detemir, biphasic insulin aspart 30, or insulin aspart across 28 non-Western and other countries.
A2ALL-2 study
A2ALL-2 (Adult-to-Adult Living Donor Liver Transplantation Cohort Study 2), NCT01619475, was the second NIDDK-funded cycle of the A2ALL consortium: nine North American transplant centers with a University of Michigan data center, studying donor psychosocial, financial, and recipient graft outcomes of living liver donation, 2011–2014.
AAIMASP trial
AAIMASP (Get Going, NCT02635477) was an American College of Cardiology fellows-led multicenter randomized trial testing an adaptive accelerometer step-counter bracelet versus a monitor-only device to raise daily steps in frail adults 70+ in the 30 days after cardiovascular hospitalization; registry status unknown, no results posted.
Aarhus University Hospital
Aarhus University Hospital (Aarhus Universitetshospital, AUH) is a 528,000 m² university hospital in Skejby, Aarhus, Denmark, formed by the 2011 merger of Skejby and Aarhus Sygehus, with 840 beds and about 9,300 full-time staff.
Aarogya Setu (आरोग्य सेतु)
Aarogya Setu (आरोग्य सेतु) is India's government COVID-19 contact tracing app launched 2 April 2020, using Bluetooth and GPS, with over 114 million users by May 2020, open-sourced under Apache 2.0, criticized for privacy issues, and repurposed in 2026 as Aarogya Setu 2.0, a National Health Authority personal health record app.
ABCD study
ABCD study (NCT05450016), Assessment of the Breast Cosmesis Using Deep Neural Networks, a Tata Memorial Centre observational study classifying post-treatment breast cosmesis from photographs using AI, targeting 720 participants; distinct from ABCD RT, ABCD-Trial (ALS), and the ABCD brain study.
Abortion in Canada
Abortion in Canada: legal medical procedure since the 1988 R. v. Morgentaler Supreme Court decision struck down Criminal Code section 251; no federal abortion law; medical (Mifegymiso) and surgical abortion insured under provincial plans, with access barriers and federal Sexual and Reproductive Health Fund support.
Abortion in the Republic of Ireland
Abortion in the Republic of Ireland, also called the Repeal of the Eighth Amendment, has been legal under the Health (Regulation of Termination of Pregnancy) Act 2018 since January 2019: on request up to 12 weeks, and later only for risk to life, serious health harm, or fatal fetal anomaly.
Abortion in the United Kingdom
Abortion in the United Kingdom: lawful in England, Scotland, and Wales under the Abortion Act 1967 with a two-doctor requirement and 24-week limit; decriminalised in Northern Ireland in 2019; 277,970 abortions in England and Wales in 2023.
Abortion statistics in the United States
US abortion statistics from CDC surveillance, Guttmacher Institute surveys, and #WeCount: about 1.03–1.14 million abortions annually post-Dobbs, medication abortion 63%, telehealth 27%, with state-level divergence after bans.
Academic detailing
Academic detailing is educational outreach in which trained professionals, usually pharmacists or physicians, visit clinicians to deliver evidence-based messages that change prescribing, modeled on pharmaceutical sales visits.
ACCELERATE study
ACCELERATE (NCT02817997) is an international, patient-powered natural history registry for Castleman disease, launched in 2016 by the University of Pennsylvania and the Castleman Disease Collaborative Network, distinct from the pediatric oncology platform of the same name.
Accident
Accident: an unpremeditated event causing recognizable damage (WHO definition). Public health now prefers "injury"; 4.4 million injury deaths yearly, 90% in low- and middle-income countries, largely preventable via energy-control strategies.
Accident Insurance
Accident insurance pays fixed benefits for death, dismemberment, disability, or medical costs from accidental injury. Commercial personal accident cover began in railway-age England (1848-1849); Germany's 1884 Bismarck law founded statutory accident insurance.
Accident Prevention
Accident prevention, also called injury prevention or safety promotion, is the organized effort to reduce accidental injuries through hazard elimination, engineering controls, regulation, and education, spanning workplace, road, home, and community safety.
ACIOS study
ACIOS (African Critical Illness Outcomes Study), NCT06051526, a Lancet-published 2023 point prevalence study of 19,872 adults in 180 hospitals across 22 African nations: 12.5% critically ill, 20.7% 7-day mortality, most in general wards with unmet essential care.
ACTIBATE trial
ACTIBATE (Activating Brown Adipose Tissue Through Exercise), NCT02365129, a University of Granada randomized controlled trial in 145 young sedentary adults testing 24 weeks of moderate or vigorous endurance-plus-resistance training; it found no change in brown adipose tissue volume or activity but improved fitness and reduced adiposity.
ActiveBrains trial
ActiveBrains trial: 20-week randomized clinical trial at the University of Granada (NCT02295072) in 109 children aged 8-11 with overweight/obesity; supervised aerobic plus resistance exercise improved crystallized and total intelligence and cognitive flexibility, with null effects on inhibition, working memory, and hippocampal volume.
Acute toxicity
Acute toxicity: adverse effects from a single dose or doses within 24 hours, by oral, dermal, or inhalation route, quantified by LD50/LC50, used for chemical classification and labelling.
ADAGES study
ADAGES (African Descent and Glaucoma Evaluation Study), NCT00221923, is an NEI-funded prospective cohort at UCSD, NYEE, and UAB comparing glaucoma onset, structure, and progression in African versus European descent participants.
Adaptive clinical trial
An adaptive clinical trial is a trial design allowing prospectively planned modifications, such as sample size reassessment or dropping inferior arms, based on interim data, with adaptations pre-specified before the trial starts.
Adaptive randomization
Adaptive randomization is a clinical trial randomization method in which assignment probabilities change as data arrive, either balancing treatment groups on prognostic factors or shifting patients toward treatments performing better so far.
Addenbrooke's Hospital
Addenbrooke's Hospital, Cambridge teaching hospital run by Cambridge University Hospitals NHS Foundation Trust; founded from John Addenbrooke's 1719 bequest, opened 1766 on Trumpington Street, now on the Cambridge Biomedical Campus, Hills Road.
Admixture mapping
Admixture mapping is a genetic association method, proposed by Paul McKeigue in 1998, that finds disease variants in admixed populations by testing local ancestry against phenotype.
Advance healthcare directive
Advance healthcare directive: written instruction or proxy appointment (living will, durable power of attorney, ADRT) governing medical care during incapacity; covers CPR, ventilation, nutrition; US completion about 36.7% of adults.