25,729 articles
Miglustat
Miglustat (N-butyldeoxynojirimycin, Zavesca) is an oral glucosylceramide synthase inhibitor, a substrate reduction therapy for type 1 Gaucher disease and Niemann-Pick type C neurological manifestations, and part of Pompe combination therapy.
Migraine
Migraine: a primary headache disorder of recurrent one-sided throbbing attacks with nausea and light sensitivity, classified in ICHD-3; global prevalence about 14%, treated with triptans, gepants, and CGRP preventives.
Migraine with aura
Migraine with aura (classic migraine, ICHD-3 code 1.2): recurrent attacks of gradually spreading, fully reversible visual, sensory, or other neurological symptoms lasting 5-60 minutes, usually followed by headache; mechanism linked to cortical spreading depression; carries elevated stroke risk.
Migraine without aura
Migraine without aura (common migraine, ICHD-3 1.1, ICD-11 8A80.0) is the most common migraine form, about 70-75% of cases: recurrent 4-72 hour unilateral pulsating headache with nausea or photophobia/phonophobia, no aura.
Migraine-induced stroke
Migraine-induced stroke, or migrainous infarction (ICD-11 8B22.9), is a rare ischemic stroke during a migraine with aura attack when aura lasts over 60 minutes; mostly posterior circulation, young women, favorable prognosis.
Mike O'Hearn
Mike O'Hearn, American bodybuilder, fitness model, and TV personality; four-time Mr. Natural Universe, Titan on NBC's 2008 American Gladiators, 500+ magazine covers; his lifetime-natural claim is widely disputed.
Milademetan
Milademetan (DS-3032b, RAIN-32) is an oral spiro-oxindole MDM2-p53 interaction inhibitor from Daiichi Sankyo licensed to Rain Therapeutics; its phase III MANTRA trial in dedifferentiated liposarcoma failed, and it remains unapproved.
MILAN trial
MILAN (NCT05450328) is a multicenter double-blind randomized trial at the Montreal Heart Institute testing inhaled epoprostenol 60 mcg plus milrinone 4 mg versus placebo before cardiopulmonary bypass to prevent difficult bypass weaning in 142 cardiac surgery patients.
Milap C. Nahata
Milap C. Nahata is an American pharmacist-scientist at Ohio State whose research made medications safer and better dosed for children, earning the 2024 Remington Honor Medal.
Mild hyperemesis gravidarum
Mild hyperemesis gravidarum (ICD-11 JA60.0; ICD-10-CM O21.0) is pregnancy vomiting responsive to dietary modification and antiemetics, starting before the end of the 22nd week, distinguished from HG with metabolic disturbance (JA60.1) and managed in community care.
Mild hyperphenylalaninemia
Mild hyperphenylalaninemia (mild HPA), also known as non-PKU hyperphenylalaninemia or MHP, is the mildest form of phenylalanine hydroxylase deficiency, an inherited metabolic disorder with blood phenylalanine of 120 to 600 micromol/L.
Mild hyperthermia
Mild hyperthermia is a cancer treatment that heats tumors to about 39–45 °C, sensitizing cells to radiotherapy and chemotherapy, unlike ablation, which destroys tissue above 50 °C.
Mild intellectual disability
Mild intellectual disability: a developmental disability with IQ below about 70, adaptive behavior deficits, and onset before adulthood; prevalence 0.7–1.3%, often grouped with borderline intellectual functioning (IQ 71–84) as MBID.
Mild neurocognitive disorder
Mild neurocognitive disorder (mild NCD, DSM-5 2013; ICD-11 6D71) is a modest, measurable cognitive decline beyond normal aging, roughly matching mild cognitive impairment, with independence preserved and ten etiologic specifiers.
Mild personality disorder
Mild personality disorder (ICD-11 6D10.0) is the lowest severity level of personality disorder in ICD-11, above personality difficulty, aligned with DSM-5 AMPD level 2 moderate impairment, typically with one trait qualifier.
Mild to moderate pre-eclampsia
Mild to moderate pre-eclampsia (ICD-11 JA24.0), pre-eclampsia without severe features. Managed with surveillance, labetalol or nifedipine, target BP 135/85 mmHg, and birth at 34-37+ weeks; WHO advises induction at term.
MILD trial
MILD (Multicentric Italian Lung Detection) trial, Italian randomized trial begun 2005 comparing annual vs biennial low-dose CT lung cancer screening with no screening in 4,099 heavy smokers; reported 39% lung cancer mortality reduction with prolonged screening.
Mild vision impairment
Mild vision impairment, mildest WHO/ICD-11 grade of distance vision impairment: presenting visual acuity worse than 6/12 to 6/18 (CDC: 20/32 to >20/80) in the better eye, mostly uncorrected refractive error.
Miliaria
Miliaria (heat rash, prickly heat, sweat rash) is a common rash from blocked eccrine sweat ducts, with types crystallina, rubra, pustulosa, and profunda classified by duct obstruction depth; common in neonates and hot, humid climates.
Miliary tuberculosis
Miliary tuberculosis, also known as disseminated tuberculosis, is a severe form of tuberculosis in which bacteria spread through the bloodstream to many organs; untreated, it is fatal.
Military Hospitals
Military hospitals treat service members and usually dependents, from ancient rear-tent care to modern MTFs; the US system runs 700+ facilities, nine Defense Health Networks, and field hospitals for 9.5 million beneficiaries.
Military Medical Academy
Military Medical Academy (VMA, Војномедицинска академија), Belgrade: Serbia's central military hospital and medical school, founded 1844 as Central Military Hospital, Medical Faculty of the University of Defence since 2011.
Military medicine
Military medicine is the branch of medicine treating battlefield casualties from point of injury through evacuation, surgery, and rehabilitation, and maintaining the health of armed forces.
Military sexual trauma
Military sexual trauma (MST) is the VA term for sexual assault or sexual harassment during military service. About 1 in 3 women and 1 in 50 men screened in VA report it; free MST-related care and disability compensation are available.
Miller Fisher syndrome
Miller Fisher syndrome (MFS, Fisher syndrome) is a rare variant of Guillain-Barré syndrome defined by the triad of ophthalmoplegia, ataxia, and areflexia, linked to anti-GQ1b antibodies and usually self-limiting recovery.
Mills syndrome
Mills syndrome is a rare, acquired motor neuron disease marked by slowly progressive spastic hemiparesis on one side of the body with no sensory loss, first described in 1900.
Milrinone
Milrinone, formerly sold as Primacor, is a type III phosphodiesterase inhibitor given by intravenous infusion to treat severe heart failure and low cardiac output, including as a bridge to heart transplantation.
Milroy disease
Milroy disease (hereditary lymphedema type I, Nonne-Milroy lymphedema): autosomal dominant congenital lower-limb lymphedema, usually from FLT4/VEGFR3 mutations at 5q35.3, named after W. F. Milroy's 1892 family report.
Milton Allen Northrup
Milton Allen Northrup, known as M. Allen Northrup, is an American bioengineer and entrepreneur who co-founded the diagnostics company Cepheid and first demonstrated PCR in a micromachined silicon chip.
Milvexian
Milvexian (BMS-986177, JNJ-70033093) is an investigational oral, small-molecule, reversible direct factor XIa inhibitor from Bristol Myers Squibb and Janssen; it prevented VTE after knee arthroplasty in phase 2 but failed in the phase 3 LIBREXIA ACS trial.