25,729 articles
STT3A-CDG
STT3A-CDG (CDG type Iw, OMIM 615596) is an ultra-rare congenital disorder of N-linked glycosylation from STT3A gene mutations, causing developmental delay, intellectual disability, failure to thrive, hypotonia, and seizures; recessive and dominant forms exist.
STT3B-CDG
STT3B-CDG (CDG-Ix, OMIM 615597) is a rare autosomal recessive N-glycosylation disorder caused by STT3B mutations, with hypotonia, developmental delay, seizures, and near-normal transferrin, so exome sequencing is often needed.
STTEPP trial
STTEPP (NCT05603702) is a phase 1 Indiana University dose-escalation trial of lacosamide added to opioids in painful chronic pancreatitis, testing safety, tolerability, and dose-limiting toxicity against opioid-induced hyperalgesia.
Stunted growth
Stunted growth, also called growth retardation or child stunting, is impaired growth in children from chronic undernutrition and repeated infection; in 2024 an estimated 150.2 million children under 5 were stunted.
Sturge–Weber syndrome
Sturge–Weber syndrome, also called encephalotrigeminal angiomatosis, is a rare congenital neurocutaneous disorder featuring a facial port-wine birthmark, leptomeningeal angioma, and glaucoma, caused by a GNAQ mutation.
Stuttering
Stuttering (stammering) is a neurodevelopmental speech disorder of repetitions, prolongations, and blocks, affecting over 5% of preschool children, chronic in about 1% of adults, with genetic and neurogenic forms.
Stüve-Wiedemann syndrome
Stüve-Wiedemann syndrome is a rare autosomal recessive skeletal dysplasia, first described in 1971, causing bowed long bones, camptodactyly, hyperthermia, and respiratory distress that is usually fatal in infancy.
STXBP1-related developmental and epileptic encephalopathy
STXBP1-related developmental and epileptic encephalopathy (STXBP1-DEE, EIEE4), also called STXBP1 encephalopathy, is a rare autosomal dominant disorder caused by de novo STXBP1/Munc18-1 variants, causing early-onset refractory epilepsy, intellectual disability, movement disorders, and autism features.
Stye
Stye (hordeolum): a painful bacterial abscess of an eyelid gland, usually Staphylococcus aureus; external (Zeis/Moll glands) or internal (meibomian). Treated with warm compresses; distinct from a painless chalazion.
STYJOBS study
STYJOBS (STyrian Juvenile OBesity Study), also STYJOBS/EDECTA, NCT00482924, is a prospective observational cohort on early metabolic and vascular changes in obesity, run since 2003 by Harald Mangge at the Medical University of Graz with 1,325 subjects and a biobank.
SU-DHL-4
SU-DHL-4 (DHL4), Stanford University-Diffuse Histiocytic Lymphoma-4, a human GCB-type diffuse large B-cell lymphoma cell line from a 38-year-old male's peritoneal effusion, carrying IGH-BCL2 fusion, EZH2 Y641S/Y661N, TP53 R273C; ATCC CRL-2957, DSMZ ACC-495.
Subacromial bursitis
Subacromial bursitis, part of subacromial pain syndrome (impingement, rotator cuff tendinopathy), is inflammation of the subacromial-subdeltoid bursa causing painful arc shoulder pain; treated nonoperatively, steroid injections give short-term relief, surgery shows no benefit.
Subacute Care
Subacute care, also called post-acute care, is skilled medical and nursing care for patients past the acute illness phase but needing more than long-term care, typically one to two therapy hours daily in skilled nursing facilities.
Subacute combined degeneration of spinal cord
Subacute combined degeneration (SACD, SCD) is vitamin B12 deficiency myelopathy of the dorsal and lateral spinal cord columns, causing sensory loss and spasticity; increasingly caused by nitrous oxide inactivation of B12.
Subacute cutaneous lupus erythematosus
Subacute cutaneous lupus erythematosus (SCLE) is a photosensitive, non-scarring subtype of cutaneous lupus with annular or papulosquamous lesions, strong anti-Ro/SSA association, 20-40% drug-induced cases, and systemic progression risk.
Subacute inflammatory demyelinating polyneuropathy
Subacute inflammatory demyelinating polyneuropathy (SIDP, ORPHA:206594) is a rare immune-mediated neuropathy intermediate between GBS and CIDP, with symmetric weakness and elevated CSF protein peaking over 4 to 8 weeks.
Subacute osteomyelitis
Subacute osteomyelitis, or Brodie's abscess, is a low-grade bone infection with insidious onset, no fever, pain for weeks to months, Staphylococcus aureus most often, and metaphyseal lytic lesions in children.
Subacute sclerosing panencephalitis
Subacute sclerosing panencephalitis (SSPE), formerly Dawson's disease, is a rare, fatal progressive brain disease caused by persistent defective measles virus infection, appearing 4-10 years after measles, prevented only by vaccination.
Subacute thyroiditis
Subacute (de Quervain) thyroiditis: self-limited, painful, post-viral thyroid inflammation with thyrotoxic then hypothyroid phases, low RAIU, high ESR, and recovery in most patients.
Subarachnoid hemorrhage
Subarachnoid hemorrhage (SAH), bleeding into the subarachnoid space around the brain, usually from a ruptured cerebral aneurysm; presents as thunderclap headache, diagnosed by CT, treated by clipping or coiling.
Subbian Panayampalli
Subbian Panayampalli, also known as Panayampalli Subbian Satheshkumar, is a CDC scientist who leads poxvirus and rabies diagnostics research and received a 2019 PECASE award.
Subchondral Arthroplasty
Subchondral arthroplasty (Arthroplasty, Subchondral, MeSH D054544) is the group of marrow-stimulation surgeries, abrasion arthroplasty, subchondral drilling, and microfracture, that perforate subchondral bone to fill cartilage defects with fibrocartilage.
Subclavian artery
Subclavian artery: paired artery of the upper thorax and neck; left arises from the aortic arch, right from the brachiocephalic trunk; three scalene-defined parts; becomes the axillary artery at the first rib.
Subclavian steal syndrome
Subclavian steal syndrome: symptoms from reversed vertebral artery flow caused by proximal subclavian artery stenosis, also called coronary subclavian steal after LIMA grafting; mostly left-sided, atherosclerotic, usually benign, treated conservatively with stenting or bypass for selected symptomatic cases.
Subconjunctival injection
A subconjunctival injection places medication into the space between the conjunctiva and sclera of the eye, delivering a drug depot that diffuses through the sclera to ocular tissues.
Subcorneal pustular dermatosis
Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) is a rare chronic neutrophilic skin disease with sterile subcorneal pustules on the trunk and flexures; dapsone is first-line treatment.
Subcortical band heterotopia
Subcortical band heterotopia (SBH, double cortex syndrome, subcortical laminar heterotopia): a neuronal migration disorder forming a gray-matter band beneath the cortex, mainly in females, caused by DCX or PAFAH1B1 mutations and part of the lissencephaly spectrum.
Subcostal transversus abdominis plane block
The subcostal transversus abdominis plane (SCTAP) block is an anesthesia technique that injects local anesthetic beneath the costal margin to numb the upper abdominal wall, used for surgery above the umbilicus such as cholecystectomy.
Subcutaneous dirofilariasis
Subcutaneous dirofilariasis (ICD-11 1F66.4) is a zoonotic mosquito-borne filarial infection of humans, mainly by Dirofilaria repens in Europe, Asia, and Africa, causing migratory or nodular subcutaneous and ocular lesions treated by surgical excision.
Subcutaneous emphysema
Subcutaneous emphysema (surgical emphysema) is air trapped under the skin, causing swelling and crepitus. Causes include trauma, pneumothorax, infection, and dental, ENT, or thoracic procedures; usually self-limiting, resolving in 10-14 days.