25,729 articles
Surgical treatment of ingrown toenails
Surgical treatment of ingrown toenails (onychocryptosis): partial nail avulsion, phenol or TCA chemical matricectomy, Winograd wedge resection, and Vandenbos procedures; phenolization cuts recurrence versus avulsion alone, while a 2026 meta-analysis favors minimally invasive surgery.
Surgical ventricular reconstruction
Surgical ventricular reconstruction (SVR), most often the Dor procedure, is a cardiac operation that reshapes the scarred left ventricle after a heart attack, usually combined with coronary bypass grafting.
Surgically-Created Structures
Surgically-Created Structures is a Medical Subject Headings descriptor covering organs surgically formed from adjacent tissue to replace tissue that is diseased or surgically removed, distinct from prostheses and implants.
Suriclone
Suriclone (RP 31,264; Suril, Celexane) is a cyclopyrrolone anxiolytic, chemically unrelated to benzodiazepines, that binds benzodiazepine receptor sites allosterically with subnanomolar affinity and was trialed in generalized anxiety disorder.
SURMOUNT-1 trial
SURMOUNT-1 was a phase 3 trial funded by Eli Lilly testing weekly tirzepatide for weight loss in adults with obesity, showing reductions up to 20.9% and a 94% lower risk of progression to type 2 diabetes.
Surotomycin
Surotomycin (CB-183,315), a daptomycin-analog cyclic lipopeptide antibiotic for Clostridium difficile infection; membrane-disrupting, minimally absorbed; Phase 3 trials showed no benefit over vancomycin and development was discontinued.
SURTAVI trial
SURTAVI (Surgical Replacement and Transcatheter Aortic Valve Implantation), NCT01586910: Medtronic-funded randomized trial showing self-expanding CoreValve/Evolut R TAVR noninferior to surgery at 2 and 5 years in 1,746 intermediate-risk aortic stenosis patients.
Surufatinib
Surufatinib (HMPL-012, Sulanda) is HUTCHMED's oral kinase inhibitor of VEGFR1-3, FGFR1, and CSF-1R, approved in China (2020, 2021) for extrapancreatic and pancreatic neuroendocrine tumors based on the SANET-ep and SANET-p phase 3 trials; not FDA or EMA approved.
Surveillance colonoscopy
Surveillance colonoscopy is the repeated colonoscopic examination at set intervals of people at increased risk of colorectal cancer, including those after polyp removal, with IBD, or with hereditary syndromes.
Surveillance culture
A surveillance culture is a microbiology test that detects colonization by multidrug-resistant organisms such as MRSA, VRE, and Candida auris in patients without infection signs, guiding isolation and decolonization.
SURVIVE trial
SURVIVE (NCT05163080) is MimiVax and Roswell Park's phase 2b randomized placebo-controlled trial of the survivin vaccine SurVaxM plus temozolomide in newly diagnosed glioblastoma; median OS 22.8 vs 20.3 months (p=0.076), with significance only in patients 65 and under.
Survodutide
Survodutide (BI 456906) is an investigational once-weekly injectable drug by Boehringer Ingelheim that acts on glucagon and GLP-1 receptors for obesity, type 2 diabetes, and MASH.
Surzebiclimab
Surzebiclimab (BGB-A425), BeiGene's humanized IgG1 anti-TIM-3 monoclonal antibody, blocks TIM-3 ligands PtdSer and galectin-9; tested with tislelizumab and alcestobart in Phase 1/2 trial NCT03744468 for advanced solid tumors, NSCLC and HNSCC.
Susac syndrome
Susac syndrome is a rare autoimmune disease that blocks small vessels in the brain, retina, and inner ear, causing encephalopathy, vision loss, and hearing loss.
Susan B. Hassmiller
Susan B. Hassmiller is an American nurse and health policy leader who spent nearly 25 years as the Robert Wood Johnson Foundation's senior adviser for nursing.
Susan G. Komen for the Cure
Susan G. Komen for the Cure, the trade name of the Susan G. Komen Breast Cancer Foundation, is a Dallas-based breast cancer nonprofit founded in 1982 by Nancy Brinker, known for Race for the Cure, the pink ribbon, and the 2012 Planned Parenthood funding reversal.
Susan Hajaran Tousi
Susan Hajaran Tousi is an American bioengineering executive elected to the National Academy of Engineering in 2018, known for leading genome-sequencing products at Illumina before becoming CEO of DELFI Diagnostics.
Susan Monarez
Susan Coller Monarez, American microbiologist and immunologist, first Senate-confirmed CDC director; confirmed July 29, 2025 (51-47), sworn in July 31, fired August 27, 2025 after 29 days in a vaccine-policy clash with HHS Secretary Robert F. Kennedy Jr.
Susan Powter
Susan Powter is an Australian-born American fitness personality whose 1993 infomercial and book Stop the Insanity! made her a defining fitness celebrity of the 1990s.
Susceptibility to viral and mycobacterial infections due to STAT1 deficiency
STAT1 deficiency (ORPHA391311, OMIM 613796) is a rare autosomal recessive primary immunodeficiency impairing type I and type II interferon signaling, causing early-onset severe mycobacterial and herpesvirus infections; complete forms are fatal without HSCT.
Susceptibility weighted imaging
Susceptibility weighted imaging (SWI) is an MRI technique using phase images to highlight blood, iron, and calcium, developed from 1997 venography work by Reichenbach and Haacke.
Sushruta
Sushruta is the name given to the Suśrutasaṃhitā, a foundational Sanskrit Ayurvedic treatise on surgery often called the Father of Surgery, though recent scholarship treats it as a multi-author work.
Suspensory fixation
Suspensory fixation is a surgical technique that anchors a ligament graft to the far cortex with a button and suture loop, popular in ACL reconstruction.
Suspensory ligament of ovary
Suspensory ligament of ovary (infundibulopelvic ligament, ligamentum suspensorium ovarii): a peritoneal fold from ovary to pelvic sidewall carrying the ovarian vessels, nerves, and lymphatics; not a true ligament, distinct from the proper ovarian ligament.
Suspiciousness
Suspiciousness (ICD-11 MB26.9) is the tendency to view individuals or agencies as having harmful intents, a thought-content symptom ranging from ordinary trait to paranoia-spectrum clinical feature, distinct from hypervigilance and persecutory delusion.
Susrutasamhita
The Susrutasamhita (Suśrutasaṃhitā, सुश्रुतसंहिता) is a Sanskrit Ayurvedic compendium centered on surgery, describing hundreds of procedures and instruments, and taking its received form by about the fourth or fifth century CE.
Sustained ventricular tachycardia
Sustained ventricular tachycardia (持続性心室頻拍), ICD-11 BC71.02, is ventricular tachycardia lasting over 30 seconds or causing hemodynamic instability, usually reentry-based in structural heart disease, treated with cardioversion, ICDs, and ablation.
SUSTAIN™ 2 trial
SUSTAIN 2 was a 56-week phase 3a trial comparing once-weekly subcutaneous semaglutide (0.5 mg, 1.0 mg) with once-daily sitagliptin 100 mg in 1231 adults with type 2 diabetes on metformin or thiazolidinediones; semaglutide was superior for HbA1c and weight.
SUSTAIN™ 3 trial
The SUSTAIN 3 trial was a Novo Nordisk phase 3 trial in which once-weekly semaglutide 1.0 mg beat exenatide ER in 813 adults with type 2 diabetes.
SUSTAIN™ 6 trial
SUSTAIN 6 (NCT01720446) was the preapproval cardiovascular outcomes trial of once-weekly subcutaneous semaglutide 0.5/1.0 mg versus placebo in 3,297 type 2 diabetes patients at high cardiovascular risk; MACE HR 0.74 confirmed noninferiority, with higher retinopathy complications.