Human health and medicine

Uterine myomectomy

Uterine myomectomy, also called fibroid removal surgery, surgically removes uterine leiomyomas while preserving the uterus. Approaches include open, laparoscopic, robotic, and hysteroscopic; it preserves fertility but carries recurrence up to 60% at five years.

Uterine prolapse

Uterine prolapse, descent of the uterus toward or past the vaginal opening, a form of pelvic organ prolapse. Documented since the Kahun papyrus (ca. 1835 BCE); treated with pessaries or surgery, including hysterectomy or uterus-preserving repair.

Uterine transplantation

Uterine transplantation, also called uterus transplantation or UTx, implants a donor uterus into a woman with absolute uterine factor infertility so she can carry a pregnancy.

Oct 20, 2026

Uterovaginal prolapse

Uterovaginal prolapse (ICD-11 GC40.3, ICD-10 N81.3) is descent of the uterus, cervix, and upper vagina, a central-compartment pelvic organ prolapse managed with pessaries or hysterectomy, hysteropexy, or mesh sacro-hysteropexy.

Uterus didelphys

Didelphys uterus (uterus didelphys, double uterus) is a congenital Müllerian fusion defect with two separate uterine cavities, usually two cervices and a longitudinal vaginal septum; about 5% of uterine anomalies, associated with renal agenesis, preterm birth and caesarean delivery.

Uterus transplantation

Uterus transplantation is a surgical procedure that transfers a donor uterus into a woman with absolute uterine factor infertility; the first live birth was in 2014.

Utidelone

Utidelone (优替德隆, UTD1), an epothilone analogue microtubule stabilizer by Beijing Biostar, approved in China March 2021 with capecitabine for metastatic breast cancer; phase III PFS 8.44 vs 4.27 months, main toxicity peripheral neuropathy.

Utilization Review

Utilization review is the evaluation of patient care, especially in Medicare and Medicaid, to determine whether it is appropriate, medically necessary, and consistent with accepted standards.

Utomilumab

Utomilumab (PF-05082566), Pfizer's fully human IgG2 agonist antibody against 4-1BB (CD137), binds CRD3-4, blocks 4-1BBL, is a weak FcγR-dependent agonist, was safer than urelumab but had limited efficacy, and development was discontinued.

Utreglutide

Utreglutide (GL0034) is Sun Pharma's investigational once-weekly, G protein-biased GLP-1 receptor agonist for type 2 diabetes and obesity, structurally related to semaglutide, in phase 2 trials, unapproved.

Utricle (ear)

Utricle (ear): otolith organ of the vestibular labyrinth, with the saccule; its horizontal macula, striola, and otoconial membrane sense horizontal linear acceleration and head tilt, tested clinically by oVEMP and SVV.

UV-B lamps

UV-B lamps emit 280–320 nm ultraviolet B for phototherapy; narrowband (311–313 nm, Philips TL01) and broadband types treat psoriasis, eczema, and vitiligo, with dosing by minimal erythema dose.

UV-sensitive syndrome

UV-sensitive syndrome (UVsS, UVSS), a rare autosomal recessive photodermatosis from ERCC6, ERCC8, or UVSSA mutations causing defective transcription-coupled nucleotide excision repair; sun sensitivity and dyspigmentation without skin cancer risk or neurologic disease.

UVB phototherapy

UVB phototherapy is a dermatological treatment exposing the skin to ultraviolet B light to treat psoriasis, vitiligo, and atopic dermatitis, mostly with narrowband 311 nm lamps.

Uveitis

Uveitis (iritis, choroiditis) is inflammation of the uvea, the eye's middle layer (iris, ciliary body, choroid). Causes include autoimmune disease, infection, injury, and lymphoma; treated with corticosteroids and steroid-sparing immunosuppressants.

Uvula

Uvula (palatine uvula), the teardrop of tissue hanging from the soft palate; secretes saliva, seals the nasopharynx during swallowing, aids gag reflex and uvular speech sounds; found only in humans.

Uvulopalatopharyngoplasty

Uvulopalatopharyngoplasty (UPPP) is an operation removing excess tissue from the uvula, soft palate, and pharynx, plus the tonsils, to treat snoring and obstructive sleep apnea.

UZ-CHS-BC study

The UZ-CHS-BC study, or University of Zimbabwe College of Health Sciences Birth Cohort study, follows 1,200 mother-infant pairs in Harare to compare HIV-exposed and unexposed infants.

Oct 20, 2026

Vaborbactam

Vaborbactam (RPX7009) is a cyclic boronic acid, non-beta-lactam beta-lactamase inhibitor inhibiting class A and C serine beta-lactamases including KPC, not class B or D. Co-formulated with meropenem as Vabomere/Vaborem, FDA-approved 2017 for complicated urinary tract infection.