edgepedia

Molecular biology of the cell / cell signaling

200 articles

Jin Jiang

Jin Jiang (蒋进) is a molecular biologist and professor at UT Southwestern Medical Center in Dallas, known for defining how PKA and GSK3 regulate the Hedgehog pathway.

Joachim Herz

Joachim Herz is a German-born physician-scientist and molecular biologist at UT Southwestern Medical Center in Dallas, known for discovering LRP and showing that LDL receptor family members transmit Reelin signals in the brain.

Johannes L. Bos

Johannes L. Bos, known as Hans Bos, is a Dutch molecular cancer researcher, professor at UMC Utrecht from 1991, known for showing Ras mutations are frequent in human tumors and for discovering Epac.

John D. York

John D. York, also published as J.D. York, is a biochemist who studies inositol phosphate signaling and became chair of biochemistry at Vanderbilt University Medical Center.

Jonathan A. Cooper

Jonathan A. Cooper is an English-born cell biologist and emeritus professor at Fred Hutch Cancer Center in Seattle, best known for establishing that Ras binds directly to Raf kinase.

Jyoti R. Misra

Jyoti R. Misra is an American biologist known for defining the CncC/Nrf2–Keap1 detoxification pathway in fruit flies and for work on Fat signaling in the Hippo pathway.

Kai G. Zinn

Kai G. Zinn, also published as Kai Zinn, is a molecular biologist at Caltech whose lab maps interactions among human and Drosophila cell surface proteins.

Ken Inoki

Ken Inoki is a Japanese-born molecular biologist and physician-scientist at the University of Michigan whose 2002 to 2006 papers showed how TSC2 integrates growth-factor, energy, and Wnt signals to regulate mTORC1.

Klaus M. Hahn

Klaus M. Hahn is an American cell biologist and Thurman Distinguished Professor of Pharmacology at UNC-Chapel Hill, known for fluorescent biosensors and optogenetic tools like photoactivatable Rac1.

Kunihiro Matsumoto

Kunihiro Matsumoto (松本 邦弘) is a Japanese molecular geneticist, professor at Nagoya University from 1990 to 2017, known for yeast signal transduction and C. elegans nerve-cell regeneration research.

Larry A. Feig

Larry A. Feig is a molecular biologist and professor at Tufts University School of Medicine in Boston, known for discovering calcium-activated Ras-GRF exchange factors and studying inherited stress effects.

Laura A. Johnston

Laura A. Johnston is an American molecular biologist at Columbia University known for showing that Myc controls organ size through cell competition in fruit flies.

Len Stephens

Len Stephens, also known as Len R. Stephens, is a molecular biologist at the Babraham Institute near Cambridge known for defining how PI3K signaling works in neutrophils.

Lena Claesson-Welsh

Lena Claesson-Welsh is a Swedish vascular biologist and Professor of Medical Biochemistry at Uppsala University, known for mapping VEGF receptor signaling and vascular permeability, elected to EMBO in 2017.

Lewis T. Williams

Lewis T. ("Rusty") Williams is an American physician-scientist, a Howard Hughes Medical Institute Investigator from 1983 to 1993, and a member of the National Academy of Sciences.

Louis J. Ignarro

Louis J. Ignarro, born 1941 in Brooklyn, is an American pharmacologist at UCLA who shared the 1998 Nobel Prize for identifying nitric oxide as the blood-vessel-relaxing signaling molecule.

M. Luisa Iruela‐Arispe

M. Luisa Iruela-Arispe is a Spanish-born cell and developmental biologist known for work on angiogenesis and VEGF signaling, and chair of Cell and Developmental Biology at Northwestern.

Marc Therrien

Marc Therrien is a Canadian molecular biologist at the Université de Montréal who identified the RAS signaling protein KSR in 1995 and became Executive Director of IRIC in 2024.

Marco E. Bianchi

Marco E. Bianchi, also known as Marco Bianchi, is an Italian molecular biologist who established the chromatin protein HMGB1 as an extracellular danger signal that triggers inflammation.

Marek Mlodzik

Marek Mlodzik is a molecular geneticist studying planar cell polarity and Wnt/Frizzled signaling in Drosophila; he chairs Cell, Developmental, and Regenerative Biology at the Icahn School of Medicine at Mount Sinai.

Mariann Bienz

Mariann Bienz is a molecular biologist known for her work on Wnt signal transduction, the Wnt enhanceosome, and Dishevelled polymerisation; she worked at the MRC Laboratory of Molecular Biology in Cambridge.

Marilyn D. Resh

Marilyn D. Resh is an American cell biologist and biochemist, emeritus at Memorial Sloan Kettering, known for how fatty acids attached to proteins regulate their structure and function.

Mark R. Philips

Mark R. Philips is a professor at NYU Grossman School of Medicine known for showing that Ras, the most frequently mutated oncogene in cancer, signals on internal membranes.

Mark W. Bitensky

Mark W. Bitensky was an American molecular biologist and Yale-trained physician known for work on cyclic AMP signaling, adenylate cyclase regulation, and light-activated retinal enzymes.

Martin D. Bootman

Martin D. Bootman is a British cell biologist at The Open University, known for 1990s work at the Babraham Institute showing that cellular calcium waves are built from elementary local release events.

Mary Dasso

Mary Dasso is an American cell biologist who heads the Section on Cell Cycle Regulation at NIH's NICHD in Bethesda, Maryland, studying the Ran GTPase and SUMOylation in mitosis.

Masayuki Yamamoto

Masayuki Yamamoto (山本雅之, born 1954) is a Japanese molecular biologist who discovered the Keap1-Nrf2 system, the cell's principal defense against oxidative stress, and won the Japan Academy Prize in 2014.

Massimo Santoro

Massimo Santoro is an Italian cell and molecular biologist at the University of Padova who studies redox metabolism and angiogenesis, known for work on the enzyme UBIAD1.

Matthew Freeman (cell biologist)

Matthew Freeman is a British cell biologist and geneticist, Professor of Pathology at Oxford, known for discovering rhomboid proteases and iRhoms, and elected a Fellow of the Royal Society in 2006.

Maxime Schwartz

Maxime Schwartz, born in 1940, is a French molecular biologist who researched positive transcriptional regulation in bacteria and directed the Institut Pasteur from 1988 to 1999.