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Translation and ribosome structure

42 articles

Albert E. Dahĺberg

Albert E. Dahĺberg, also known as A.E. Dahlberg, was an American molecular biologist and Brown University professor known for his 1989 Cell review on ribosomal RNA in protein synthesis.

Albert Weixlbaumer

Albert Weixlbaumer is a structural biologist who led the 2008 RF2 ribosome structure behind the 2009 Chemistry Nobel and runs a lab at the IGBMC in France.

Alexander S. Mankin

Alexander S. Mankin is a molecular biologist and Distinguished Professor at the University of Illinois Chicago who studies the ribosome and how antibiotics inhibit protein synthesis.

Barbara S. Schuwirth

Barbara S. Schuwirth is a German structural biologist who, as first author, published the first near-atomic-resolution crystal structure of the intact bacterial 70S ribosome in 2005.

Brian T. Wimberly

Brian T. Wimberly is an American structural biologist, first author of the 2000 Nature paper reporting the crystal structure of the bacterial 30S ribosomal subunit.

Bruce A. Maguire

Bruce A. Maguire is a ribosome biochemist whose 2005 Molecular Cell paper on protein L27 was cited in the Nobel Committee's 2009 Chemistry advanced information.

C.M.T. Spahn

Christian M. T. Spahn is a German biochemist and structural biologist at Charité in Berlin who uses cryo-electron microscopy to determine the structures of eukaryotic ribosomes.

Daniel N. Wilson

Daniel N. Wilson is a New Zealand–trained molecular and structural biologist, professor of biochemistry at Universität Hamburg since 2016, who studies ribosomes, translation stalling, and antibiotics.

Dino Moras

Dino Moras, born 1944, is a French structural biologist and CNRS research director at the IGBMC in Strasbourg, known for crystallographic studies of transfer RNA and nuclear hormone receptors.

Ditlev E. Brodersen

Ditlev E. Brodersen is a Danish structural molecular biologist, professor of structural microbiology at Aarhus University since 2021, known for work on antibiotic binding to the bacterial ribosome.

Frank Schluenzen

Frank Schluenzen is a structural biologist who co-determined high-resolution structures of bacterial ribosomal subunits, showing antibiotics bind only RNA, and later worked in scientific computing at DESY.

Gregor Blaha

Gregor Blaha is a biochemist and associate professor at the University of California, Riverside since 2022, known for bacterial ribosome work and cryo-EM structures of ribosome-RNA polymerase complexes that helped reignite the study of transcription-translation coupling.

Haiwei Song

Haiwei Song is a structural biologist and Research Director at A*STAR's Institute of Molecular and Cell Biology in Singapore, known for the crystal structure of human eRF1.

Harry F. Noller

Harry F. Noller is an American molecular biochemist at UC Santa Cruz who established that ribosomal RNA is the functional heart of the ribosome, winning the 2017 Breakthrough Prize.

Heinz-Günter Wittmann

Heinz-Günter Wittmann (1927–1990) was a German biochemist who directed the Max Planck Institute for Molecular Genetics in Berlin and sequenced nearly all E. coli ribosomal proteins.

Ira G. Wool

Ira G. Wool (1925–2012) was an American biochemist and physician at the University of Chicago whose insulin research opened the study of the eukaryotic ribosome.

J.H.D. Cate

J.H.D. Cate, also known as Jamie H. D. Cate, is an American structural biologist at UC Berkeley known for crystal structures of the bacterial ribosome.

James M. Ogle

James M. Ogle is a structural biologist who, in Venki Ramakrishnan's group at the MRC Laboratory of Molecular Biology, solved the 30S ribosomal subunit structures explaining decoding.

Joan Folkes

Joan P. Folkes, born 1927, is a biochemist who worked on bacterial protein synthesis and antibiotic action at Cambridge, nominated once for the 1956 Nobel Prize in Chemistry.

Joshua S. Weinger

Joshua S. Weinger is a biochemist who, in Scott Strobel's Yale laboratory, led the 2004 study showing the tRNA 2'-hydroxyl group is essential to ribosomal catalysis.

Karin Musier‐Forsyth

Karin Musier-Forsyth is an American biochemist who studies aminoacyl-tRNA synthetases and HIV-1 RNA packaging, and directs the Center for RNA Biology at Ohio State University.

Kazimierz B. Gromadski

Kazimierz B. Gromadski, also known as Kirill B. Gromadski, is a biochemist at the University of Witten/Herdecke who measured how the ribosome selects correct tRNAs.

Knud H. Nierhaus

Knud H. Nierhaus (1941–2016) was a German biochemist at the Max Planck Institute for Molecular Genetics in Berlin, known for reconstituting the 50S ribosomal subunit and discovering the E site.

Loren Dean Williams

Loren Dean Williams is a biochemist and professor at the Georgia Institute of Technology known for the iron(II) RNA cofactor hypothesis and an accretion model of ribosome evolution.

Måns Ehrenberg

Måns Ehrenberg is a Swedish molecular biologist and professor emeritus at Uppsala University, known for quantitative work on the bacterial ribosome and a member of the Royal Swedish Academy of Sciences.

Marat Yusupov

Marat Yusupov, born 1956, is a Russian-born French structural biologist at the IGBMC near Strasbourg who determined the first crystal structures of bacterial and eukaryotic ribosomes.

Maria Selmer

Maria Selmer is a structural biologist and Professor of Structural Biology at Uppsala University, studying bacterial ribosome function and antibiotic resistance mechanisms with cryo-EM and X-ray crystallography.

Mario Halić

Mario Halić, born 1976, is a Croatian-born molecular and structural biologist who leads a lab at St. Jude Children's Research Hospital in Memphis, known for discovering Dicer-independent primal small RNAs in fission yeast.

Martin Pioletti

Martin Pioletti is a structural biologist, first author of the 2001 EMBO Journal paper reporting a 3.2 Å crystal structure of the 30S ribosomal subunit from Thermus thermophilus.

Paul Schimmel

Paul Reinhard Schimmel is an American biochemist at Scripps Research and MIT known for his work on aminoacyl tRNA synthetases, the genetic code, and cofounding several biotechnology companies.