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Metabolism and mitochondrial physiology

54 articles

Leonard Guarente

Leonard Guarente is an American molecular biologist and aging researcher, the Novartis Professor of Biology at MIT known for showing that sirtuins regulate aging through NAD, and a founder of Elysium Health.

Lionel H. Opie

Lionel H. Opie (L. H. Opie) was a South African cardiologist at the University of Cape Town who showed how beta-blockers protect the heart during a heart attack.

Luca Scorrano

Luca Scorrano, born 1971 in Padua, is an Italian physician-scientist and Full Professor of Biochemistry at the University of Padua, known for work on OPA1 and mitochondrial cristae.

Matthew D. Hirschey

Matthew D. Hirschey is an American metabolism researcher and Associate Professor at the Duke Molecular Physiology Institute, known for his 2010 Nature paper on the sirtuin SIRT3.

Max Rubner

Max Rubner (1854–1932) was a German physiologist and hygienist, founder of scientific nutrition physiology, who determined the metabolizable energy of nutrients and formulated the law of surface area.

Nils-Göran Larsson

Nils-Göran Larsson is a Swedish physician-scientist in mitochondrial genetics, Professor at Karolinska Institutet since 2016 and a former founding Director of the Max Planck Institute for Biology of Ageing.

Peter J. Roach

Peter J. Roach (1948–2022) was an English-born biochemist at the Indiana University School of Medicine who established the role of glycogen phosphorylation in Lafora disease.

Peter Rehling

Peter Rehling (born 1966) is a German biochemist who has led the Institute of Cellular Biochemistry at the University Medical Center Göttingen since 2007, known for work on mitochondrial protein import and respiratory-chain assembly.

Ralph DeBerardinis

Ralph J. DeBerardinis is an American physician-scientist at UT Southwestern in Dallas who studies nutrient use in tumors and inherited metabolic diseases, showing in 2017 that human lung tumors consume lactate as fuel.

Robert E. Gerszten

Robert E. Gerszten is an American physician-scientist in cardiovascular medicine and metabolomics, chief of cardiovascular medicine at Beth Israel Deaconess Medical Center and a Harvard Medical School professor.

Robert R. Wolfe

Robert R. Wolfe (R. R. Wolfe) is an American muscle-metabolism researcher known for stable isotope tracer methodology and burn catabolism research, now a geriatrics professor and center director at UAMS in Little Rock.

Rolf Luft

Rolf Luft (1914–2007) was a Swedish endocrinologist at the Karolinska Institutet in Stockholm, known for founding mitochondrial medicine and for decades of work on the pathogenesis and treatment of diabetes mellitus.

Ronald M. Evans

Ronald M. Evans is an American molecular biologist at the Salk Institute known for discovering the nuclear hormone receptor superfamily, gene-regulating proteins targeted by many drugs.

S.P. Allison

S.P. Allison, or Simon P. Allison, is a British physician-scientist in clinical nutrition and metabolism at Nottingham, known for his 1979 work using insulin to spare protein after injury.

Stacy Sims

Stacy T. Sims, exercise physiologist and nutrition scientist (PhD, University of Otago, 2006), senior research associate at AUT's SPRINZ and adjunct at Stanford Lifestyle Medicine; author of ROAR and Next Level and lead author of the 2023 ISSN female athlete nutrition position stand; known for "women are not small men" and later retracting menstrual phase-based training advice.

Teresa A. Davis

Teresa A. Davis, also known as Teresa Ann Davis, is an American nutrition scientist known for her research on muscle protein synthesis in newborns, elected to the National Academy of Medicine in 2024.

Thomas Langer

Thomas Langer is a German biochemist who studies mitochondrial proteases and quality control; he directs the Department of Mitochondrial Proteostasis at the Max Planck Institute for Biology of Ageing in Cologne.

Timothy J. Kieffer

Timothy J. Kieffer is a Canadian metabolism researcher and Professor Emeritus at the University of British Columbia, known for engineering insulin-producing cells and advancing stem-cell diabetes therapy into clinical trials.

Timothy M. Cox

Timothy M. Cox, born 1948, is a British metabolic medicine specialist and Professor of Medicine Emeritus at Cambridge, known for lysosomal disease research and gene therapy.

Ting-Kai Li

Ting-Kai Li (1934–2018) was a Chinese-born American physician-scientist in alcohol and addiction research who directed NIAAA from 2002 to 2008, created the alcohol-preferring rat, and was elected to the Institute of Medicine in 1999.

Toren Finkel

Toren Finkel is an American physician-scientist who directs the Aging Institute at the University of Pittsburgh, known for research on reactive oxygen species, sirtuins, and the biology of aging.

William Christopher Stadie

William Christopher Stadie (1886–1959) was an American physician and metabolic physiologist at the University of Pennsylvania who pioneered oxygen therapy for pneumonia and studied insulin action.

Zoltàn Arany

Zoltàn Arany, also known as Zolt Arany, is an American cardiologist at the University of Pennsylvania, known for research on peripartum cardiomyopathy, a heart failure of late pregnancy.

Zoltan Pierre Arany

Zoltan Pierre Arany is a cardiologist and physician-scientist at the University of Pennsylvania who studies how metabolism drives disease in the heart, skeletal muscle, and blood vessels, and became Chair of Physiology in 2025.