72,234 articles
HSPA8
HSPA8, also called HSC70 or HSP73, is the human chromosome 11 gene encoding the constitutive Hsp70-family chaperone that folds nascent proteins, uncoats clathrin vesicles, and drives chaperone-mediated autophagy, unlike stress-inducible HSPA1A.
HSPA9
HSPA9 (mortalin, mtHSP70, GRP75, PBP74) is a human chromosome 5q31.2 gene encoding the mitochondrial HSP70 chaperone that drives protein import, folding, iron-sulfur cluster biogenesis, and mitophagy; mutations cause EVEN-PLUS syndrome and sideroblastic anemia.
HSPB1
HSPB1 (HSP27, heat shock protein beta-1) is a human small heat shock protein gene encoding an ATP-independent chaperone; mutations cause Charcot-Marie-Tooth disease type 2F and distal hereditary motor neuropathy 2B.
HSPB1-associated protein 1
HSPB1-associated protein 1 (HSPBAP1, PASS1, UniProt Q96EW2) is a 488-aa human JmjC-domain protein binding HSPB1/HSP27, suppressing its heat-shock protection; upregulated in intractable epilepsy temporal neocortex.
HSPB8
HSPB8 (Hsp22, H11, E2IG1) is a 22 kDa human small heat shock protein on chromosome 12q24.23 that binds BAG3 to drive chaperone-assisted selective autophagy; mutations cause dHMN2A, CMT2L, and myofibrillar myopathy.
HSPD1
HSPD1 (HSP60, CPN60, SPG13) is a human gene at 2q33.1 encoding the mitochondrial chaperonin Hsp60, which folds about half of mitochondrial matrix proteins; mutations cause SPG13 hereditary spastic paraplegia and hypomyelinating leukodystrophy.
HSPG2
HSPG2, heparan sulfate proteoglycan 2, is a protein-coding gene on chromosome 1p36.12 that encodes perlecan, a large basement membrane proteoglycan; biallelic mutations cause Schwartz-Jampel syndrome type 1 and lethal dyssegmental dysplasia.
HT-1080
HT-1080 (HT1080, CVCL_0317, ATCC CCL-121) is a human fibrosarcoma cancer cell line established in 1972 from a 35-year-old man; NRAS-mutant, IDH1 R132C, used in sarcoma research, 3D migration studies, and Shire therapeutic protein manufacturing.
HT-1376
HT-1376 (HT1376, CVCL_1292) is a human bladder transitional cell carcinoma cell line established in 1977 from a 58-year-old woman, near-tetraploid, with RB1, TP53, TERT promoter, and PTEN alterations, used in muscle-invasive bladder cancer research.
HT-29
HT-29 (ATCC HTB-38, CVCL_0320) is a human colorectal adenocarcinoma cell line established in 1964 by J. Fogh from a 44-year-old woman's colon tumor; adherent, enterocyte-like, drug-sensitive, and widely used in cancer, GI barrier, and CRISPR screening research.
HT-3
HT-3 is a human cervical carcinoma cell line established in 1963 by Jorgen Fogh at Sloan Kettering from a metastatic lymph node, long used as an HPV-negative comparator.
HTH-type transcriptional regulator DicA, C-terminal region
HTH-type transcriptional regulator DicA, C-terminal region: the C-terminal region of DicA, a predicted helix-turn-helix (HTH) DNA-binding transcriptional regulator; class-level features of HTH regulators and related phage repressor domain organization.
HTR1B
HTR1B (5-HT1B receptor, formerly 5-HT1D beta, UniProt P28222) is an intronless human gene on 6q14.1 encoding a Gi/o-coupled serotonin GPCR that inhibits adenylate cyclase, regulates monoamine release, and is targeted by triptan antimigraine drugs.
HTR2A
HTR2A (5-HT2A receptor gene, HGNC 5293) is a human chromosome 13q14.2 gene encoding a Gq-coupled serotonin GPCR, the target of psychedelics and a pharmacogenomic marker for antidepressant response.
HTR2C
HTR2C, also called 5-HT2C or formerly 5-HT1C, is the X-linked human gene for a serotonin 2C G protein-coupled receptor, the only GPCR known to undergo RNA editing, targeted by the obesity drug lorcaserin.
HTRA1
HTRA1 (HtrA serine peptidase 1, PRSS11) is a chromosome 10q26 gene encoding a secreted trimeric serine protease that inhibits TGF-beta signaling; loss causes CARASIL and variants link to AMD.
Hua Gu
Hua Gu is a Chinese-born immunologist who directs the Molecular Immunology Research Unit at the Montreal Clinical Research Institute and studies T and B cell signaling.
Hua Hua (giant panda)
Hua Hua (He Hua, 和花, Cheng Hehua), female giant panda born 2020 at Chengdu Research Base of Giant Panda Breeding, twin of He Ye; China's top internet-celebrity panda, viral for her round onigiri shape, Honorary Director of Chengdu Culture and Tourism, distinct from the 1997-born Hua Hua loaned to Atlanta as Lun Lun.
Hua Yu (cancer researcher)
Hua Yu is a cancer researcher and Wilder Professor at City of Hope in Duarte, California, whose laboratory established the signaling protein STAT3 as a molecular target for cancer immunotherapy.
Huabancai
Huabancai (滑板菜) is a wild mountain vegetable from the climbing perennial vine Parabaena sagittata, typically stir-fried or cooked with meat in Xishuangbanna, Yunnan, where dwindling wild supplies prompted a patented cutting-propagation method.
Huagai San
华盖散 (Huagai San, Canopy Powder) is a classical Chinese herbal formula from the Song dynasty Taiping Huimin Heji Jufang for wind-cold cough with phlegm; studied in cough variant asthma and chronic bronchitis and registered as granules in Macau and Taiwan.
Huaganjian
化肝煎 (Huaganjian), a seven-herb classic Chinese formula from Zhang Jingyue's Ming-era Jingyue Quanshu, vol. 51; treats liver depression transforming into fire with flank pain and bleeding; one of China's first 100 trial-exempt classic formulas.
Huai Sai Wildlife Breeding Centre
Huai Sai Wildlife Breeding Centre (ศูนย์เพาะเลี้ยงสัตว์ป่าห้วยทราย), also called Huai Sai Zoo, is a Thai government wildlife breeding and rescue facility in Cha-am District, Phetchaburi Province.
Huan‐Xiang Zhou
Huan-Xiang Zhou is a biophysicist, professor and LAS Endowed Chair at the University of Illinois Chicago since 2017, known for work on protein binding kinetics, ion-channel gating, and biomolecular condensates.
Huanan Seafood Wholesale Market (华南海鲜批发市场)
Huanan Seafood Wholesale Market (华南海鲜批发市场), a 1,500-vendor market in Hankou, Wuhan, closed 1 January 2020 after early COVID-19 cases clustered there; environmental SARS-CoV-2 contamination was confirmed but its source remains undetermined.
Huangge Rong
黄葛榕 (Ficus virens, also 黄葛树/黄桷树/大叶榕) is a large deciduous fig of Moraceae native to south and southwest China; Chongqing's city tree and namesake of Huangguoshu Waterfall.
Huangjiu (黄酒)
Huangjiu (黄酒), Chinese yellow rice wine, is a fermented cereal-grain beverage made with yeast and Qu starter, 8–20% alcohol, over 5,000 years old, with Shaoxing as its most renowned style.
Huanglian Gao
黄连膏 (Huanglian ointment, Coptis ointment): a traditional Chinese external oil ointment. The classical Qing Yizong Jinjian version, in the Ancient Classic Formulas catalogue, uses Coptis, Phellodendron, Rehmannia, Angelica tail, and turmeric in sesame oil and wax for sores; distinct from other same-named formulas.
Huangqi Guizhi Wuwu Decoction
黄芪桂枝五物汤 (Huangqi Guizhi Wuwu Decoction, HGWD), a five-herb classic formula from the Jingui Yaolue of Zhang Zhongjing, treats blood bi and is used for diabetic and chemotherapy-induced peripheral neuropathy.
Huangqi Tang
黄芪汤 (Huangqi decoction), a classical Chinese medicine formula from the Taiping Huimin Heji Jufang; variants contain astragalus with tangerine peel, hemp seed, and honey, or astragalus and licorice 6:1 (黄芪六一汤); studied in hepatitis B cirrhosis.