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Hyaluronic acid injection
A hyaluronic acid injection delivers hyaluronan gel into tissue, either into the knee joint to relieve osteoarthritis pain or into facial soft tissue to fill lines and restore volume.
Hyaluronidase (drug)
Hyaluronidase (rHuPH20, HYLENEX recombinant) is an injectable enzyme degrading hyaluronic acid, FDA-approved for hypodermoclysis, drug dispersion, and urography, and used off-label to dissolve HA fillers and as an anesthesia adjunct.
Hyaluronidase (gene)
Hyaluronidase (gene) family: six human genes HYAL1, HYAL2, HYAL3, HYAL4, SPAM1/PH-20, HYALP1 on chromosomes 3p21.3 and 7q31.3, encoding hyaluronan-degrading enzymes; HYALP1 is a human pseudogene, rodents add HYAL5.
Hyaluronidase deficiency
Hyaluronidase deficiency (MPS IX, Natowicz syndrome) is an ultra-rare autosomal recessive lysosomal storage disease caused by HYAL1 deficiency, with hyaluronan storage, periarticular masses, and joint disease; only four patients reported.
Hyangyak Jipseongbang
Hyangyak Jipseongbang (향약집성방) is an 85-volume Korean medical encyclopedia completed in 1433 under King Sejong, gathering prescriptions based on medicinal herbs produced in the Korean peninsula.
Hybodus
Hybodus is an extinct genus of hybodontiform shark, type species H. reticulatus from the Lower Jurassic of Lyme Regis; a wastebasket taxon of 2-3 m spined sharks from Triassic to Late Cretaceous.
Hybosoridae
Hybosoridae, scavenger scarab beetles, are a cosmopolitan Scarabaeoidea family of 96 genera and 723 species in five extant subfamilies, defined by a three-segmented antennal club and tarsi inserted before the protibial apex.
Hybotidae
Hybotidae: a worldwide family of predaceous dance flies (Diptera, Empidoidea), defined by a palpifer, fore tibial gland, bare laterotergite, and unbranched R4+5; subfamilies Hybotinae, Ocydromiinae, Tachydromiinae.
Hybrid (biology)
Hybrid (biology): offspring of genetically distinct parents, often different species. Plant hybrids show sterility or inviability, drive speciation via polyploidy or introgression, and power heterosis in hybrid crops.
Hybrid ablation
Hybrid ablation is a treatment for atrial fibrillation that combines minimally invasive surgical ablation on the outside of the heart with catheter ablation on the inside, so lesions extend through the full atrial wall.
Hybrid argon plasma coagulation
Hybrid argon plasma coagulation (HAPC, also HybridAPC) is an endoscopic technique that combines submucosal saline injection with argon plasma coagulation through one catheter, mainly for Barrett's esophagus ablation.
Hybrid capture
Hybrid capture is a targeted sequencing method that enriches specific genomic regions before sequencing, using biotinylated probes and streptavidin beads; it underlies exome sequencing and custom clinical panels.
Hybrid coronary revascularization
Hybrid coronary revascularization (HCR) combines minimally invasive LIMA-LAD bypass grafting with PCI for non-LAD lesions in multivessel coronary disease; introduced in the mid-1990s, it lowers perioperative morbidity versus CABG but raises repeat revascularization.
Hybrid imaging
Hybrid imaging is a medical imaging approach combining an anatomical scan (CT or MRI) with a functional scan (PET or SPECT), with main pairs PET/CT, PET/MRI, and SPECT/CT.
Hybrid larch
Hybrid larch, also called Dunkeld larch, is the hybrid of European larch and Japanese larch, first recognized at Dunkeld, Scotland, in 1905 and grown for timber because it outgrows both parents.
Hybrid maize
Hybrid maize is corn produced by crossing two genetically distinct inbred parent lines; first published in 1908, it spread across nearly all US corn acreage by 1960.
Hybrid Renal Replacement Therapy
Hybrid renal replacement therapy (SLED, PIRRT, extended daily dialysis) combines CRRT-like slow solute and fluid removal with intermittent hemodialysis equipment; trials show mortality and hemodynamic outcomes comparable to CRRT at lower cost.
Hybrid repair
Hybrid repair is a vascular surgical technique that combines open debranching of aortic branch vessels with endovascular stent-graft exclusion of the aneurysm, avoiding parts of full open repair.
Hybrid rice
Hybrid rice: F1 rice from crosses of distinct parents exploiting heterosis, developed in China from Yuan Longping's 1960 work; three-line CMS, two-line EGMS, and third-generation GMS systems cover about half of China's rice area.
Hybrid striped bass
Hybrid striped bass (Palmetto bass, Sunshine bass, wiper), a Morone saxatilis × M. chrysops cross first made in 1965, is the fourth most farmed US finfish, about 12 million lb yearly, $50 million farm gate value.
Hybrid tea rose
The hybrid tea rose is a class of modern garden rose bred from tea roses and hybrid perpetuals, the classic long-stemmed rose of florists and cutting gardens.
Hybridisation
Hybridisation (hybridization): joining of separate entities. In genomics, complementary DNA/RNA strands base-pair into double-stranded hybrids, underpinning PCR, FISH, and blots; in evolution, interbreeding between distinct populations; also hybrid drugs, medicines, and trial designs.
Hybridization chain reaction
Hybridization chain reaction (HCR) is an enzyme-free, isothermal nucleic acid amplification method introduced by Dirks and Pierce in 2004, used mainly for multiplexed fluorescence in situ hybridization and biosensing.
Hybridoma technology
Hybridoma technology is a laboratory method for producing monoclonal antibodies by fusing short-lived antibody-producing B cells with immortal myeloma cells; described in 1975, it earned the 1984 Nobel Prize.
Hybutimibe
Hybutimibe (海博麦布, hyzetimibe, HS-25; brand Saisimei) is an oral NPC1L1 cholesterol absorption inhibitor made by Zhejiang Hisun, approved in China June 2021 for primary hypercholesterolemia, dosed 10 or 20 mg daily, adding about 16% LDL-C reduction to statins.
HYCOR study
HYCOR (Hybrid-sensor Breath Analysis for Colorectal Cancer Screening, NCT05173077) is a University of Latvia ERDF-funded project, 2021-2023, testing a MOX-plus-IR hybrid breath sensor analyzer and GC-MS VOC markers for colorectal cancer screening, distinct from the unrelated Hycor Biomedical allergy company.
Hydnaceae
Hydnaceae (Chevall., 1826), also treated as Cantharellaceae, is a family of Cantharellales basidiomycete fungi containing chanterelles, Craterellus, and Hydnum; seventeen genera confirmed, mostly ectomycorrhizal, edible, worldwide.
Hydnellum peckii
Hydnellum peckii, the bleeding tooth fungus or strawberries and cream, is an inedible Bankeraceae tooth fungus whose young caps exude red droplets and whose peppery flesh contains the anticoagulant atromentin; it grows mycorrhizally with conifers in North America and Europe.
Hydnocarpus kurzii
Hydnocarpus kurzii, commonly called chaulmoogra, is a dioecious evergreen tree native from Assam to Peninsular Malaysia whose seed oil was a standard historical treatment for leprosy.
Hydra (genus)
Hydra (genus) is a genus of small freshwater cnidarian polyps in Hydrozoa, family Hydridae, famed for regenerating whole animals from fragments; four species groups, ~200 mya origin, green H. viridissima hosts Chlorella.