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Midostaurin

Midostaurin (Rydapt) is an oral multikinase inhibitor derived from staurosporine, approved in 2017 as the first targeted treatment for FLT3-mutated acute myeloid leukemia and for advanced systemic mastocytosis.

Midwife

Midwife: educated, registered professional providing autonomous care during pregnancy, birth, and postpartum, per ICM definition; also called midwifery-led care; evidence shows fewer caesareans and instrumental births, 900,000 global shortage.

Midwifery

Midwifery is a health profession and model of care in which licensed midwives support women and newborns through pregnancy, labor, birth, and the postpartum period, in homes, clinics, or hospitals.

Mien-Chie Hung

Mien-Chie Hung (洪明奇) is a Taiwanese cancer biologist known for work on the HER-2/neu oncogene and EGFR signaling, who served as president of China Medical University from 2019 to 2025.

Mietens syndrome

Mietens syndrome, or Mietens-Weber syndrome, is an extremely rare autosomal recessive disorder (OMIM 249600, ORPHA:2557) first described in 1966, marked by sclerocornea, nystagmus, strabismus, elbow flexion contractures with radial head dislocation, short stature, and intellectual disability; nine cases reported.

Mifamurtide acid

Mifamurtide (L-MTP-PE, Mepact) is a synthetic NOD2-activating liposomal immunostimulant approved in the EU in 2009 for high-grade resectable non-metastatic osteosarcoma in patients aged 2 to 30.

Mifepristone

Mifepristone, also known as RU-486 and sold as Mifeprex, is a drug that blocks progesterone; combined with misoprostol, it ends pregnancies up to ten weeks in the United States.

Migalastat

Migalastat (Galafold, 1-deoxygalactonojirimycin) is Amicus Therapeutics' oral pharmacological chaperone for Fabry disease, approved by EMA 2016 and FDA 2018, for patients with amenable GLA mutations defined by the GLP-HEK assay (≥1.2-fold and ≥3% wild-type alpha-Gal A increase), dosed 123 mg every other day.

Miglitol

Miglitol (Glyset, Diastabol) is an oral alpha-glucosidase inhibitor, a desoxynojirimycin derivative approved by the FDA in 1996, used as adjunct to diet and exercise in type 2 diabetes; dosed 25-100 mg three times daily, renally excreted unchanged.

Miglustat

Miglustat (N-butyldeoxynojirimycin, Zavesca) is an oral glucosylceramide synthase inhibitor, a substrate reduction therapy for type 1 Gaucher disease and Niemann-Pick type C neurological manifestations, and part of Pompe combination therapy.

Mignon L. Loh

Mignon L. Loh is an American pediatric hematologist-oncologist and leukemia researcher who directs the Ben Towne Center for Childhood Cancer Research at Seattle Children's Hospital.

Migraine

Migraine: a primary headache disorder of recurrent one-sided throbbing attacks with nausea and light sensitivity, classified in ICHD-3; global prevalence about 14%, treated with triptans, gepants, and CGRP preventives.

Migraine with aura

Migraine with aura (classic migraine, ICHD-3 code 1.2): recurrent attacks of gradually spreading, fully reversible visual, sensory, or other neurological symptoms lasting 5-60 minutes, usually followed by headache; mechanism linked to cortical spreading depression; carries elevated stroke risk.

Migraine without aura

Migraine without aura (common migraine, ICHD-3 1.1, ICD-11 8A80.0) is the most common migraine form, about 70-75% of cases: recurrent 4-72 hour unilateral pulsating headache with nausea or photophobia/phonophobia, no aura.

Migraine-induced stroke

Migraine-induced stroke, or migrainous infarction (ICD-11 8B22.9), is a rare ischemic stroke during a migraine with aura attack when aura lasts over 60 minutes; mostly posterior circulation, young women, favorable prognosis.

Migration and invasion-inhibitory protein

MIIP (IIP45), a 43 kDa tumor-suppressor protein encoded at human chromosome 1p36.22, inhibits cell migration and invasion by binding HDAC6, IGFBP2, Cdc20, and ITGB3; its loss or deletion promotes metastasis in several cancers.

Migratory beekeeping

Migratory beekeeping is the long-distance movement of honey bee colonies by truck to rented pollination contracts, moving roughly 1.8 million colonies to California's almond bloom each February.

Migratory Bird Treaty Act of 1918

The Migratory Bird Treaty Act of 1918 (MBTA) is a United States federal law making it unlawful to hunt, kill, or possess protected migratory birds without a permit.

Migratory species

Migratory species: wild animals whose populations cyclically and predictably cross national borders, also called migratory animals under the CMS/Bonn Convention. Key facts: CMS in force 1983, 133 Parties, 44-49% of listed species declining, Appendix I/II listing system.

Miguel A. Hernán

Miguel A. Hernán is a physician-epidemiologist and biostatistician, Kolokotrones Professor at the Harvard T.H. Chan School of Public Health, known for target trial emulation and the textbook Causal Inference: What If.

Miguel Ángel J. Márquez Ruiz

Miguel Ángel Jacinto Márquez Ruiz (1942–2026), Mexican avian pathologist and virologist, UNAM professor, RACVE foreign corresponding academic, and historian of veterinary medicine in New Spain.

Miguel Ángel Martínez‐González

Miguel Ángel Martínez-González, born 1957, is a Spanish physician and epidemiologist at the University of Navarra and Harvard, known for the PREDIMED Mediterranean diet trial.

Miguel B. Araújo

Miguel B. Araújo, also known as Miguel Bastos Araújo, is a Portuguese biogeographer at the Spanish National Research Council in Madrid who studies climate change effects on biodiversity.

Miguel Beato

Miguel Beato is a Spanish molecular biologist known for work on steroid hormone gene regulation through chromatin; he founded and directed the Centre for Genomic Regulation in Barcelona until 2011.

Miguel C. Seabra

Miguel C. Seabra (Miguel Pedro Pires Cardoso de Seabra), born 1962, is a Portuguese cell biologist at NOVA Medical School known for choroideremia gene therapy.

Miguel López (Spanish physiologist)

Miguel López is a Spanish physiologist and neuroendocrinology researcher, Full Professor at the Universidade de Santiago de Compostela since 2023, known for work on hypothalamic AMPK and energy balance.

Miguel Martín (oncologist)

Miguel Martín Jiménez is a Spanish medical oncologist specializing in breast cancer, head of medical oncology at the Gregorio Marañón hospital in Madrid since 2009.

Miguel Nicolelis

Miguel Nicolelis (Miguel Angelo Laporta Nicolelis) is a Brazilian neuroscientist known for brain-machine interfaces, including the brain-controlled exoskeleton used at the 2014 World Cup opening ceremony.

Miguel Ondetti

Miguel Angel Ondetti (1930–2004) was an Argentine-born chemist at Squibb who, with David Cushman, discovered captopril, the first orally active ACE inhibitor, sharing the 1999 Lasker Award.

Miguel Soares

Miguel Soares, also known as Miguel P. Soares, is a Portuguese immunologist at the Gulbenkian Institute for Molecular Medicine known for establishing disease tolerance as a defense strategy.