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Life and health

72,234 articles

Muntingia calabura

Muntingia calabura (Jamaican cherry, capulín, kerukup siam) is the sole species of Muntingiaceae genus Muntingia, a 2–12 m Neotropical pioneer tree from Mexico to Bolivia with edible red berries, widely naturalized and studied for flavonoid-rich pharmacological activity.

Muntjac

Muntjac (Muntiacus), barking deer or rib-faced deer, small Asian deer; Reeves' muntjac (Muntiacus reevesi) introduced at Woburn Abbey in 1901 is an invasive species in Britain, reaching 120 deer per km2 and competing with native roe deer.

Mupadolimab

Mupadolimab (CPI-006, CPX-006), Corvus Pharmaceuticals' humanized IgG1κ anti-CD73 antibody, blocks CD73 enzymatic activity and uniquely activates CD73-positive B cells via BCR signaling; studied in phase 1 cancer trials and a discontinued phase 3 COVID-19 trial.

Mupirocin

Mupirocin (pseudomonic acid A, Bactroban, Centany), a topical antibiotic from Pseudomonas fluorescens discovered in 1971, inhibits isoleucyl-tRNA synthetase; used for impetigo and MRSA nasal decolonization, with mupA/mupB-mediated resistance.

Muraena helena

Muraena helena, the Mediterranean moray (Murène commune), is a moray eel of the Muraenidae from the Mediterranean and eastern Atlantic, a nocturnal rocky-reef predator of cephalopods and fish, reaching about 150 cm and 38 years.

Muraglitazar

Muraglitazar (BMS-298585, Pargluva) was a dual PPARα/γ agonist for type 2 diabetes developed by Bristol-Myers Squibb and Merck; FDA approval was declined in 2005 after a meta-analysis showed excess death and cardiovascular events.

Mural cell

A mural cell is a contractile cell that wraps the outside of blood vessels, a collective term covering vascular smooth muscle cells on larger vessels and pericytes on microvessels.

Murat Günel

Murat Günel is a neurosurgeon and geneticist who has led Yale's Department of Neurosurgery since 2014 and studies the genetic causes of brain tumors and vascular disease.

Muredach P. Reilly

Muredach P. Reilly is an Irish-trained cardiologist and physician-scientist at Columbia University, recruited from Penn in 2016, known for identifying the ADAMTS7 gene locus for coronary atherosclerosis.

Murepavadin

Murepavadin (POL7080), a Polyphor cyclic peptide antibiotic and first OMPTA, targets LptD to block LPS transport in Pseudomonas aeruginosa; IV phase 3 development ended in 2019 over kidney injury, inhaled development continues.

Murex

Murex (Linnaeus, 1758) is the type genus of Muricidae, predatory neogastropod sea snails; type species Murex tribulus. Known for spiny shells, the M. trapa mitogenome, and the historic murex purple dye connection.

Muricidae

Muricidae, the murex and rock snails, are a family of carnivorous marine snails with more than 1800 species, known for drilling holes through the shells of prey.

Muricidae molecular phylogeny

Muricidae molecular phylogeny covers DNA-based studies of murex snails, a family of over 1800 carnivorous marine gastropods, which since 2010 have confirmed some subfamilies, shown others polyphyletic, and reduced the accepted subfamilies to nine.

Muridae

Muridae, the murids, is the largest rodent family: Old World mice, rats, and gerbils including Mus and Rattus, with over 1,300 species, about 15 subfamilies, and five major IRBP lineages.

Muriel R. Gillick

Muriel R. Gillick, also known as Muriel Gillick, is an American physician specializing in geriatrics and palliative care at Harvard Medical School, born in 1951.

Murina

Murina (tube-nosed bats, Murininae, Vespertilionidae), genus of small Asian insectivorous bats with tubular nostrils; 46 recognized species, second-largest vespertilionid genus, from Siberia to Australia.

Murine leukemia virus

Murine leukemia virus (MLV, MuLV), a gammaretrovirus of mice discovered by Ludwik Gross in 1951; simple RNA tumor virus encoding only Gag, Pol, Env; basis of first gene therapy vectors.

Muromonab-cd3

Muromonab-CD3 (OKT3, Orthoclone OKT3) is a murine IgG2a anti-CD3 monoclonal antibody, the first FDA-approved therapeutic mAb (1986), used for acute transplant rejection and withdrawn in 2010.

Murphy's sign

Murphy's sign, also called the sonographic Murphy sign, is inspiratory arrest on right upper quadrant palpation indicating acute cholecystitis; described by J. B. Murphy in 1903, specificity 79–96%, sensitivity about 65%.

Murrah buffalo

Murrah buffalo: Indian river buffalo dairy breed from Haryana, name meaning 'curled'; jet-black with spiral horns, 6.9-8.3% milk fat, India's main improver breed exported widely.

Murray A. Mittleman

Murray A. Mittleman is a physician and cardiovascular epidemiologist, professor at the Harvard T.H. Chan School of Public Health and co-developer of the case-crossover study design.

Murray B. Gardner

Murray B. Gardner is an American physician-scientist and virologist known for research on cancer-causing retroviruses of wild mice and cats and on the retroviruses that cause AIDS.

Murray B. Stein

Murray B. Stein is an American psychiatrist and researcher at the University of California San Diego known for research on anxiety disorders, PTSD, and psychiatric genetics.

Murray Barr

Murray Barr, also known as Murray Llewellyn Barr, was a Canadian physician and geneticist who co-discovered the Barr body, the inactivated X chromosome in female cells.

Murray Esler

Murray D. Esler is an Australian cardiovascular neuroscientist and Senior Director of the Baker Heart and Diabetes Institute in Melbourne, known for developing norepinephrine spillover methodology.

Murray F. Brennan

Murray F. Brennan is a New Zealand-born surgical oncologist who chaired surgery at Memorial Sloan Kettering Cancer Center from 1985 to 2006 and built a database of over 9,000 sarcoma patients.

Murray Korc

Murray Korc is an American endocrinologist and pancreatic cancer researcher known for defining the role of growth factors and their receptors, especially EGFR, in pancreatic cancer.

Murray L Whitelaw

Murray L Whitelaw is an Australian professor of biochemistry at the University of Adelaide, best known for 2002 papers identifying the hypoxic switch that regulates hypoxia-inducible factor.

Murray P. Deutscher

Murray P. Deutscher is an American biochemist and professor emeritus at the University of Miami whose laboratory identified several bacterial ribonucleases, including RNase T, D, and PH.

Murray Rabinowitz

Murray Rabinowitz (1927–1983) was an American physician-biochemist at the University of Chicago known for work on mitochondrial molecular biology and cardiac hypertrophy, elected to the National Academy of Sciences in 1983.