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Life and health

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Odesivimab

Odesivimab (REGN3471) is a non-neutralizing human IgG1 antibody against Ebola virus glycoprotein, one of three components of Inmazeb (REGN-EB3), FDA-approved October 14, 2020 for Zaire ebolavirus infection; it kills infected cells via FcγRIIIa effector signaling and also binds soluble glycoprotein.

Odevixibat

Odevixibat (Bylvay) is an oral ileal bile acid transporter inhibitor by Albireo/Ipsen treating cholestatic pruritus in PFIC (approved EU/US 2021) and Alagille syndrome (US 2023), acting locally in the gut.

Odinarchaeota

Odinarchaeota, formally Candidatus Odinarchaeota, is a candidate phylum of Asgard archaea known only from reconstructed genomes, never cultured or imaged. Named in 2017 from Yellowstone hot springs, it has the smallest genomes among Asgard archaea.

Odocoileus

Odocoileus is a North American deer genus (Rafinesque, 1832) holding the white-tailed deer and mule/black-tailed deer, defined by their inter-species hybridization, chronic wasting disease susceptibility, and huge ecological and economic roles.

Odonata

Odonata, the insect order of dragonflies and damselflies (Anisoptera, Zygoptera, Anisozygoptera), about 6,442 species with a 320-million-year fossil record; aquatic larvae, top predators, key freshwater bioindicators, 16% threatened per IUCN 2021.

Odontesthes bonariensis

Odontesthes bonariensis, the pejerrey or Argentinian silverside, is an Atherinopsidae fish of the Río de la Plata basin, key in Argentine fisheries, with temperature-dependent sex determination and aquaculture since 1904.

Odonto-onycho-dermal dysplasia

Odonto-onycho-dermal dysplasia (OODD, OMIM 257980) is a rare autosomal recessive WNT10A ectodermal dysplasia with severe tooth agenesis, cone-shaped teeth, nail dystrophy, palmoplantar hyperkeratosis, and variable sweating changes.

Odontoblast

Odontoblast: dentin-forming cell lining the tooth pulp cavity, derived from neural crest mesenchyme; induced by inner enamel epithelium, secretes predentin, forms sclerotic and reparative dentin, and acts in pulp sensory defense.

Odontochondrodysplasia

Odontochondrodysplasia (ODCD, Goldblatt syndrome, OMIM 184260) is a rare autosomal recessive skeletal dysplasia with dentinogenesis imperfecta, short stature, joint laxity, and platyspondyly, caused by hypomorphic TRIP11 or MIA3 variants.

Odontodactylus scyllarus

Odontodactylus scyllarus, the peacock mantis shrimp, is an Indo-West Pacific smasher stomatopod striking at over 20 m/s with forces up to 1501 N, and has 12 color photoreceptors plus dynamic polarization vision.

Odontogenesis imperfecta

Odontogenesis imperfecta (ODI) is a hereditary tooth-structure disturbance, a generalized genetic defect of enamel and dentine formation; also a former MeSH heading (1965-93) for odontodysplasia and ICD-11 code LA30.9.

Odontoidectomy

Odontoidectomy is a neurosurgical procedure that removes the odontoid process of the second cervical vertebra to relieve compression of the brainstem and upper spinal cord.

Odontology

Odontology (ISSN 1618-1247) is a peer-reviewed English dentistry and craniofacial research journal, official journal of the Society of the Nippon Dental University, published by Springer since 2001 as successor to Shigaku; MEDLINE-indexed, 2025 impact factor 2.6.

Odontometry

Odontometry is the measurement of tooth characteristics (MeSH D009811), covering mesiodistal and buccolingual crown dimensions used in orthodontics, endodontic working-length determination, and forensic estimation of sex, age, and population affinity.

Odontophrynus

Odontophrynus (escuerzos), a genus of 11 semi-fossorial toad-like frogs (Odontophrynidae) from southern and eastern South America, famous for diploid-tetraploid cryptic species in the O. americanus complex.

Odorant-binding protein

Odorant-binding proteins (OBPs), including pheromone-binding proteins (PBPs), are small soluble proteins in insect sensillar lymph and vertebrate nasal mucus that bind and transport hydrophobic odorants to olfactory receptors; first identified in 1981 in Antheraea polyphemus.

Odorrana

Odorrana (odorous frogs, 臭蛙属) is a ranid frog genus of about 70 stream-dwelling species across East and Southeast Asia, established 1990, type species O. margaretae, with karst-endemic and antimicrobial-peptide members.

Odronextamab

Odronextamab (REGN1979, Ordspono) is Regeneron's fully human IgG4 CD20 x CD3 bispecific antibody for relapsed/refractory follicular lymphoma and DLBCL; EU conditional approval August 2024, FDA complete response letters.

Odulimomab

Odulimomab (anti-LFA1, antibody 25.3) is a murine IgG1 monoclonal antibody against human CD11a, the LFA-1 alpha chain; the first LFA-1/ICAM-1 antibody tested clinically, in bone marrow and kidney transplant induction.

OE19

OE19 (OE-19, JROECL19, CVCL_1622) is a human esophageal adenocarcinoma cell line established in 1993 from a 72-year-old man, HER2/ERBB2-amplified, lapatinib-sensitive, microsatellite stable, and distributed by ECACC and DSMZ.

OE33

OE33 (OE-33, JROECL33, CVCL_0471) is a human esophageal adenocarcinoma cell line from a 73-year-old woman's Barrett-associated lower-esophagus tumor, microsatellite stable, TP53-mutant, hyperploid, used widely in EAC research and xenografts.

Oecanthidae

Oecanthidae, the tree crickets and relatives, is a family of true crickets (Grylloidea) redefined in 2022 as a fifth family, sister to Gryllidae, with four subfamilies, about 1400 species, and a Lower Cretaceous origin near 130 Mya.

OECD Pesticide Programme

The OECD Pesticide Programme harmonizes testing and assessment of agricultural pesticides among OECD countries, promoting work sharing and risk reduction while national regulators keep final approval authority.

Oecologia

Oecologia (ISSN 0029-8549 print, 1432-1939 online) is a Springer ecology journal published since 1968 with the International Association for Ecology, MEDLINE-indexed from 2003, impact factor 2.5 (2025).

Oecomys

Oecomys (arboreal rice rats), Thomas 1906, a genus of arboreal Sigmodontinae rodents from Panama to Argentina; most speciose Oryzomyini genus, 17-24 species, high karyotypic diversity 2n=54-86, many cryptic species complexes.

Oecophoridae

Oecophoridae (concealer moths, oecophorid moths), family Bruand 1851 of Gelechioidea moths; about 3,400 species, mostly Australian; subfamilies Pleurotinae and Oecophorinae; sister group Xyloryctidae.

Oedema of eyelid

Oedema of eyelid (eyelid edema, ICD-11 NA06.02) is fluid-driven eyelid swelling from allergic, infectious, inflammatory, drug, traumatic, or systemic causes; orbital cellulitis is the key dangerous differential.

Oedema of larynx

Oedema of larynx (laryngeal edema, ICD-11 CA0H.3, ICD-10 J38.4) is fluid accumulation in laryngeal tissue from anaphylaxis, angioedema, infection, intubation injury, or radiotherapy, causing hoarseness and potentially fatal airway obstruction.

Oedema of legs

Oedema of legs (lower extremity oedema, ICD-11 MG29.01) is excess interstitial fluid causing leg swelling; causes include heart, kidney, liver failure, venous disease, DVT, and drugs such as amlodipine.

Oedemeridae

Oedemeridae, the false blister beetles (pollen-feeding beetles), is a worldwide Tenebrionoidea beetle family of about 100 genera; soft-bodied flower beetles whose cantharidin blisters skin and whose larvae bore in stems or wood.