edgepedia

Life and health

72,234 articles

Patrick Rossignol

Patrick Rossignol (born 1969) is a French nephrologist, professor of therapeutics, and hypertension specialist who led the Nancy Inserm clinical investigation center before moving to Monaco in 2022.

Patrick Ryan Potts

Patrick Ryan Potts is a cancer biologist known for discovering MAGE-RING ubiquitin ligase complexes; since 2020 he has led Amgen's Induced Proximity Platform, developing targeted protein degradation drugs.

Patrick S. Kamath

Patrick S. Kamath is a transplant hepatologist and professor of medicine at Mayo Clinic in Rochester, Minnesota, known as co-developer of the MELD score used worldwide for liver allocation.

Patrick S. Moore

Patrick S. Moore is a physician-scientist at the University of Pittsburgh who, with his wife Yuan Chang, discovered the cancer viruses KSHV and Merkel cell polyomavirus.

Patrick S. Parfrey

Patrick S. Parfrey is an Irish-born nephrologist and clinical epidemiologist at Memorial University of Newfoundland, known for research on kidney disease and cardiovascular complications in dialysis patients.

Patrick S. Schnable

Patrick S. Schnable is an American plant geneticist at Iowa State University who co-led the team that published the maize reference genome in 2009 and directs the Plant Sciences Institute.

Patrick Schöffski

Patrick Schöffski is a German medical oncologist and full professor at KU Leuven who heads medical oncology at University Hospitals Leuven and sarcoma drug trials.

Patrick Seale

Patrick Seale is an American-trained biologist and professor of cell and developmental biology at the University of Pennsylvania, known for work on brown fat and muscle satellite cells.

Patrick Soon-Shiong

Patrick Soon-Shiong, born 1952 in Port Elizabeth, South Africa, is a surgeon-scientist and billionaire who invented Abraxane, founded the NantWorks healthcare network and ImmunityBio (maker of Anktiva), and owns the Los Angeles Times and a Lakers stake.

Patrick Steptoe

Patrick Christopher Steptoe was a British gynecologist who, with physiologist Robert Edwards, developed in vitro fertilization into a clinical treatment, culminating in Louise Brown's 1978 birth.

Patrick T. O’Gara

Patrick T. O'Gara is an American cardiologist at Brigham and Women's Hospital and Harvard Medical School, known for valvular and aortic heart disease and for chairing national cardiovascular guidelines.

Patrick Tan

Patrick Tan Boon Ooi is a Singapore physician-scientist known for molecular classification of gastric cancer, Dean of Duke-NUS Medical School, and Executive Director of PRECISE, Singapore's national precision medicine program.

Patrick Vallance

Patrick Vallance (Lord Vallance) is a British physician and former GSK R&D president who was UK Government Chief Scientific Adviser 2018-2023, co-chaired SAGE during COVID-19, testified to the Covid-19 Inquiry, and later served as science minister.

Patrick W. Mantyh

Patrick W. Mantyh is a neuroscientist and pharmacologist at the University of Arizona who built the first animal model of bone cancer pain and showed in 2000 that osteoprotegerin blocks it.

Patrick W. Serruys

Patrick W. Serruys, also known as Patrick Serruys, is a Belgian interventional cardiologist who introduced coronary stenting in the Netherlands in 1986 and led the ABSORB bioresorbable scaffold program.

Patrick Y. Wen

Patrick Y. Wen, also known as Patrick Wen, is a neuro-oncologist who directs the Neuro-Oncology Division at Brigham and Women's Hospital and is Professor of Neurology at Harvard Medical School.

Patrik Ernfors

Patrik Ernfors is a neuroscientist and Professor of Tissue Biology at Karolinska Institutet in Stockholm, known for molecular classification of sensory neurons and The Brain Prize 2026.

Patrik Nosil

Patrik Nosil, born 1975, is a Canadian evolutionary biologist and Director of Research at France's CNRS, known for studies of ecological speciation and adaptation in Timema stick insects.

Patrik Rorsman

Patrik Rorsman, born in 1959, is a Swedish diabetes and islet physiologist who is Professor of Diabetic Medicine at Oxford and also a professor at the University of Gothenburg.

Patrik Verstreken

Patrik Verstreken (born 1974) is a Belgian molecular neurobiologist who studies how synapses work and break down in Parkinson's disease, directing the VIB-KU Leuven Center for Brain & Disease Research.

Patritumab

Patritumab (AMG 888, U3-1287) is a fully human IgG1 monoclonal antibody against HER3 (ERBB3) that blocks ligand binding and internalizes the receptor; its naked-antibody phase 3 program was halted, and it now serves as the backbone of the ADC patritumab deruxtecan (HER3-DXd).

Patrizia Farci

Patrizia Farci is an Italian physician-scientist who studies viral hepatitis, trained at the University of Cagliari, and has led the Hepatic Pathogenesis Section at NIH's NIAID since 2010.

PATS trial

PATS (Pediatric Adenotonsillectomy Trial for Snoring), NCT02562040, was an NHLBI-funded US randomized trial of 459 children aged 3-12.9 with mild sleep-disordered breathing comparing adenotonsillectomy with watchful waiting; cognition did not differ, but behavior, sleep, blood pressure, and progression improved.

Patterdale Terrier

Patterdale Terrier, a small black Fell Terrier-type working terrier from England's Lake District, bred to go to ground after foxes; UKC-recognized January 1, 1995, 10-15 inches tall, spannable chest, not AKC-recognized.

Pattern hair loss

Pattern hair loss, or androgenetic alopecia, male pattern baldness / female pattern hair loss, is a common genetically and androgen (DHT) driven follicle miniaturization disorder affecting up to 80% of men and 50% of women, treated with minoxidil and finasteride.

Pattern recognition receptor

Pattern recognition receptors (PRRs) are germline-encoded innate immune sensors detecting PAMPs and DAMPs. Families include TLRs, CLRs, NLRs, RLRs, and cGAS; concept proposed by Janeway in 1989, validated by Toll in 1996, honored by the 2011 Nobel Prize.

Patterned and diffuse alopecia areata

Patterned and diffuse alopecia areata are non-patchy forms of the autoimmune hair loss alopecia areata, covering the band-like ophiasis and sisaipho patterns and the diffuse variants that thin across the scalp.

Patterns in nature

Patterns in nature: regularities such as animal stripes, shell spirals, branching, and phyllotaxis, explained mainly through Turing's 1952 reaction-diffusion theory, Wolpert's positional information, and mechanical and mass-conserving models.

Patterson-Stevenson-Fontaine syndrome

Patterson-Stevenson-Fontaine syndrome (split foot deformity with mandibulofacial dysostosis, OMIM 183700) is a very rare autosomal dominant acrofacial dysostosis: retrognathism, cleft palate, ear anomalies, split foot, toe syndactyly; fewer than ten patients described.

Patulin

Patulin (PAT), a polar lactone mycotoxin from Penicillium, Aspergillus, and Byssochlamys molds, contaminates apples and apple juice; regulated at 50 µg/kg by FDA and Codex, with JECFA PMTDI 0.4 µg/kg bw.