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Life and health

72,234 articles

Sebastes spp

Sebastes spp, the redfishes and rockfishes, a genus of about 110 livebearing scorpaenid fishes, mostly Pacific, with four North Atlantic commercial species (S. norvegicus, S. mentella, S. fasciatus, S. viviparus), extreme lifespans up to 200+ years, and major trawl fisheries.

Sebastiaan Luyssaert

Sebastiaan Luyssaert is a forest ecologist and land surface modeler at Vrije Universiteit Amsterdam, known for the 2008 finding that old-growth forests keep storing carbon.

Sebastián Amigorena

Sebastian Amigorena is a French immunologist, a CNRS research director at Institut Curie in Paris, known for work on dendritic cell antigen presentation and cancer immunotherapy.

Sebastian Bonhoeffer

Sebastian Bonhoeffer is a German-born theoretical biologist who has been professor of theoretical biology at ETH Zurich since 2005 and directs the Collegium Helveticum, modeling infectious disease dynamics.

Sebastian Deindl

Sebastian Deindl is a structural biologist and molecular biophysicist, professor at Uppsala University and, since 2026, Humboldt Professor at Tübingen, known for resolving how chromatin remodelers step and slide molecule by molecule.

Sebastian Jessberger

Sebastian Jessberger, born 1974 in Mannheim, Germany, is a neuroscientist who directs the Brain Research Institute at the University of Zurich and studies neural stem cells.

Sebastian Klinge

Sebastian Klinge is a structural biologist at Rockefeller University who studies how eukaryotic cells assemble ribosomes, and who in 2011 solved the first atomic structure of a eukaryotic large ribosomal subunit.

Sebastian L. Johnston

Sebastian L. Johnston, born 1959, is a British physician-scientist and Professor of Respiratory Medicine at Imperial College London who established the viral cause of asthma attacks.

Sebastian Lourido

Sebastian Lourido is an American parasitologist, associate professor of biology at MIT and a Whitehead Institute member, known for genome-wide CRISPR screens of Toxoplasma gondii.

Sebastian Schneeweiß

Sebastian Schneeweiß is a German-trained physician and pharmacoepidemiologist who is Professor at Harvard Medical School and Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital in Boston.

Sebastian Seung

Sebastian Seung, also known as H. Sebastian Seung, is a computational neuroscientist at Princeton University known for connectomics and for creating the crowd-sourced brain-mapping platforms EyeWire and FlyWire.

Sébastien Gagneux

Sébastien Gagneux is a Swiss infectious-disease researcher who leads the Tuberculosis Ecology and Evolution group at Swiss TPH and is a professor at the University of Basel.

Sebelipase alfa

Sebelipase alfa (Kanuma) is a recombinant human lysosomal acid lipase enzyme replacement therapy for LAL deficiency, including Wolman disease, produced in transgenic hen egg white; EU-approved August 2015, FDA December 2015.

Sebocystomatosis

Sebocystomatosis, also called steatocystoma multiplex (OMIM 184500), is a rare autosomal dominant disorder with KRT17 mutations causing multiple benign sebum-filled dermal cysts on the chest, axillae, and upper arms, typically appearing at puberty.

Sebocyte

Sebocyte: the specialized lipid-producing epithelial cell of the sebaceous gland (sebaceous gland cell), releasing sebum by holocrine secretion. Defined by androgen/PPARγ regulation, wax ester and sapienic acid output, and roles in acne.

Seborrheic keratosis

Seborrhoeic keratosis (seborrheic keratosis, senile wart, basal cell papilloma) is a benign keratinocyte skin growth, extremely common after age 60, diagnosed clinically and by dermoscopy, treated by cryotherapy, curettage, or lasers.

Seborrhoea

Seborrhoea (seborrhea, oily skin, hypersteatosis) is excessive sebum secretion causing greasy skin, ICD-11 ED91.2. Distinct from seborrhoeic dermatitis; linked to acne, acromegaly, and Parkinson disease.

Seborrhoeic dermatitis

Seborrhoeic dermatitis, also called seborrheic eczema, is a common, relapsing eczema affecting oily areas like the scalp, face, and trunk, linked to Malassezia yeast and managed rather than cured.

Seborrhoeic dermatitis of the scalp

Seborrhoeic dermatitis of the scalp (ICD-11 EA81.1; dandruff is its mild form) is a chronic relapsing inflammatory scalp disease linked to Malassezia yeasts, sebum, and immune dysregulation, treated with antifungal and anti-inflammatory shampoos.

Sec-independent periplasmic protein translocase TatC

TatC is the six-transmembrane-helix receptor protein of the bacterial twin-arginine translocation (Tat) pathway, recognizing twin-arginine signal peptides and forming the TatBC core complex that transports folded proteins.

Sec-independent protein translocase protein TatB

TatB (Sec-independent protein translocase protein TatB, E. coli tatB, P69425) is a 171-residue single-pass membrane protein that with TatC forms the Tat receptor binding twin-arginine signal peptides and proofreads substrate folding; absent from most Gram-positive bacteria.

Sec16, central conserved domain

Sec16 central conserved domain (CCD), the ~400-amino-acid folded core of the Sec16 scaffold protein at ER exit sites; binds Sec13, Sec24, and Sec31, forms a 2:2 Sec16-Sec13 tetramer, and is conserved across eukaryotes though not essential for viability.

SEC16A

SEC16A (KIAA0310, Sec16L), human gene on 9q34.3 encoding a 2357-aa scaffold protein organizing ER exit sites and COPII ER-to-Golgi transport; paralog SEC16B; linked to neurodevelopmental disorder and chronic pancreatitis.

Sec63 domain

Sec63 domain (Pfam PF02889, InterPro IPR004179), also called the Brl domain, named after yeast Sec63/NPL1; a conserved eukaryotic domain required for assembly of functional ER translocons, also found in helicases BRR2 and HFM1.

Sec7 domain

Sec7 domain, also called SEC7 homology domain, is a roughly 200-residue catalytic GEF domain for ARF small GTPases, named after yeast SEC7; it has ten alpha-helices, a glutamic-finger catalytic glutamate, and is targeted by brefeldin A.

Secale

Secale is a Poaceae genus of Triticeae grasses including cultivated rye (Secale cereale), domesticated from weedy rye, grown on 4.1 million ha mostly in northeastern Europe, high in dietary fiber, and a gluten and allergen source.

Secbumeton

Secbumeton (etazine, isobumeton) is an obsolete methoxytriazine herbicide, C10H19N5O, CAS 26259-45-0, first reported 1966 by Ciba-Geigy; photosystem II inhibitor formerly used on grapes, alfalfa, and sugarcane, now not approved in the EU.

Seckel syndrome

Seckel syndrome (bird-headed dwarfism, OMIM 210600) is a rare autosomal recessive microcephalic primordial dwarfism with prenatal-onset short stature, bird-headed facies, and intellectual disability, caused by genes such as ATR, CENPJ, and CEP152.

Secnidazole

Secnidazole (Solosec) is a long-half-life 5-nitroimidazole antimicrobial given as a single 2 g oral dose for bacterial vaginosis and trichomoniasis; FDA-approved 2017 (BV) and 2021 (trichomoniasis), similar to metronidazole, possibly inferior to ornidazole.

Secobarbital

Secobarbital, known as quinalbarbitone in Britain and sold as Seconal in red capsules, is a short-acting barbiturate sleep medication discontinued in the United States in 2020.