72,234 articles
Superovulation
Superovulation (multiple ovulation induction, ovarian hyperstimulation) is hormone treatment, mainly FSH or equine chorionic gonadotropin, making a female ovulate many eggs; used in livestock embryo transfer and human IVF, first described by Pincus in 1940.
Superoxide dismutase
Superoxide dismutase (SOD, EC 1.15.1.1), metalloenzyme family converting superoxide to oxygen and hydrogen peroxide; discovered 1969 by McCord and Fridovich in erythrocuprein; isoforms CuZnSOD, MnSOD, EC-SOD.
Superoxide dismutase, Nickel-type
Nickel-type superoxide dismutase (NiSOD, sodN) is a nickel-cofactored bacterial enzyme, discovered in Streptomyces in 1996, that detoxifies superoxide via a Ni(III)/Ni(II) nickel-hook active site, mainly in marine cyanobacteria and actinomycetes.
Superparamagnetic iron oxide nanoparticles
Superparamagnetic iron oxide nanoparticles (SPIONs) are nanoscale iron oxide crystals, usually magnetite or maghemite, coated for biocompatibility and used as MRI contrast agents, drug carriers, and heat mediators in magnetic hyperthermia.
Supersaurus
Supersaurus ("super lizard"), type species S. vivianae, is a giant diplodocid sauropod dinosaur from the Late Jurassic Morrison Formation of Colorado, named by Jensen in 1985; 33–39 m long, 30–44 tons, with Dystylosaurus and Dinheirosaurus as synonyms.
Supervised exercise therapy
Supervised exercise therapy (SET) is structured exercise prescribed under professional supervision, recommended as first-line treatment for leg pain from peripheral artery disease, typically treadmill walking for 3 to 6 months.
Supination
Supination: rotation turning the palm forward or upward at the forearm (radius around ulna, 80–90° range; supinator and biceps), or adduction plus inversion raising the foot's arch; opposite of pronation.
Supine position
Supine position: lying flat on the back, face up (decúbito supino). The most common surgical position; highest cardiac output and lowest vascular resistance of compared body positions; arms kept under 90 degrees abduction.
SUPPORT trial (NCT00233324)
SUPPORT (NCT00233324), Surfactant Positive Airway Pressure and Pulse Oximetry Trial, a 2x2 factorial US trial of 1,316 infants born at 24-27 weeks: early CPAP versus surfactant and 85-89% versus 91-95% oxygen targets; lower targets cut severe ROP but raised mortality.
SUPPORT trial (NCT06264050)
SUPPORT (NCT06264050) is a single-group pre-post observational study at IRCCS San Camillo, Venice, testing whether a Psychological Support Group changes anxiety (STAI Y2), depression (BDI-II), coping (COPE-NVI 25), and outcomes (CORE-OM) in 19 neurorehabilitation inpatients.
Supported Employment
Supported employment (Individual Placement and Support, IPS) is an evidence-based vocational rehabilitation model that places people with severe mental illness or other disabilities in competitive jobs first, with concurrent treatment and time-unlimited on-the-job support, outperforming train-then-place programs in employment outcomes.
Supporting cell (sensu Nematoda and Protostomia)
Supporting cell (sensu Nematoda and Protostomia) is a Cell Ontology term for non-neuronal support cells of nematode and protostome sensory organs, notably C. elegans sheath, socket, and GLR cells forming sensillum channels.
Supporting cell (sensu Nematoda)
Supporting cells (sensu Nematoda) are the glial cells of nematodes, chiefly C. elegans: 56 per hermaphrodite, comprising 24 sheath, 26 socket, and 6 GLR cells that ensheath sensory neuron endings and form sensillum channels.
Supportive and psychosocial care in Duchenne muscular dystrophy
Supportive and psychosocial care in Duchenne muscular dystrophy covers cognition, behavior, education, mental health, transition to adult life, and family caregiver support rather than drug treatment.
Supportive periodontal therapy
Supportive periodontal therapy, also called periodontal maintenance, is the long-term recall phase of dental care in which patients treated for periodontitis attend regular visits to keep the disease stable.
Supportive psychotherapy
Supportive psychotherapy is a psychotherapy that strengthens coping, self-esteem, and adaptive skills rather than changing personality, and is the most widely practiced therapy among psychiatrists.
Suppository
Suppository: solid single-dose medication inserted rectally, vaginally, or urethrally; melts or dissolves to release drug locally or systemically, partially bypassing liver first-pass metabolism; fatty or hydrophilic bases.
Suppressed lactation
Suppressed lactation: deliberate prevention or cessation of milk production after childbirth in non-breastfeeding women, also called lactation inhibition. Managed physiologically (breast support, comfort expression) or with drugs such as bromocriptine and cabergoline; distinct from agalactia (JB46.3).
Suppression of apoptosis
Suppression of apoptosis (Reactome R-HSA-9635465) is the inhibition of programmed cell death, mainly via anti-apoptotic BCL-2 family proteins and IAPs; it underlies cancer immune evasion and is reversed therapeutically by venetoclax.
Suppressive antiretroviral therapy
Suppressive antiretroviral therapy (ART) is the combination of antiretroviral drugs that keeps a person's HIV viral load undetectable, halting disease progression and preventing sexual transmission of the virus.
Suppressor Genes
Suppressor genes are genes carrying a suppressor allele or mutation that cancels the effect of a previous mutation, restoring the wild-type phenotype; distinct from tumor suppressor genes.
Suppressor of fused
Suppressor of fused (SUFU, Sufu) is a conserved negative regulator of Hedgehog signaling that sequesters GLI1-3 transcription factors in the cytoplasm; discovered in Drosophila as a fused suppressor, essential in mouse development, a tumor suppressor linked to medulloblastoma.
Suprabasal cell
Suprabasal cell: epithelial cell in layers above the basal layer of stratified or pseudostratified epithelia (skin, esophagus, airway, cornea); arises from basal cells, expresses differentiation keratins, and is committed to terminal differentiation.
Supracervical hysterectomy
Supracervical hysterectomy is an operation that removes the uterine corpus while leaving the cervix in place, used mainly for benign disorders such as fibroids and abnormal bleeding.
Suprachiasmatic nucleus
Suprachiasmatic nucleus (SCN), hypothalamic master circadian pacemaker above the optic chiasm, ~20,000 neurons, intrinsic period ~24.2 h, light-entrained via the retinohypothalamic tract, synchronizes peripheral clocks and melatonin rhythms.
Supraclavicular brachial plexus block
The supraclavicular brachial plexus block, or supraclavicular block, is a regional anesthesia technique injecting local anesthetic above the clavicle to numb the arm and shoulder.
Supraclavicular lymph nodes
Supraclavicular lymph nodes (nodi lymphoidei supraclaviculares): 4-12 nodes above the clavicle draining breast, lung, esophagus, and abdomen; the left Virchow node (Troisier sign) signals metastatic cancer in 54-85% of enlargements.
Supracondylar fracture of humerus
Supracondylar humerus fracture, pediatric distal humerus fracture above the elbow, most common childhood elbow injury, Gartland types I-IV, treated by casting or closed reduction with percutaneous pinning.
Supraglottoplasty
Supraglottoplasty is a surgical procedure in otolaryngology that removes or reduces abnormal supraglottic laryngeal tissue to relieve the airway obstruction caused by laryngomalacia, the most common cause of stridor in infants.
Supramalleolar osteotomy
Supramalleolar osteotomy is a joint-preserving orthopedic procedure that cuts and realigns the tibia just above the ankle to shift load onto preserved cartilage in asymmetric ankle arthritis.