edgepedia

Life and health

72,234 articles

Etifoxine

Etifoxine (Stresam) is a non-benzodiazepine, benzoxazine anxiolytic acting on GABA-A receptors and TSPO, authorized in France, Malta, Bulgaria, and Romania, restricted since 2022 for rare severe skin and liver toxicity.

Etimicin

Etimicin (依替米星, antibiotic 89-07, sulfate salt 硫酸依替米星) is a fourth-generation semisynthetic aminoglycoside antibiotic developed in China from gentamicin C1a, approved 1997 and launched 1999, with lower ototoxicity and nephrotoxicity than gentamicin or amikacin.

Etiology

Etiology, from Greek aitia (cause), is the cause or origin of disease and the medical science studying disease causes, spanning microbial, genetic, environmental, and lifestyle factors and their pathogenesis.

Etirinotecan pegol

Etirinotecan pegol (NKTR-102, brand name Onzeald) is an investigational, long-acting PEGylated conjugate of the topoisomerase I inhibitor irinotecan, designed to release irinotecan slowly for sustained tumor exposure.

ETIS study

ETIS (Endovascular Treatment in Ischemic Stroke), NCT03776877, is a French prospective multicenter observational registry of thrombectomy for acute ischemic stroke, reporting real-world outcomes, complications, and reperfusion strategy effects.

Etizolam

Etizolam is a thienodiazepine (thienotriazolodiazepine) CNS depressant acting at the GABA_A benzodiazepine site, 6-10 times more potent than diazepam. Approved in Italy, Japan, and India; UN Schedule IV since 2020; US Schedule I since 2023, permanent 2026.

Etlingera

Etlingera (aromatic ginger) is a genus of about 150 Zingiberaceae herbs from the Indomalayan realm; torch ginger (E. elatior) is used as spice, medicine, and ornamental, with about 410 phytocompounds reported.

Etlingera elatior

Etlingera elatior, commonly known as torch ginger (Malay: bunga kantan), is a large ginger-family plant native to Southeast Asia, grown for its edible flower buds and showy blooms.

Etodolac

Etodolac (Lodine) is a pyranocarboxylic acid NSAID approved in the US in 1991 for osteoarthritis, rheumatoid arthritis, and acute pain, distinguished by modest COX-2 selectivity and a relatively favorable gastrointestinal tolerability profile.

Etofenprox

Etofenprox (ethofenprox, MTI 500, TREBON) is an ether-linkage pyrethroid-type insecticide developed by Mitsui Toatsu, introduced in Japan in 1987, with low fish and mammalian toxicity, WHO class U, used on rice and for mosquito vector control.

Etofesalamide

Etofesalamide (乙氧苯柳胺, trade name Aidite) is a Chinese Category 1 non-steroidal topical anti-inflammatory and anti-allergic drug approved for chronic eczema and neurodermatitis, marketed as a 5% ointment by Shandong Xinhua Pharmaceutical since 1997.

Etomidate

Etomidate, also marketed as Hypnomidate, is an intravenous sedative-hypnotic drug introduced in 1972 to induce general anesthesia, valued for hemodynamic stability but limited by adrenal cortisol suppression.

Etoposide

Etoposide (VP-16), a semisynthetic podophyllotoxin derivative topoisomerase II inhibitor, treats small cell lung and testicular cancer; FDA approved 1983, causes DNA breaks, myelosuppression, and is given by slow IV infusion.

Etoricoxib

Etoricoxib (Arcoxia) is a selective COX-2 inhibitor NSAID approved in Europe for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute gout, and acute pain; never FDA-approved, with ~20-hour half-life and diclofenac-comparable cardiovascular risk.

Etorphine

Etorphine, also known as M99, is a semi-synthetic opioid estimated 5,000 to 10,000 times more potent than morphine, used to immobilize elephants, rhinoceros, and other zoo and wild animals.

Etoxazole

Etoxazole (CAS 153233-91-1), a diphenyl oxazoline selective miticide, IRAC Group 10B, inhibits chitin synthesis in mite eggs and juveniles; EU approval renewed to 2028 as candidate for substitution.

Etranacogene dezaparvovec drlb

Etranacogene dezaparvovec drlb (HEMGENIX) is an AAV5-based gene therapy by CSL Behring, approved in 2022 as a single infusion to treat hemophilia B in adults.

Etrasimod

Etrasimod (Velsipity) is an oral, once-daily selective S1P1,4,5 receptor modulator by Pfizer/Arena, FDA-approved October 2023 for moderately to severely active ulcerative colitis, proven in the phase 3 ELEVATE UC trials.

Etridiazole

Etridiazole (Terrazole), a thiadiazole Oomycete fungicide acting via mitochondrial phospholipid hydrolysis (FRAC 14); EU approval expired 2021, MRLs cut to 0.01 mg/kg in 2024; WHO Class III.

Etrimfos

Etrimfos (CAS 38260-54-7), also SAN 197 I, is an obsolete heterocyclic organophosphorus insecticide and acaricide introduced in 1972, with JMPR ADI 0.003 mg/kg bw, not approved in the EU since Regulation 2076/2002.

Etrog (אֶתְרוֹג)

Etrog (אֶתְרוֹג), Hebrew for citron (Citrus medica), the yellow thick-rinded citrus used as one of the Four Species with the lulav on Sukkot; ungrafted, blemish-free fruits can sell for $100 or more.

Etrolizumab

Etrolizumab (rhuMAb beta7, PRO145223) is a Roche humanized anti-beta7 monoclonal antibody targeting alpha4beta7 and alphaEbeta7 integrins for IBD; its phase 3 program failed key endpoints and it was not approved.

Etruscan shrew

Etruscan shrew (Suncus etruscus), also white-toothed pygmy shrew or Savi's pygmy shrew: smallest living mammal by mass at 1.8–3 g, 35–48 mm long, with heart rates up to 1500 bpm, ranging from Iberia to Borneo.

ETS family

ETS family: E26 transformation-specific transcription factors, ~28 human members defined by an ~85-amino-acid winged helix-turn-helix ETS domain binding GGAA/T motifs; roles in hematopoiesis, immunity, and cancer fusions such as TMPRSS2–ERG and EWS–FLI1.

ETS1

ETS1 is a human gene on chromosome 11 that encodes Ets-1, the founding member of the Ets transcription factor family, known for roles in angiogenesis, development, and cancer metastasis.

ETS2

ETS2 (ETS proto-oncogene 2, HGNC:3489) is a human chromosome 21q22.2 gene encoding an ETS-family transcription factor and proto-oncogene regulating development, apoptosis, and telomerase; distinct from Euro Truck Simulator 2 and the EU carbon market ETS2.

ETSACPDSFP trial

ETSACPDSFP (NCT07387536) is a recruiting Phase 4, single-arm Mexican trial testing Improscar Stick 50, silicone with SPF 50, on scar quality after upper blepharoplasty using Vancouver and POSAS scales over 3 months.

Ettore Appella

Ettore Appella, born in Italy in 1933, is an Italian-born scientist at the National Cancer Institute who helped identify the p53 tumor suppressor protein and discovered the Wip1 phosphatase.

Ettore Marchiafava

Ettore Marchiafava (1847–1935) was an Italian physician and malariologist in Rome who, with Angelo Celli, named the malaria parasite Plasmodium and helped found the Italian school of malariology.

Etuvetidigene autotemcel

Etuvetidigene autotemcel (Waskyra, etu-cel) is an autologous lentiviral HSPC gene therapy for Wiskott-Aldrich syndrome, approved by FDA December 9, 2025 and EMA January 9, 2026, marketed by Fondazione Telethon.