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Life and health

72,234 articles

HAICI trial

HAICI (NCT06741020), Hepatic Arterial Infusion Chemotherapy and Immunotherapy for Hepatocellular Carcinoma, a phase 1/2 single-arm pilot neoadjuvant trial at Zhejiang Cancer Hospital testing FOLFOX-HAIC plus adebrelimab in resectable BCLC A/B HCC.

Haidong D. Dong

Haidong D. Dong is a physician-scientist and Professor of Immunology at Mayo Clinic, best known for discovering B7-H1 and showing tumor-cell B7-H1 promotes T-cell apoptosis.

Haifan Lin

Haifan Lin is a stem cell biologist at Yale School of Medicine, founding director of the Yale Stem Cell Center, known for discovering the Piwi gene family and piRNAs.

Haig H. Kazazian

Haig H. Kazazian (1937–2022) was an American human geneticist at Johns Hopkins and Penn who pioneered DNA-based prenatal diagnosis of hemoglobin disorders and showed that transposable elements cause human disease.

Hailey-Hailey disease

Hailey-Hailey disease (benign familial pemphigus, OMIM 169600) is a rare autosomal dominant genodermatosis caused by ATP2C1 mutations, causing recurrent erosive plaques in skin folds, onset in adulthood, no cure.

Hailing Jin

Hailing Jin is a plant molecular geneticist at UC Riverside who discovered cross-kingdom RNA interference and was elected to the National Academy of Sciences in 2025.

Haim Aviv

Haim Aviv is an Israeli molecular biologist and biotechnology entrepreneur known for his 1970s work on globin messenger RNA at the Weizmann Institute and NIH, who founded Bio-Technology General in 1980.

Haim Sompolinsky

Haim Sompolinsky, born 1949 in Copenhagen, is an Israeli computational neuroscientist, professor emeritus at the Hebrew University of Jerusalem and a Harvard professor since 2022, known for spin-glass models of neural memory.

Haim-Munk syndrome

Haim-Munk syndrome (HMS), an autosomal recessive CTSC (cathepsin C) disorder on 11q14, allelic to Papillon-Lefèvre syndrome; features palmoplantar hyperkeratosis, early periodontitis, onychogryphosis, arachnodactyly, acro-osteolysis, pes planus; under 100 cases, mostly Cochin Jewish descendants.

Hair

Hair: keratin filaments grown from skin follicles, cycling through anagen, catagen, and telogen. Covers structure, thermoregulatory evolution of tightly curled scalp hair, variation, and hair-loss treatment.

Hair analysis

Hair analysis is the laboratory measurement of substances incorporated in the hair shaft to assess drug use, nutrition, or exposure over past weeks to months, unlike blood or urine.

Hair cell

Hair cells are the inner ear's mechanosensory receptors, topped with stereocilia; inner hair cells encode sound, outer hair cells amplify it, and mammalian hair cells do not regenerate.

Hair Color

Hair color: natural pigmentation of hair or fur by melanin. Eumelanin gives black/brown, pheomelanin red; MC1R and 200+ variants control it; graying reflects lost melanin production.

Hair follicle

Hair follicle: tube-like skin organ producing hair; over 5 million at birth, 1 million on the scalp. Dermal papilla signals growth, bulge holds stem cells, cycles anagen, catagen, telogen, exogen.

Hair germinal matrix cell

Hair germinal matrix cell (trichocyte, CL:0002562): mitotically active epidermal cell in the hair bulb matrix surrounding the dermal papilla; proliferates during anagen and differentiates into hair shaft and inner root sheath.

Hair loss

Hair loss (alopecia): loss of scalp or body hair from heredity, autoimmunity, stress, drugs, or scarring disease. Key types are androgenetic alopecia, alopecia areata, and telogen effluvium; treatments include minoxidil, finasteride, and JAK inhibitors.

Hair removal

Hair removal is the practice of removing unwanted body hair, categorized into depilation, which removes the hair shaft, and epilation, which removes the root, including waxing, lasers, and electrolysis.

Hair transplantation

Hair transplantation: surgery moving hair follicles from a permanent donor scalp zone to bald areas, treating androgenetic alopecia. Techniques: FUT strip harvesting (1990s) and FUE punch extraction (2000s); donor dominance principle; UK cost £1,000–£30,000.

Hairy cell leukemia

Hairy cell leukemia (HCL, HCL variant) is a rare indolent B-cell leukemia with hairy-appearing cells, BRAF V600E in >95% of classic cases, splenomegaly, pancytopenia, and cladribine-rituximab treatment.

Hairy cell leukemia variant

Hairy cell leukemia variant (HCLv, HCL-v), also called splenic B-cell lymphoma/leukemia with prominent nucleoli in WHO5, is a rare splenic B-cell neoplasm, BRAF V600E-negative, MAP2K1-mutated in about 50%, resistant to purine analog monotherapy, treated with cladribine plus rituximab.

Hairy frog

Hairy frog (Trichobatrachus robustus, also Astylosternus robustus), Central African Arthroleptidae frog; breeding males grow hair-like papillae and it erects claws by breaking toe bones through skin; IUCN Least Concern.

Hairy leukoplakia

Hairy leukoplakia (oral hairy leukoplakia, OHL) is an EBV-caused white patch on the lateral tongue in immunosuppressed people, mainly untreated HIV; a CDC category-B AIDS marker, not premalignant, resolving with antiretroviral therapy.

Hairy root culture

Hairy root culture is a plant biotechnology method in which Agrobacterium rhizogenes transfers Ri plasmid DNA into plant tissue, producing fast-growing, hormone-independent, genetically stable roots.

Haisco oral complement inhibitor (sipcopan succinate)

HSK39297 (琥珀酸思普可泮片, 优可盼; NXP100) is Haisco's once-daily oral complement factor B inhibitor, approved in China in July 2026 for complement inhibitor-naive PNH adults, with IgAN phase 3 and Nuvectis ex-China licensing.

Haiti cholera outbreak

The 2010–2019 Haiti cholera outbreak was Haiti's first cholera epidemic in a century, killing at least 9,789 people after UN peacekeepers' sewage contaminated a river.

Haiwei Song

Haiwei Song is a structural biologist and Research Director at A*STAR's Institute of Molecular and Cell Biology in Singapore, known for the crystal structure of human eRF1.

Haixin Sui

Haixin Sui is a Chinese-born structural biologist at the Wadsworth Center in Albany, New York, who applies cryo-electron tomography to cilia, microtubule doublets, and pathogen complexes.

Haiyuan Yu

Haiyuan Yu is a computational biologist and Tisch University Professor at Cornell University known for building large-scale protein interaction networks of yeasts and humans and adding three-dimensional structural detail to them.

Hajdu-Cheney syndrome

Hajdu-Cheney syndrome (HCS, OMIM 102500, ORPHA955), also called acroosteolysis dominant type or serpentine fibula-polycystic kidney syndrome, is a rare autosomal dominant NOTCH2-related skeletal disorder with acroosteolysis, osteoporosis, and craniofacial anomalies.

Hajime Karasuyama

Hajime Karasuyama (烏山 一) is a Japanese immunologist and physician known for work on B cell development, for showing that basophils drive chronic allergic inflammation, and for identifying STAT3 mutations as the cause of hyper-IgE syndrome.