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Life and health

72,234 articles

Hemopexin

Hemopexin (HPX) is a heme-binding plasma glycoprotein produced mainly by the liver that sequesters free heme with very high affinity and delivers it to the liver, acting as a second-line defense after hemolysis.

Hemophagocytic lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH), including familial HLH and macrophage activation syndrome, is a life-threatening hyperinflammatory cytokine storm syndrome diagnosed by HLH-2004 criteria or HScore, treated with etoposide, steroids, emapalumab, and HSCT, with about 50% adult mortality.

Hemophagocytic syndrome associated with an infection

Infection-associated hemophagocytic syndrome (IAHS), or reactive hemophagocytic syndrome, is secondary hemophagocytic lymphohistiocytosis triggered by a concurrent infection, most often Epstein-Barr virus; diagnosis uses HLH-2004 criteria or HScore, and treatment targets the infectious trigger.

Hemoporfin for injection (Fumeida)

Hemoporfin for injection (Fumeida, 复美达), also called HMME (hematoporphyrin monomethyl ether), is a Chinese class 1.1 photodynamic drug approved in 2016; the first drug worldwide for port-wine stain, given intravenously with 532 nm laser irradiation.

Hemoptysis

Haemoptysis (hemoptysis) is coughing up blood from the lower respiratory tract; 5–14% of cases are life-threatening, usually from bronchial arteries, treated with bronchial artery embolization.

Hemorrhagic fever-renal syndrome

Hemorrhagic fever with renal syndrome (HFRS), also called Korean hemorrhagic fever or epidemic hemorrhagic fever, is a rodent-borne hantavirus disease of Europe and Asia causing fever, hemorrhage, and acute kidney injury, with case fatality from under 1% (Puumala) to 15% (Hantaan).

Hemorrhoid

Hemorrhoids (piles): symptomatic engorgement of the normal anal cushions. Covers Goligher grading I–IV, prevalence (17–31%), fiber evidence, banding versus surgery, 2024 ASCRS guideline shift, and embolization.

Hemorrhoidectomy

Hemorrhoidectomy is the surgical excision of hemorrhoidal tissue, considered the gold standard for grade III–IV hemorrhoids; its main variants are the closed Ferguson technique and the open Milligan–Morgan operation.

Hemosiderin

Hemosiderin (Hämosiderin) is the water-insoluble, iron-rich degradation product of ferritin and a long-term iron storage form; detected by Perls' Prussian blue stain and seen as hemosiderin-laden macrophages after hemorrhage.

Hemosiderosis

Hemosiderosis: intracellular accumulation of hemosiderin, degraded ferritin iron, in reticuloendothelial cells from transfusion, hemolysis, or iron-loading anemia; distinguished from genetic hemochromatosis and treated with chelation.

HEMOSTA-PN trial

HEMOSTA-PN (NCT07232927) is a randomized single-center trial at Ankara University testing FloSeal and Surgicel versus suturing alone in 150 patients undergoing partial nephrectomy for T1a-T1b renal tumors, 2023-2024.

Hemostasis

Hemostasis, the arrest of bleeding from injured vessels, involves vascular constriction, platelet plug formation, and coagulation; explained by the classic cascade and the modern cell-based model of Hoffman and Monroe.

Hemostat

Hemostat (hemostatic forceps, artery forceps): a ratcheted locking surgical clamp with ring handles used to compress blood vessels and stop bleeding; types include Crile, Kelly, Halsted mosquito, and Kocher; developed from Péan's and Spencer Wells' artery forceps.

Hemostatic Techniques

Hemostatic techniques are methods for controlling bleeding: pressure, ligation, clips, cautery, topical hemostatic agents, embolization, endoscopic and surgical hemostasis, and anticoagulation reversal (MeSH D006489).

Hemothorax

Hemothorax: blood accumulating in the pleural space, usually from blunt or penetrating chest trauma. Diagnosed by chest radiograph, E-FAST, or CT; treated with tube thoracostomy, VATS for retained blood, or thoracotomy when bleeding exceeds 1500 mL.

Hemp

Hemp is low-THC Cannabis sativa L. (under 0.3 percent delta-9 THC in US law) grown for fiber, seed, and CBD. Key facts: ancient European cultivation from 4280 BCE, yields up to 25 t/ha dry matter, 2025 US value $739 million, lower environmental impacts than cotton.

Hemp oil

Hemp oil (hemp seed oil) is the culinary oil pressed from Cannabis sativa seeds, naturally free of THC and CBD, GRAS-recognized by FDA in 2018, and distinct from hemp-derived CBD oil extracted from flowers and leaves.

Hemp seed protein

Hemp seed protein, protein from Cannabis sativa seeds sold as meal, concentrates (50-75%), and isolates (>85% protein); GRAS in the US via FDA GRN 771 (2018), complete protein high in arginine.

Henagliflozin proline

Henagliflozin proline (脯氨酸恒格列净, brand name Ruiqin) is an oral SGLT2 inhibitor by Jiangsu Hengrui Pharmaceuticals, approved in China in 2021 and described as the first SGLT2 inhibitor developed independently there.

Hendra virus

Hendra virus (HeV), originally equine morbillivirus, is a bat-borne henipavirus of Australia first identified in 1994 in Brisbane; Pteropus flying foxes are the reservoir, horses the amplifying host, with 7 human cases and 4 deaths.

Hendra virus infection

Hendra virus infection, caused by Hendra virus (HeV, equine morbillivirus), a bat-borne henipavirus in Australia; flying-fox reservoir, horse amplifying host, 7 human cases with 4 deaths, horse vaccine Equivac HeV, no human vaccine.

Hendrik G. Stunnenberg

Hendrik G. Stunnenberg is a Dutch molecular biologist known for epigenomics and trained immunity, professor at Radboud University from 1996 to 2019, now at the Prinses Máxima Centrum.

Hendrik Heinz

Hendrik Heinz is a professor of chemical and biological engineering at the University of Colorado Boulder, known for developing the INTERFACE force field for molecular simulation.

Hendrik N. Poinar

Hendrik N. Poinar is a molecular evolutionary geneticist at McMaster University who founded the McMaster Ancient DNA Centre and studies ancient DNA, including plague pathogens.

Hendrik Zwaardemaker

Hendrik Zwaardemaker was a Dutch physiologist, professor at Utrecht University from 1897 to 1927, who founded experimental research on smell and invented the first olfactometer in 1888.

Heng Li

Heng Li (李恒) is a bioinformatician and associate professor at Harvard Medical School and Dana-Farber, known for the BWA aligner, SAM format, minimap2, and hifiasm.

Heng Zhu

Heng Zhu is a molecular biology professor at Johns Hopkins School of Medicine, known for co-inventing functional protein microarrays that test thousands of proteins at once.

Hengrui Pharma (恒瑞医药)

Hengrui Pharma (恒瑞医药), formally Jiangsu Hengrui Pharmaceuticals, is a Chinese pharmaceutical company founded in 1970 and headquartered in Lianyungang, Jiangsu, focused on oncology and listed in Shanghai and Hong Kong.

Henipavirus

Henipavirus is a Paramyxoviridae genus of bat-borne RNA viruses including Nipah and Hendra viruses, which use ephrin-B2/B3 receptors, cause encephalitic disease with 57-80% case fatality, and lack approved human vaccines.

Henipavirus encephalitis

Henipavirus encephalitis is brain inflammation caused by Nipah or Hendra virus (genus Henipavirus, Paramyxoviridae), bat-borne zoonoses with 40–75% case fatality, relapsing encephalitis, no licensed treatment, and vaccine candidates in trials.