6 articles
Alkene difunctionalization
Alkene difunctionalization is the installation of two functional groups, identical or different, across a carbon–carbon double bond in a single operation, often via nickel, copper, or photoredox catalysis.
Aminotrifluoromethylation
Aminotrifluoromethylation is an alkene difunctionalization reaction that adds a trifluoromethyl group and a nitrogen group across the double bond, producing CF3-substituted lactams, aziridines, and pyrrolidines useful in medicinal chemistry.
Boracarboxylation
Boracarboxylation is a chemical reaction that adds a boryl group and a carboxylate across an alkene or alkyne with carbon dioxide and a diboron reagent.
Carboazidation
Carboazidation is a chemical transformation that installs a carbon-based group and an azido group across an alkene's double bond in a single step, forming both a C–C and a C–N bond.
Dicarbofunctionalization
Dicarbofunctionalization is a chemical transformation that adds two carbon-based groups across an alkene in a single operation, forging two carbon–carbon bonds, often with nickel catalysis.
Photochemical carboazidation
Photochemical carboazidation is a light-driven alkene difunctionalization reaction that installs a carbon group and an azido group across a carbon–carbon double bond, typically combining alkene, radical precursor, and azide source.