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Apologetics
Apologetics, also called fundamental theology, is the reasoned defense of a religious faith, best known in Christianity, where it provides rational warrant for Christian truth claims.
Apologia
An apologia is a formal, reasoned defense of a person, belief, or practice against accusation, a sense carried from the Greek courtroom into religious apologetics, and never meaning regret.
Apologies (The Bear)
Apologies is the ninth episode of season 3 of The Bear (2024), directed by Christopher Storer, written by Alex Russell, in which Carmy considers apologizing while the staff awaits the Chicago Tribune review; it ranks among the series' lowest-rated episodes.
Apology (Plato)
Plato's Apology of Socrates (Apologia Socratis), his only non-dialogue work, presents Socrates's defense speech (apologia) at his 399 BCE Athenian trial for impiety and corrupting the youth, ending in conviction, a death penalty, and arguments that death may be a blessing.
Apology of Hattusili III
The Apology of Hattusili III (CTH 81) is a Hittite text in which King Hattusili III justifies his seizure of the throne from his nephew Urhi-Teshub.
Apology Resolution
The Apology Resolution, Public Law 103-150 (S.J. Res. 19), is a 1993 US joint resolution signed by Clinton apologizing to Native Hawaiians for the 1893 overthrow of the Kingdom of Hawaii, with a disclaimer against claim settlements.
Apolonia
FK Apolonia (KF Apolonia Fier) is an Albanian football club founded in Fier on 17 June 1925 and named for the ancient city of Apollonia. Winner of the 1998 Albanian Cup, it now plays in the third-tier Kategoria e Dytë.
Apolônio Sales hydroelectric plant
The Apolônio Sales hydroelectric plant (Usina Hidrelétrica Apolônio Sales), formerly Moxotó, is a 400 MW hydroelectric plant on the São Francisco River in Alagoas, Brazil, opened in 1977.
APOM
APOM (apolipoprotein M, apoM; synonyms G3a, NG20) is a lipocalin apolipoprotein gene on 6p21.33, discovered in 1999, mainly HDL-bound, and the key HDL carrier of sphingosine-1-phosphate regulating endothelial barrier function.
Apomixis
Apomixis is asexual seed formation in plants, bypassing meiosis and fertilization to yield maternal clones; includes apomeiosis, parthenogenesis, gametophytic and sporophytic types, absent from major crops, engineered synthetically in rice.
Apomorphine
Apomorphine: non-ergoline dopamine agonist derived from morphine (Arppe 1845; Matthiessen and Wright 1869), no opioid activity; used as subcutaneous injection or infusion for Parkinson's disease off episodes; FDA approvals 2004, 2020, 2025.
Aponermin
Aponermin (埃普奈明, Shaite/沙艾特) is a recombinant circularly permuted TRAIL, the first approved DR4/DR5 agonist, approved in China in November 2023 with thalidomide and dexamethasone for relapsed/refractory multiple myeloma.
Apongo
Apongo, also known as Wager, was a West African prince enslaved in Jamaica who became a principal leader of the 1760 Westmoreland uprising, part of Tacky's Revolt.
Aponte family
The Aponte family founded and owns MSC, the Geneva-based shipping group started by Gianluigi and Rafaela Aponte in 1970, now the world's largest container line.
Aponus
Aponus (Aponi fons) was the Venetic god of the Euganean hot springs near Padua, later identified with Apollo; his name survives in Abano Terme, and his sacred spring, the fons Aponi, drew healing pilgrims and Tiberius's golden dice.
Apoo festival
The Apoo festival, also written Apoɔ, is an annual festival of the Bono people of Techiman, Ghana, held each March or April since around the 15th century.
Apoorva Raagangal (அபூர்வ ராகங்கள்)
Apoorva Raagangal (அபூர்வ ராகங்கள்), 1975 Tamil romantic drama by K. Balachander; Kamal Haasan, Srividya, Rajinikanth's debut; M.S. Viswanathan music; National Film Award-winning film about intergenerational relationships.
Apoorva Sagodharargal (அபூர்வ சகோதரர்கள்) (1989 film)
Apoorva Sagodharargal (அபூர்வ சகோதரர்கள்) is a 1989 Indian Tamil-language masala film directed by Singeetam Srinivasa Rao, with Kamal Haasan playing three roles, including a dwarf.
APOP/Kinyras Peyias FC
APOP/Kinyras Peyias FC, Cypriot club in Peyia, Paphos, formed 2003 by merger of APOP Peyias and Kinyras Empas; 2009 Cypriot Cup winners, first Paphos team in UEFA competition, disbanded after bankruptcy.
Apophasis
Apophasis, also called paralipsis or praeteritio, is a rhetorical figure in which a speaker denies intending to mention a subject while naming it, first defined around 90 BC.
Apophatic theology
Apophatic theology, also called negative theology or via negativa, approaches God through negation, saying what God is not. Rooted in biblical, Platonic, and Pseudo-Dionysian sources, it spans Christian, Jewish, and Islamic traditions and contrasts with cataphatic theology.
Apophenia
Apophenia (German Apophänie), coined by Klaus Conrad in 1958, is the tendency to perceive meaningful patterns in random data; originally a stage of delusion formation in early schizophrenia, now a general false-positive bias.
Apoplexy
Apoplexy (Greek apoplexia, "to strike down") was the historical term for sudden collapse with loss of consciousness, now called stroke. Used since Hippocrates, split into hemorrhagic and ischemic subtypes by Wepfer and Virchow, and abandoned from medical classifications in 1938.
Apoptosis
Apoptosis, or programmed cell death, named by Kerr, Wyllie, and Currie in 1972, is caspase-mediated, energy-dependent cell death via intrinsic, extrinsic, and perforin/granzyme pathways, without inflammation, distinct from necrosis.
Apoptosis inducing factor BLCAP
Apoptosis inducing factor BLCAP (BC10, bladder cancer-associated protein) is a human 20q11.23 gene encoding an 87-amino-acid, 10 kDa apoptosis-stimulating protein, imprinted in brain, A-to-I edited, and downregulated in several cancers.
Apoptosis-antagonizing transcription factor, C-terminal
AATF C-terminal domain (AATF_C, IPR012617, residues 418-502; AATF/Che-1/Traube superfamily domain) of the 560 aa AATF/Che-1 protein; carries NoLS, mediates nucleolar localization, c-Jun cofactor activity, and NGDN binding.
Apoptosome
Apoptosome: heptameric cytosolic complex of Apaf-1, cytochrome c, and dATP that activates caspase-9 in intrinsic apoptosis; orthologs CED-4 (C. elegans) and Dark (Drosophila); 3.8 Å cryo-EM structure; inactivation linked to cancer chemoresistance.
Apoptotic chromatin condensation inducer in the nucleus
Apoptotic chromatin condensation inducer in the nucleus, or Acinus (gene ACIN1), is a nuclear protein in animals and plants with roles in apoptosis and RNA splicing.
Apoptotic DNA fragmentation
Apoptotic DNA fragmentation: caspase-activated DNase (CAD/DFF40), released from ICAD by caspase-3, cuts chromatin into 50-300 kb then ~180 bp nucleosomal ladders, a hallmark of apoptosis.
Apoptotic protease-activating factor 1
Apaf-1 (APAF1, apoptotic protease-activating factor 1), a CED-4 homologue, is the cytosolic adaptor that with cytochrome c and dATP forms the heptameric apoptosome activating caspase-9 in intrinsic apoptosis.