519,064 articles
Aprinocarsen
Aprinocarsen (ISIS 3521, LY900003, Affinitak) is a 20-base phosphorothioate antisense oligonucleotide targeting PKC-alpha mRNA via RNase H1; trialed in gliomas, NSCLC, and other cancers without clinical benefit, then discontinued.
Apriori algorithm
The Apriori algorithm is a data mining algorithm for finding frequent itemsets and association rules in transaction databases, proposed by Rakes Agrawal and Ramakrishnan Srikant in 1994.
Apriyani Rahayu
Apriyani Rahayu, Indonesian badminton player born 1998 in Konawe, Sulawesi Tenggara; Tokyo 2020 women's doubles Olympic gold with Greysia Polii, Paris 2024 with Siti Fadia, and since June 2026 mixed doubles with Dejan Ferdinansyah.
Aprobarbital
Aprobarbital (Alurate, allylpropymal) is an intermediate-acting barbiturate sedative-hypnotic synthesized in the 1920s by Ernst Preiswerk, formerly used for short-term insomnia treatment, ATC N05CA05, now rarely prescribed and no longer commercially available in the US.
Aprocitentan
Aprocitentan (ACT-132577; Tryvio, Jeraygo) is an oral dual ETA/ETB endothelin receptor antagonist, active metabolite of macitentan, approved 2024 for resistant hypertension; PRECISION trial showed -3.8 mm Hg office systolic BP benefit versus placebo, main side effect edema.
Aprogen
Aprogen (에이프로젠) is a South Korean biopharmaceutical company founded in April 2000 that develops antibody biosimilars and novel antibody drugs, and was named Korea's first biopharmaceutical unicorn in January 2020.
Apron
Apron: a front-of-body protective garment, first recorded in English as "napron" in the early 14th century. Worn as workwear, servant's badge, 18th-century fashion accessory, mid-20th-century homemaker symbol, and modern PPE including lead X-ray aprons.
Apron feeder
An apron feeder, also called a pan feeder, is a heavy-duty feeder that extracts bulk material from stockpiles or hoppers at a controlled rate, typically feeding a primary crusher.
Aprostocetus
Aprostocetus Westwood, 1833 is a large genus of eulophid parasitoid wasps (Tetrastichinae) with 816 described species, parasitizing gall insects and cockroach oothecae, and used in biological control of gall wasps.
Aprotinin
Aprotinin (Trasylol, bovine pancreatic trypsin inhibitor) is a 58-amino-acid serine protease inhibitor used in cardiac surgery to cut bleeding and transfusion; suspended in 2007–2008 after the BART trial, partially reinstated in 2012.
Aprustum
Aprustum (Aprusto, Greek Abystron) was an ancient inland town of Bruttium in modern Calabria, Italy, known only from Pliny (Aprustani) and Ptolemy; its site remains unidentified, with proposed locations including Castrovillari, Argusto, and Santa Severina.
APS kinase
APS kinase (adenylylsulfate kinase, EC 2.7.1.25) phosphorylates adenosine 5'-phosphosulfate to PAPS, the sulfate donor for sulfotransferases; found standalone in bacteria, fused in PAPS synthases, redox-regulated in plants.
APS March Meeting
The APS March Meeting is the American Physical Society's annual conference, the world's largest physics meeting, known for landmark announcements like the 1987 high-temperature superconductivity results.
APS-C
APS-C, or Advanced Photo System type-C, is a digital camera image sensor format of roughly 23.5 × 15.6 mm, named after the 1996 APS film's Classic frame.
APSALS study
APSALS (Australian Parental Supply of Alcohol Longitudinal Study), a 2010 UNSW NDARC prospective cohort of 1,927 parent-child dyads followed annually, finding parental alcohol supply increases adolescent binge drinking, harms, and alcohol use disorder risk.
Apsara (अप्सरस्)
Apsara (अप्सरस्, Prakrit accharā): celestial nymphs of Hindu, Buddhist, and Jain mythology, dancers of Indra's heaven and wives of the Gandharvas; named in the Amarakosha (Urvashi, Rambha, Menaka) and depicted across Asian art.
Apse
An apse is a semicircular or polygonal recess at the end of a building, most often a church's east end, typically housing the altar under a half-dome.
Apsidal precession
Apsidal precession, also called perihelion precession or apsidal motion, is the gradual rotation of an orbit's line of apsides; Mercury's unexplained 43-arcsecond-per-century advance was explained by general relativity.
Apsis
An apsis is either extreme point of an elliptical orbit, the periapsis (closest approach) or apoapsis (farthest); around the Sun these are called perihelion and aphelion.
Apsley Cherry-Garrard
Apsley George Benet Cherry-Garrard (1886–1959), English polar explorer and writer; assistant zoologist on Scott's Terra Nova expedition, survivor of the 35-day Cape Crozier winter journey, member of the 1912 search party, and author of The Worst Journey in the World (1922).
Apsley House
Apsley House, known as "No. 1 London," is a town house at Hyde Park Corner built by Robert Adam in 1771–1778 and home to the Duke of Wellington.
Apsley Marshes
Apsley Marshes: 880-hectare Tasmanian Ramsar wetland (site 255, listed 1982) at the Apsley River mouth, adjacent to Moulting Lagoon; important for black swan nesting, threatened bittern, grayling, and swamp everlasting.
Apsu Sulci
Apsu Sulci is a 1,950 km grooved-terrain system (sulcus) on Jupiter's moon Ganymede, centered at 37.5° S, 225.2° W; IAU-named in 1979 after the Sumero-Akkadian primordial ocean and mapped as quadrangle Jg-13.
Apsus Vallis
Apsus Vallis is an IAU-approved valley (vallis) on Mars near the Elysium volcanic complex, about 120 km across, centered near 34.8N 135E, named in 1985 for a classical river of ancient Macedonia, present-day Greece.
APsystems
APsystems (昱能科技) is a Chinese manufacturer of microinverters and module-level power electronics for solar, founded in 2010 in Jiaxing, Zhejiang, and listed on the Shanghai STAR Market.
APT (package manager)
APT (Advanced Package Tool) is the main command-line package manager for Debian and derivatives such as Ubuntu, installing and upgrading packages from authenticated repositories while resolving dependencies.
APT Medical (惠泰医疗)
APT Medical Inc. (惠泰医疗) is a Shenzhen medical device company founded in 2002 that makes cardiac electrophysiology and cardiovascular interventional devices; Mindray has controlled it since 2024.
Apt Pupil
Apt Pupil is a 1982 Stephen King novella from Different Seasons ('Summer of Corruption') in which 13-year-old Todd Bowden blackmails Nazi war criminal Kurt Dussander into recounting the Holocaust, with fatal results for both; adapted by Bryan Singer in 1998.
Apt Pupil (film)
Apt Pupil (1998) is Bryan Singer's psychological drama, adapted by Brandon Boyce from Stephen King's novella in Different Seasons, starring Brad Renfro as teen Todd Bowden and Ian McKellen as hiding Nazi Kurt Dussander; released October 23, 1998, grossed $8.8 million.
APT Satellite Holdings
APT Satellite Holdings is a Hong Kong-listed satellite operator, established in 1992, whose APSTAR fleet serves broadcasters and telecom customers across Asia, Europe, Africa, and Oceania.