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Aspartate decarboxylase

Aspartate decarboxylase (PanD, ADC, EC 4.1.1.11) is the bacterial pyruvoyl-dependent enzyme converting L-aspartate to β-alanine, the committed step of pantothenate and coenzyme A biosynthesis.

Aspartate kinase

Aspartate kinase (aspartokinase, AK, EC 2.7.2.4) is the first committed, allosterically feedback-inhibited enzyme of aspartate-family amino acid biosynthesis (lysine, threonine, methionine, isoleucine) in microbes and plants, absent from animals.

Aspartate transaminase

Aspartate transaminase (AST, GOT), a PLP-dependent enzyme interconverting aspartate and alpha-ketoglutarate with oxaloacetate and glutamate; cytosolic and mitochondrial isoenzymes, malate-aspartate shuttle role, and standard serum liver-injury marker.

Aspartate-semialdehyde dehydrogenase

Aspartate-semialdehyde dehydrogenase (ASADH, EC 1.2.1.11, asd gene) is a dimeric NADPH-dependent enzyme converting aspartyl phosphate to aspartate-semialdehyde at the branch point of bacterial, plant, and fungal lysine and threonine/methionine biosynthesis.

Aspartic acid

Aspartic acid, also known as L-aspartate, is a non-essential acidic amino acid encoded by codons GAT and GAC, used in proteins, nucleotide synthesis, and the urea cycle.

Aspartoacylase

Aspartoacylase (ASPA, ACY2) is a zinc carboxypeptidase enzyme that hydrolyzes N-acetylaspartate to aspartate and acetate; ASPA gene mutations cause Canavan disease, a leukodystrophy targeted by AAV gene therapy.

Aspartylglucosaminidase

Aspartylglucosaminidase (AGA, glycosylasparaginase, EC 3.5.1.26) is a lysosomal Ntn-hydrolase on chromosome 4q34.3 that cleaves GlcNAc-Asn bonds; its deficiency causes aspartylglucosaminuria, common in Finland via the C163S founder mutation.

Aspartylglucosaminuria

Aspartylglucosaminuria (AGU, aspartylglucosaminidase deficiency) is a rare autosomal recessive lysosomal storage disorder from biallelic AGA variants on 4q34.3, enriched in Finland, causing developmental delay, neurodegeneration, and premature death; AAV9 gene therapy is in trials.

Asparuh of Bulgaria

Asparuh (Аспарух) was khan of the Bulgars, reigning from 679 to 701, who founded the First Bulgarian state, which Byzantium recognized by treaty in 681.

Aspasia (σπασία)

Aspasia (σπασία) of Miletus, fifth-century BC metic and companion of Pericles in Athens, remembered as teacher of Socrates and Pericles in rhetoric; her biography rests on comedy, Socratic dialogue, and Plutarch.

Aspasia Corona

Aspasia Corona is a corona, a quasi-circular volcano-tectonic feature, on the surface of Venus, 200 km across in the V-05 quadrangle and named for Aspasia of ancient Greece.

Aspasia Manos

Aspasia Manos (Ασπασία Μάνου, 1896–1972), Greek aristocrat from a Phanariote family who secretly married King Alexander I of Greece in 1919; styled Princess Aspasia of Greece and Denmark in 1922, distinct from Aspasia of Miletus.

Aspazija

Aspazija was the pen name of Johanna Rozenberga (1865–1943), a Latvian poet, playwright, and publicist who founded modern Latvian poetry and drama, and the wife of Rainis.

AsPC-1

AsPC-1 (CVCL_0152, ATCC CRL-1682) is a human pancreatic ductal adenocarcinoma cell line established in 1982 from the ascites of a 62-year-old woman, carrying homozygous KRAS G12D, SMAD4 R100T, and CDKN2A frameshift mutations, used in drug screening and metastasis research.

Aspect Biosystems

Aspect Biosystems is a Vancouver biotechnology company founded in 2013 as a UBC spinout that develops bioprinted tissue therapeutics, led by an islet replacement therapy for type 1 diabetes.

Aspect Capital

Aspect Capital is a London-based systematic hedge fund manager founded in 1997 by Anthony Todd and Martin Lueck, managing over $9 billion in trend-following managed futures strategies.

Aspect ratio

An aspect ratio is the ratio of width to height of an image, written as 16:9 or 1.78:1, common ratios running from 1.375:1 to 2.76:1 in film.

Aspect ratio (aeronautics)

In aeronautics, the aspect ratio of a wing is its span squared divided by wing area, a measure of how long and slender the wing is.

Aspect ratio (image)

Aspect ratio (image), also called picture or display aspect ratio, is the width-to-height ratio of a film frame or screen, from Academy 1.37:1 and 1.85:1 theatrical widescreen to 16:9 HDTV and vertical 9:16 video.

Aspect-based sentiment analysis

Aspect-based sentiment analysis (ABSA) is a natural language processing method that identifies sentiment toward specific aspects of an entity, such as a laptop's screen or keyboard, in text.

Aspect-oriented programming

Aspect-oriented programming, also called aspect-oriented software development, is a programming paradigm coined in 1997 at Xerox PARC that improves modularity by isolating crosscutting concerns like logging, security, and transaction management.

Aspect's experiment

Aspect's experiment is a 1982 Bell test in which Alain Aspect, Jean Dalibard, and Gérard Roger switched polarization analyzers while photons were in flight, violating Bell's inequalities.

Aspelta

Aspelta was a king of Kush around 593 BC who succeeded his brother Anlamani, recorded his divine election on the Election Stela, and was buried in a pyramid at Nuri.

Aspen

Aspen, chiefly quaking aspen (Populus tremuloides), is North America's most widely distributed tree, a clonal species regenerating by root suckering and seed, valued for biodiversity and acting as a natural wildfire firebreak.

Aspen Aerogels

Aspen Aerogels, founded in 2001 in Northborough, Massachusetts, is an American company making aerogel insulation for refineries, buildings, and subsea pipelines, plus thermal barriers for electric vehicle batteries.

Aspen Institute

Aspen Institute, also Aspen Institute for Humanistic Studies, is a global nonprofit leadership and convening organization founded by Walter Paepcke in Aspen, Colorado, after the 1949 Goethe Bicentennial; known for its Executive Seminar, Aspen Ideas Festival, Aspen Security Forum, and Henry Crown Fellowship.

Aspen Ladd

Aspen Ladd (born 1995) is an American MMA fighter from Folsom, California, 12-5 professionally, who fought in Invicta FC, the UFC (4-3), PFL, and Bellator, known for grappling and ground-and-pound.

Aspen Music Festival and School

Aspen Music Festival and School (AMFS), founded 1949 by the Paepckes in Aspen, Colorado, is a classical summer festival and training school: eight-week season, 450+ students, Robert Spano music director, Meghan Umber next CEO.

Aspen Plus

Aspen Plus is a commercial process simulator sold by Aspen Technology that chemical engineers use to model, design, and optimize chemical processes, typically in steady state.

Aspen, Colorado

Aspen, Colorado, is a resort city in Pitkin County's Roaring Fork Valley, founded as a silver-mining camp in 1879 and now known for its four ski mountains.