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Tolazoline
Tolazoline, marketed as Priscoline and Tolazine, is a synthetic alpha-adrenoceptor antagonist and vasodilator once used in newborns and now used to reverse xylazine in horses.
Tolbachik
Tolbachik (Tolbachik volcanic massif) is a basaltic volcano at the southern end of the Klyuchevskoy group, Kamchatka, Russia, made of Ostry and Plosky Tolbachik stratovolcanoes and the Tolbachinsky Dol cone field; site of the 1975–76 Great Tolbachik Fissure Eruption and the 2012–13 fissure eruption.
Tolbutamide
Tolbutamide, sold as Orinase, is a first-generation sulfonylurea drug introduced in 1956 that lowers blood glucose in type 2 diabetes and serves as a probe for CYP2C9.
Tolcapone
Tolcapone (Tasmar) is a first-generation oral COMT inhibitor used with levodopa/carbidopa for Parkinson's motor fluctuations; most effective in its class but second-line due to rare fatal hepatotoxicity requiring liver monitoring.
Tolclofos methyl
Tolclofos-methyl (Rizolex) is an organophosphorus contact fungicide, CAS 57018-04-9, used mainly as a potato seed treatment against Rhizoctonia solani; EU-approved for potatoes and ornamentals until 2034.
Toldi (tank)
The 38M Toldi was a Hungarian light tank developed from the Swedish Landsverk L-60, produced from 1940 to 1942 and forming the backbone of Hungary's armored forces in 1940 and 1941.
Toldi estéje
Toldi estéje ("Toldi's Evening") is a Hungarian narrative poem in six cantos by János Arany, the second part of his Toldi trilogy, published in 1854.
Tole Bi
Tole Bi Alibekuly (Төле би Әлібекұлы, 1663–1756) was a Kazakh judge-statesman and orator, chief biy of the Senior Juz and co-compiler of the Zhety Zhargy steppe law code.
Tolebrutinib
Tolebrutinib (Cenrifki, PRN2246, SAR442168) is Sanofi's oral brain-penetrant covalent BTK inhibitor for multiple sclerosis; it slowed disability progression in non-relapsing SPMS (HERCULES) but was rejected by the FDA over liver injury, while gaining EU approval in 2026.
Toledo
Toledo (ATCC CRL-2631, CVCL_3611) is a human B lymphocyte cell line established in 1990 from peripheral blood of an adult female with diffuse large B-cell lymphoma, GCB type, EBV-negative, KRAS G13D, CREBBP/EP300 double mutant.
Toledo Bend Reservoir
Toledo Bend Reservoir is an impoundment of the Sabine River on the Texas–Louisiana border, formed by a dam completed in 1969 and used for water supply, hydroelectric power, and recreation.
Toledo Cathedral
Toledo Cathedral, formally the Cathedral of Saint Mary of Toledo, is Spain's Primate Gothic cathedral in Toledo, begun in 1226 under Ferdinand III and completed in 1493.
Toledo Edison
The Toledo Edison Company is an investor-owned electric distribution utility headquartered in Toledo, Ohio, serving ten northwest Ohio counties and regulated by the Public Utilities Commission of Ohio as a subsidiary of FirstEnergy Corp.
Toledo Montes
Toledo Montes, a named mountain range on Saturn's moon Iapetus, part of the 20-km-tall equatorial ridge; its flat-topped peaks are modified by landslides, named in the Charlemagne/Roland nomenclature theme.
Toledo Mud Hens
Toledo Mud Hens, Triple-A International League affiliate of the Detroit Tigers since 1987, playing at Fifth Third Field in Toledo, Ohio; named in 1896 for American coots near Bay View Park.
Toledo refinery (Cenovus)
The Toledo refinery is an oil refinery in Oregon, Ohio, near Toledo, opened in 1919 and owned by Cenovus Energy since 2023, with a capacity of 160,000 barrels per day.
Toledo reforms in Peru
The Toledo reforms in Peru (Virreinato de Francisco de Toledo) were Viceroy Francisco de Toledo's 1569–1581 reorganization of the Viceroyalty of Peru, built on resettlement and Potosí mine labor.
Toledo steel
Toledo steel is the famed sword steel of Toledo, Spain, whose blades were considered Europe's best between the 15th and 17th centuries for temper and flexibility.
Toledo War
The Toledo War (1835–1836), also called the Michigan–Ohio War, was an almost bloodless boundary dispute over the 468-square-mile Toledo Strip; Ohio kept Toledo, Michigan received the western Upper Peninsula and statehood in 1837.
Toledo, Central Visayas
Toledo (Lungsod ng Toledo) is a coastal component city in Cebu, Central Visayas, Philippines; chartered 1960, formerly Hinulawan/Jinulauan, known as the Copper City for the Atlas/Carmen Copper mine and the ferry link to San Carlos, Negros.
Toledo, Ohio
Toledo, Ohio (the Glass City) is Ohio's fourth largest city, a Lake Erie port on the Maumee River with about 263,000 residents, a glass and automotive manufacturing history, and a 300,000-resident goal for 2045.
Toledo, Spain
Toledo, Spain: historic Castilla-La Mancha capital 70 km south of Madrid, UNESCO World Heritage Site since 1986, the "city of the three cultures" on the Tagus, a major cultural tourism destination facing depopulation and planning pressures.
Toledo's visita and reducciones of Peru
Toledo's visita and reducciones of Peru (reducciones de indios del virrey Toledo) was Viceroy Francisco de Toledo's 1570s program concentrating dispersed Andeans into planned towns called reducciones.
Tolentinum
Tolentinum, ancient Roman municipium in Picenum (Regio V) on the left bank of the Chienti, site of modern Tolentino, Marche; Velina tribe, ager Tolentinus, attested by Pliny and the Liber Coloniarum.
Tolerability study
A tolerability study is a clinical study assessing how well participants can tolerate a drug or treatment, monitoring adverse effects, discontinuations, and patients' own experience of side effects.
Tolerance analysis
Tolerance analysis is the engineering method for quantifying how dimensional variations in manufactured parts accumulate and propagate through an assembly, affecting fit, function, and assembly of the final product.
Tolerance design
Tolerance design is the engineering method of allocating dimensional and parameter tolerances to components and processes so assemblies meet functional and quality requirements at acceptable manufacturing cost.
Tolfenpyrad
Tolfenpyrad (OMI 88; trade names HACHI-HACHI, APTA, TORAC, BEXAR) is a pyrazoleamide METI insecticide-acaricide, IRAC group 21A mitochondrial complex I inhibitor, registered in Japan in 2002 and the US in 2010, never approved in the EU.
Tolgau
Tolgau (Kazakh: толғау) is a genre of reflective, aphoristic oral poetry practiced by the zhyrau, poet-bards of the Kazakh, Karakalpak, and Nogai peoples, flourishing from the 15th to 19th centuries.
Tolghau
Tolghau (Kazakh: толғау, meaning reflection) is a genre of oral poetic reflection among the Kazakh, Karakalpak, and Nogai peoples, and the principal genre of the zhyrau poet-sages.