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TPMT
TPMT (thiopurine S-methyltransferase), gene on chromosome 6, encodes the enzyme that S-methylates and inactivates thiopurine drugs; deficiency (about 1 in 300, mainly TPMT*2/3 alleles) causes myelosuppression risk and drives phenotype/genotype testing and CPIC, DPWG dosing guidelines.
TPP1
TPP1 (tripeptidyl peptidase 1, formerly CLN2) is a human chromosome 11 gene encoding a lysosomal serine protease that cleaves N-terminal tripeptides; mutations cause CLN2 disease and SCAR7, treated with cerliponase alfa. Not the telomere protein ACD.
TpPa covalent organic framework
TpPa covalent organic framework is a stable two-dimensional COF made from triformylphloroglucinol and phenylenediamine, first synthesized in 2012 and used for CO2 capture and separations.
TPS report
A TPS report, or Testing Procedure Specification, is a software quality assurance document under IEEE 829 describing a test's setup, procedure, and expected outcomes, later made famous by the 1999 film Office Space.
TPT1
TPT1 (TCTP, fortilin, histamine-releasing factor) is a highly conserved eukaryotic protein-coding gene on human chromosome 13 encoding a 172-amino-acid anti-apoptotic, calcium- and tubulin-binding protein implicated in stress response, development, and cancer.
TPX2
TPX2 (Targeting Protein for Xklp2, also p100/REPP86/HCA519) is a microtubule-associated spindle assembly factor regulated by RanGTP/importin, an activator of Aurora A kinase, required for branching microtubule nucleation, and overexpressed as a prognostic biomarker in many cancers.
TPz Fuchs
The TPz Fuchs (M93 Fox) is a German six-wheeled amphibious armored transport vehicle built since 1979, serving with roughly 40 variants from NBC reconnaissance to electronic warfare.
Tq Ventures
Tq Ventures is a New York venture capital firm that self-reports approximately $2 billion in assets under management. It has raised over $455 million across its three funds.
TQC3721
TQC3721 (TQC-3721) is an inhaled dual PDE3/4 inhibitor by Chia Tai Tianqing for COPD; positive PACER-II phase 2 data, phase III underway, licensed to AstraZeneca in 2026.
TQH2722 (IL-4Rα antibody)
TQH2722 (BSI-045A) is a humanized IgG4 anti-IL-4Rα monoclonal antibody by Chia Tai Tianqing and Biotheus, blocking IL-4/IL-13 signaling; Phase III in atopic dermatitis with CDE NDA accepted in 2026.
TQL trial
TQL trial (NCT05349656), a completed Alexandria University randomized quadruple-masked trial comparing transmuscular quadratus lumborum block versus PENG block for postoperative analgesia in 40 children aged 1 to 6 undergoing open hip surgery for developmental dysplasia of the hip.
TR-069
TR-069, also known as the CPE WAN Management Protocol (CWMP), is a Broadband Forum specification for remotely managing routers and modems, first published in 2004.
TR-49
TR-49 is a 2026 narrative deduction puzzle game by inkle Ltd, released January 21, 2026 on PC and later Switch. Players search a WWII Bletchley Park computer's archive of lost books via four-character codes; Metacritic 82, Steam Very Positive.
TR-55 (hydrology)
TR-55, Technical Release 55, is a USDA publication presenting simplified procedures for estimating storm runoff volume, peak discharge, and storage volumes in small United States watersheds.
TR-85
The TR-85 (Tanc Românesc Model 1985) is a Romanian main battle tank based on the Soviet T-55; its modernized TR-85M1 Bizonul variant meets NATO standards.
Tr1X
Tr1X is a San Diego biotechnology company developing allogeneic, off-the-shelf Type 1 regulatory T cell therapies for autoimmune and inflammatory diseases, with lead candidate TRX103 in Phase 1/2a trials.
Tra Kieu pedestal
The Trà Kiệu pedestal (đài thờ Trà Kiệu) is a colossal carved sandstone pedestal-shrine from the ancient Cham site of Trà Kiệu in central Vietnam, now in the Da Nang Museum of Cham Sculpture.
Tra Kieu stele
The Tra Kieu stele refers to two 7th-century Sanskrit inscriptions on sandstone pedestals found at Tra Kieu, Vietnam, the ancient Champa capital Simhapura, issued by king Prakashadharman.
TraA
TraA names two bacterial proteins: the polymorphic myxobacterial cell-surface receptor governing kin recognition and outer membrane exchange, and a conjugation protein acting as relaxase or F-pilus pilin (InterPro IPR008873).
Trabant
The Trabant, also known as the Trabi, was a small East German car built in Zwickau from 1957 to 1991, with a two-stroke engine and Duroplast body.
Trabectedin
Trabectedin (ET-743, Yondelis) is a marine-derived alkylating anticancer drug from the tunicate Ecteinascidia turbinata, approved in the EU in 2007 for soft tissue sarcoma and relapsed platinum-sensitive ovarian cancer, and by the FDA in 2015.
Trabecular bone score
The trabecular bone score (TBS) is a software-derived index of bone texture computed from routine lumbar spine DXA scans, which complements bone density in assessing fracture risk.
Trabeculectomy
Trabeculectomy is a glaucoma operation that creates a small drainage channel in the eye to lower intraocular pressure, and is often described as the gold standard.
Trabeculoplasty
Trabeculoplasty is a laser procedure applied to the eye's trabecular meshwork drainage tissue to improve outflow and lower intraocular pressure in open-angle glaucoma, with variants including ALT, SLT, and MLT.
Trabeculotomy
Trabeculotomy is a glaucoma operation that restores fluid drainage by cutting the trabecular meshwork and opening Schlemm's canal, introduced by R. Smith in 1960 and used mainly for congenital glaucoma.
Trabedersen
Trabedersen (AP 12009, OT-101) is an 18-mer phosphorothioate antisense oligonucleotide silencing TGF-β2; trialed intratumorally in high-grade glioma and intravenously in pancreatic cancer, melanoma, and colorectal cancer.
Trabodenoson
Trabodenoson (INO-8875), a selective adenosine A1 receptor agonist eye drop developed by Inotek for glaucoma; lowered intraocular pressure in Phase 2 but failed its MATrX-1 Phase 3 and latanoprost combination trials, and development was discontinued in July 2017.
Trabzon
Trabzon (Trebizond), a Black Sea port city in northeastern Türkiye; founded as a Greek colony, capital of the Empire of Trebizond 1204–1461, Ottoman princely city, birthplace of Süleyman the Magnificent, population 823,323 (2025).
Trabzonspor
Trabzonspor (Trabzonspor Kulübü), the Black Sea Storm, is a Turkish football club founded 2 August 1967 by a four-club merger in Trabzon. Seven-time Süper Lig champion (first non-Istanbul winner, 1975-76; latest 2022), eight Turkish Cups, Borsa Istanbul-listed, signed Mohamed Salah in 2026.
Trace (linear algebra)
The trace of a square matrix, also called the matrix trace, is the sum of its main diagonal entries; it is basis-independent and equals the sum of the eigenvalues.