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Trifluoromethoxylation

Trifluoromethoxylation is the introduction of the trifluoromethoxy group (–OCF₃) into an organic molecule, producing trifluoromethyl ethers valued in pharmaceuticals, agrochemicals, and materials for their stability.

Trifluoromethylation

Trifluoromethylation is a chemical reaction that introduces a trifluoromethyl (CF3) group into organic molecules, replacing hydrogen or halogen; 15 of the top 200 drugs of 2018 contain the group.

Trifluoromethylation of arylboronic acids

Trifluoromethylation of arylboronic acids is a family of reactions converting Ar–B(OH)2 into trifluoromethylated arenes, typically with copper and a CF3 source, first reported in 2010 and 2011.

Trifluoromethylthio compounds

Trifluoromethylthio compounds are organic sulfides bearing the SCF3 group, whose strong lipophilicity and metabolic stability make it valuable in marketed drugs and the insecticide Fipronil.

Trifluoromethylthiolation

Trifluoromethylthiolation is a chemical reaction that installs the trifluoromethylthio group (SCF3) onto organic molecules, valued in drug discovery for combining strong electron withdrawal with high lipophilicity.

Trifluperidol

Trifluperidol (R-2498, Triperidol) is a butyrophenone antipsychotic and dopamine antagonist similar to haloperidol, synthesized 1959 by Janssen, used for psychoses including schizophrenia and mania; not FDA-approved, mainly available in India.

Triflupromazine

Triflupromazine (Vesprin, Siquil, fluopromazine) is a phenothiazine dopamine D1/D2 antagonist antipsychotic and antiemetic, FDA-approved 1957, discontinued for humans but still a veterinary tranquilizer for dogs, cats, and horses.

Trifluralin

Trifluralin, sold as Treflan, is a selective pre-emergence dinitroaniline herbicide used to control annual grasses and broadleaf weeds in agricultural crops, first registered in the United States in 1963.

Trifluridine

Trifluridine, also known as trifluorothymidine or TFT, is a fluorinated antiviral drug used as 1% eye drops for herpes simplex keratitis and in Lonsurf for colorectal cancer.

Triflusal

Triflusal, marketed as Disgren, is an oral antiplatelet drug related to the salicylates, used to prevent recurrent stroke and myocardial infarction in Europe and South Korea.

Triflusulfuron

Triflusulfuron (triflusulfuron-methyl, DPX-66037, UpBeet, Debut) is a triazinylsulfonylurea ALS-inhibiting herbicide for weeds in sugar beet; EU approval expired November 2023.

Trifoliate orange (枳)

Trifoliate orange (枳, karatachi), Citrus trifoliata, formerly Poncirus trifoliata, is a deciduous thorny Chinese citrus relative, the hardiest citrus, used worldwide as a cold-hardy, disease-tolerant semi-dwarfing rootstock and in citrus hybrid breeding.

Trifolitoxin

Trifolitoxin (TFX) is a peptide antibiotic produced by Rhizobium leguminosarum bv. trifolii strain T24, a clover-nodulating bacterium, which lets producing strains outcompete sensitive rhizobia for nodules.

Trifolium alexandrinum

Trifolium alexandrinum, known as berseem or Egyptian clover, is an annual forage legume grown as a winter feed crop in the Nile Valley and northern India.

Trifolium hybridum

Trifolium hybridum, alsike clover, is a short-lived perennial forage legume in Fabaceae, native from the Mediterranean to Iran, adapted to wet acidic soils, causing bloat and photosensitization, and not a red-white clover hybrid.

Trifolium incarnatum

Trifolium incarnatum (crimson clover), annual Fabaceae legume native to Europe to NW Iran, grown for forage, winter cover crop, and green manure; fixes 70–150 lb N/acre, red flower heads, IUCN least concern.

Trifolium pratense

Trifolium pratense (red clover, purple clover, rotklee) is a short-lived perennial forage legume in Fabaceae, native to Europe and western Asia, grown for high-protein feed and nitrogen fixation, second only to lucerne among sown forage legumes.

Trifolium repens

Trifolium repens, white or Dutch clover, is a stoloniferous perennial Fabaceae legume of Europe and the Mediterranean, grown worldwide for forage, nitrogen fixation, honey, and pollinator lawns.

Trifolium subterraneum

Trifolium subterraneum, subterranean clover or subclover, an annual Mediterranean pasture legume (Fabaceae) with three subspecies (subterraneum, yanninicum, brachycalycinum) that buries its seed pods underground, enabling self-regeneration in grazed pastures, notably in southern Australia.

Trifon Natsis

Trifon Natsis (Greek: Τρύφων Νάτσης, born 1959) is a Greek-born financier who co-founded the Brevan Howard hedge fund in 2002, traded there until 2025, and co-owns Orilina Properties.

Triforce

Triforce (トライフォース) is the divine golden triangle of Nintendo's Legend of Zelda series, left by goddesses Din, Nayru, and Farore; it grants wishes, splits into Power, Wisdom, and Courage pieces held by Ganondorf, Zelda, and Link.

TRIGA

TRIGA (Training, Research, Isotopes, General Atomics) is a class of nuclear research reactors made by General Atomics, first critical in 1958 and prized for inherent safety.

Trigano S.A.

Trigano S.A. is a French company headquartered in Vendée that designs and manufactures motorhomes, caravans, and mobile homes, and is one of Europe's largest motorhome producers.

Trigeminal nerve

Trigeminal nerve (CN V), the largest cranial nerve, a mixed sensory and motor nerve with ophthalmic (V1), maxillary (V2), and mandibular (V3) branches; V3 alone carries motor fibers to the muscles of mastication; best-known disorder is trigeminal neuralgia.

Trigeminal nerve stimulation

Trigeminal nerve stimulation (TNS) is a neuromodulation treatment that delivers electrical pulses to forehead branches of the trigeminal nerve to treat epilepsy, migraine, depression, and ADHD.

Trigeminal neuralgia

Trigeminal neuralgia: sudden severe electric-shock-like unilateral facial pain from trigeminal nerve compression, usually by the superior cerebellar artery; treated first with carbamazepine, then microvascular decompression, radiosurgery, or rhizotomy.

Trigeminal trophic syndrome

Trigeminal trophic syndrome (TTS), or trigeminal neurotrophic ulceration, is a rare self-induced facial ulceration, typically of the nasal ala, after trigeminal nerve injury from neuralgia treatment, stroke, or herpes zoster.

Trigeneration

Trigeneration, also known as combined cooling, heating and power (CCHP), is the simultaneous production of electricity, useful heat, and cooling from one fuel input, typically using an absorption chiller.

Trigga (jungle MC)

Trigga, real name Tundy Smith, is an English drum and bass and jungle MC from Moss Side, Manchester, known as a founder member of the Shadow Demon Coalition.

Trigger (firearms)

A trigger is the lever a shooter presses to release a firearm's firing mechanism, most commonly by freeing a sear holding a cocked hammer or striker.