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TRPM8
TRPM8 (CMR1, trp-p8) is the human cold- and menthol-gated, calcium-permeable TRP cation channel on chromosome 2q37.1; activated below 23-28 degrees Celsius, it is the target of the 2025 FDA-approved dry eye drug TRYPTYR and of pain and cancer drug programs.
TRPM8 Channel-Associated Factors
TRPM8 channel-associated factors (TCAFs; TCAF1, TCAF2, TCAF3) are proteins that bind the cold-sensing TRPM8 ion channel, control its trafficking, and oppositely regulate gating, with roles in prostate, pancreatic, and colorectal cancer.
TRPS1
TRPS1 (transcriptional repressor GATA binding 1) is a chromosome 8 gene encoding an atypical single-GATA-zinc-finger transcriptional repressor; mutations cause trichorhinophalangeal syndrome types I and III, and the protein serves as a breast cancer immunohistochemical marker.
TRPV1
TRPV1 (transient receptor potential vanilloid 1, formerly VR1 or capsaicin receptor) is a calcium-permeable sensory ion channel gated by capsaicin, noxious heat above 43 °C, and protons; cloned in 1997, it regulates pain and body temperature, and its antagonists cause hyperthermia.
TRPV6
TRPV6 (ECaC2, CaT1), a calcium-selective TRP vanilloid epithelial ion channel on chromosome 7q34, mediates vitamin D-regulated intestinal calcium absorption; dysregulation links to chronic pancreatitis and cancers, making it a drug target.
TRRAP
TRRAP (transformation/transcription domain-associated protein, PAF400) is a 434 kDa human pseudokinase at 7q22.1, a shared subunit of SAGA, NuA4/TIP60, and PCAF HAT complexes that recruits them to chromatin for transcription and DNA repair; pathogenic variants cause autosomal dominant neurodevelopmental disorder and hearing loss.
TRS Information Technology (拓尔思)
TRS Information Technology (拓尔思) is a Beijing-based software company founded in 1993, known for Chinese natural language processing, full-text search, and big-data platforms, listed on Shenzhen's ChiNext board since 2011.
TRS-80
The TRS-80, nicknamed the Trash-80, was a line of personal computers sold by Tandy's Radio Shack from 1977; the Model I sold over 100,000 units in its first year, half of 1978's personal computer sales.
TRS-80 Color Computer
The TRS-80 Color Computer, also known as the Tandy Color Computer or CoCo, is a line of 8-bit home computers sold by Radio Shack from 1980 to 1990.
TRS-80 Model 100
The TRS-80 Model 100 is a battery-powered portable computer introduced in 1983 by Radio Shack, licensed from Kyocera's Kyotronic 85 and widely used by journalists to file stories over its built-in modem.
TRSP domain
TRSP domain (Pfam PF12500, InterPro IPR022537), a ~138-residue bacterial protein domain found C-terminal to PRTase_2 domains in hypothetical proteins; distinct from the Plasmodium TRSP gene and mouse Trsp tRNA gene.
TRT World
TRT World: Turkey's first English-language international news channel, launched 2015, Istanbul-based, part of state broadcaster TRT (founded 1964); criticized as pro-AKP, foreign-agent registered in the US in 2019.
TRU
TRU, also credited as The Real Untouchables, was a New Orleans gangsta rap group formed by Master P with his brothers Silkk the Shocker and C-Murder, active until 2005.
Tru Arrow Technology Partners Civ
Tru Arrow Technology Partners, known publicly as Tru Arrow Partners, is a New York-based venture capital firm focused on technology companies, co-founded by Adam Silverschotz and Glenn Fuhrman in 2021.
Tru Calling
Tru Calling (2003-2005) is a Fox supernatural drama created by Jon Harmon Feldman, starring Eliza Dushku as morgue worker Tru Davies, who relives days to prevent deaths; canceled after 26 episodes across 2 seasons.
Tru Skool
Tru Skool is the stage name of Sukhjit Singh Olk, a Panjabi folk and hip-hop producer from Derby, England, prominent in UK bhangra since 2004.
Tru-cut biopsy
Tru-cut biopsy is a core needle biopsy technique in which a side-notch cutting needle, advanced manually or spring-loaded, removes a half-cylindrical tissue core for diagnosis.
Tru-D SmartUVC
Tru-D SmartUVC, short for Thorough Room Ultraviolet Disinfection, is a portable whole-room ultraviolet-C disinfection system for hospitals, launched in 2007 by Lumalier of Memphis, Tennessee, and part of PDI since 2019.
Tru64 UNIX
Tru64 UNIX is a discontinued 64-bit UNIX operating system for the DEC Alpha platform, developed by Digital Equipment Corporation and formerly called DEC OSF/1 and Digital UNIX.
Truancy
Truancy: unexcused, unauthorized school absence by compulsory-age students, defined by state or national law. Distinct from chronic absenteeism (10%+ missed days); historically tied to compulsory schooling enforcement; interventions show small positive effects.
TruArc Partners
TruArc Partners is a New York-based middle-market private equity firm founded in 2020 as successor to Snow Phipps Group, investing in specialty manufacturing and business services.
Truc (France)
Truc, also known as Le Truc, is a French trick-taking card game of the truc and truco family, played in Roussillon, the Pays Basque, Poitou, and Sarthe.
Truc (Truc)
Truc (Truque, Trut) is a Catalan and southern French bluffing trick-taking card game of the Put group: Spanish 40-card deck, suits ignored, ranking 3-2-1-12-11-10-7-6-5-4, bets truc/retruc, basis of South American Truco.
Truc Lam Zen school
The Truc Lam Zen school (Thiền phái Trúc Lâm) is a Vietnamese Zen school founded in 1299 by the retired emperor Tran Nhan Tong on Yen Tu mountain.
Trúc Nhân
Trúc Nhân (Nguyễn Trúc Nhân), born 1991 in Bình Định, is a Vietnamese pop singer known for The Voice of Vietnam 2012 and satirical folk-pop hits like Sáng Mắt Chưa.
Truce of 1503 with Lithuania
The Truce of 1503 with Lithuania (Перемирье с Литвой 1503 года) was a six-year armistice between Ivan III and Lithuania, leaving Moscow nineteen towns, about a third of Lithuanian territory.
Truce of Altmark
The Truce of Altmark (rozejm w Starym Targu) was a six-year truce between the Polish–Lithuanian Commonwealth and Sweden, signed on 26 September 1629 at Altmark in Royal Prussia.
Truce of Andrusovo
The Truce of Andrusovo (Андрусовское перемирие) was the 1667 armistice ending the Russo-Polish war of 1654–1667, dividing Ukraine along the Dnieper between Russia and the Commonwealth.
Truce of Deulino (Деулинское перемирие)
Truce of Deulino (Деулинское перемирие, Rozejm w Dywilinie), armistice of 1(11) December 1618 between the Polish-Lithuanian Commonwealth and Russia: 14.5 years, cession of Smolensk and Seversk lands, prisoner exchange, confirmed at Polyanovka 1634.
Truce of Jam Zapolski
The Truce of Jam Zapolski (Ям-Запольское перемирие) was a 1582 truce between Russia and the Polish-Lithuanian Commonwealth that ended their part of the Livonian War.