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Tube Alloys

Tube Alloys: code name of the British wartime atomic bomb program, run by the Directorate of Tube Alloys under Wallace Akers. Grew from the 1940 Frisch-Peierls memorandum and MAUD Committee; gaseous diffusion chosen; absorbed into the Manhattan Project after the August 1943 Quebec Agreement.

Tube furnace

A tube furnace is a laboratory or industrial heating device in which heating elements surround a cylindrical work tube, allowing samples to be heated to controlled temperatures under controlled gases or vacuum.

Tube Investments of India

Tube Investments of India (TII) is a Chennai-based engineering company of the Murugappa Group, founded in 1949, that makes steel tubes, industrial chains, and bicycles, and controls CG Power.

Tube map

The Tube map, also called the London Underground map, is the schematic diagram of the London Underground devised by Harry Beck and first issued to passengers in January 1933.

Tube-based robust model predictive control

Tube-based robust model predictive control (tube MPC) is a robust control method where an ancillary feedback keeps a disturbed system inside a tube around a nominal trajectory.

Tubeless tire

A tubeless tire is a pneumatic tire that holds pressurized air without an inner tube, sealing airtight against the rim itself and standard on most new cars within a few years of 1952.

Tubelight (ट्यूबलाइट) (2017 Hindi film)

Tubelight (ट्यूबलाइट) is a 2017 Hindi war drama directed by Kabir Khan, starring Salman Khan as Laxman and Sohail Khan as Bharat, based on Little Boy and set in 1962; released 23 June 2017, it earned about its ₹100 crore budget.

Tuber

Tuber: a swollen underground stem storage organ, as in potato, formed from a stolon and bearing buds (eyes); distinct from tuberous roots like sweet potato, and controlled by phloem-mobile StSP6A signaling.

Tuber melanosporum

Tuber melanosporum, the Perigord black truffle (syn. Tuber nigrum), is a hypogeous ascomycete forming ectomycorrhizas with oaks and hazels; cultivated since 18th-century France, priced 700–1,350 €/kg, with a 125 Mb genome and heterothallic outcrossing.

Tubercle

Tubercle (dental anatomy): a small enamel elevation on a tooth crown, non-occlusal, unlike a cusp. Examples include the tubercle of Carabelli, mamelons, and the paramolar tubercle described by Bolk.

Tuberculin skin test

The tuberculin skin test (TST) is a diagnostic test for tuberculosis infection in which tuberculin PPD is injected into the skin and the reaction is measured.

Tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is an airborne infectious disease of the lungs; 10.7 million cases and 1.23 million deaths in 2024, with MDR-TB and a quarter of humanity infected.

Tuberculosis of bones or joints

Tuberculosis of bones or joints, or osteoarticular tuberculosis, is infection of the skeleton by Mycobacterium tuberculosis; the spine is most often involved, a condition known as Pott's disease.

Tuberculosis of ear

Tuberculosis of ear, or tuberculous otitis media (TOM), is a rare extrapulmonary TB of the middle ear causing chronic otorrhea and hearing loss; now 0.04–0.9% of chronic suppurative otitis media, treated with anti-TB chemotherapy plus surgery.

Tuberculosis of eye

Ocular tuberculosis (OTB, tuberculosis of eye): intraocular inflammation, mostly uveitis, caused by Mycobacterium tuberculosis via hematogenous spread or hypersensitivity; diagnosed presumptively with IGRA/TST, imaging, and phenotype; treated like pulmonary TB.

Tuberculosis of heart

Tuberculosis of the heart (cardiac tuberculosis): M. tuberculosis infection of cardiac structures, most often the pericardium, rarely the myocardium; diagnosed by bacillus isolation, ADA, Xpert; treated with 6-12 month chemotherapy.

Tuberculosis of the digestive system

Tuberculosis of the digestive system, or gastrointestinal/abdominal TB, is extrapulmonary Mycobacterium tuberculosis infection of gut, peritoneum, or viscera, favoring the ileocecal region and mimicking Crohn's disease.

Tuberculosis of the genitourinary system

Tuberculosis of the genitourinary system (genitourinary tuberculosis, GUTB, ICD-10 A18.1): extrapulmonary TB of the urinary tract and reproductive organs, usually reactivation of latent infection, kidney most affected, diagnosed by culture, PCR, and Xpert MTB/RIF.

Tuberculosis of the musculoskeletal system

Tuberculosis of the musculoskeletal system (skeletal, osteoarticular, bone and joint TB; ICD-11 1B12.4): M. tuberculosis infection of bones, joints, and soft tissues, 1-3% of all TB; Pott's spinal disease is the common form; MRI is the imaging modality of choice.

Tuberculosis of the nervous system

Tuberculosis of the nervous system, or CNS tuberculosis, covers tuberculous meningitis, tuberculoma, and spinal TB caused by Mycobacterium tuberculosis; key facts are its high mortality, difficult diagnosis, 12-month drug therapy, and adjunctive dexamethasone.

Tuberculous lymphadenitis

Tuberculous lymphadenitis (scrofula, king's evil) is the most common extrapulmonary tuberculosis, mainly cervical nodes; diagnosed by FNA, culture, Xpert, histology; treated with 6-month regimens.

Tuberculous meningitis

Tuberculous meningitis (TBM), also called TB meningitis or historically "dropsy on the brain", is the most severe form of tuberculosis: M. tuberculosis invades the subarachnoid space, killing or disabling about half of those affected despite multidrug therapy and corticosteroids.

Tuberculous placenta

Tuberculous placenta (ICD-11 JB63.00) is rare Mycobacterium tuberculosis infection of the placenta, usually hematogenous from maternal bacillemia; it shows neutrophilic villitis more often than granulomas and is a Cantwell criterion for congenital tuberculosis.

Tuberin-type domain

Tuberin-type domain (InterPro IPR018515, Pfam PF03542): a conserved alpha-helical domain of tuberin (TSC2), residues 555-903 in humans, between the TSC1-binding region and GAP domain; found in animals and fungi.

Tuberoinfundibular peptide of 39 residues

Tuberoinfundibular peptide of 39 residues (TIP39, PTH2) is a 39-amino-acid brain neuropeptide purified from bovine hypothalamus as the endogenous ligand of the parathyroid hormone 2 receptor, involved in nociception, stress response, and body temperature regulation.

Tuberous breasts

Tuberous breasts (tubular breasts, snoopy deformity) are a congenital breast anomaly appearing at puberty, marked by a constricted breast base, hypoplasia, and areolar herniation; classified by von Heimburg and Grolleau, correctable surgically with about 20% complications.

Tuberous sclerosis

Tuberous sclerosis complex (TSC), also called Bourneville disease, an autosomal dominant TSC1/TSC2 disorder causing mTOR-driven hamartomas in brain, skin, kidneys, heart, and lungs, with epilepsy in up to 85%.

Tuberous xanthoma

Tuberous xanthoma (xanthoma tuberosum, ICD-11 EB90.21) is a firm, painless red-yellow nodule of foam cells over pressure areas such as elbows, knees, and heels, usually signaling type III hyperlipoproteinemia or familial hypercholesterolemia.

Tubi

Tubi is a free ad-supported streaming (AVOD) service founded in 2014, owned by Fox Corporation's Tubi Media Group, with 110 million monthly active users, a 350,000-title library, and Super Bowl LIX streaming reaching 15.5 million peak viewers.

Tubifex

Tubifex, sludge worms, is a genus of tube-dwelling freshwater oligochaete annelids (Naididae, Tubificinae) with about 15-20 species; type species Tubifex tubifex, a pollution-tolerant bioindicator and host of Myxobolus cerebralis.