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Edgepedia

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Type IA topoisomerases

Type IA topoisomerases are enzymes that cleave one DNA strand to relax negatively supercoiled DNA, including bacterial topoisomerase I and III and human TOP3A and TOP3B.

Type Iax supernova

A Type Iax supernova is a peculiar thermonuclear stellar explosion similar to Type Ia but fainter, with lower ejecta velocities, defined in 2013 from the prototype SN 2002cx.

Type IB topoisomerase

Type IB topoisomerase (Topo IB), the eukaryotic topoisomerase I family, relaxes DNA supercoils by nicking one strand, forming a 3'-phosphotyrosyl intermediate, and controlled rotation; ATP- and Mg2+-independent; camptothecin drug target.

Type Ic supernova

A Type Ic supernova (SN Ic) is a core-collapse supernova of a massive star stripped of its hydrogen and helium envelopes, so its spectrum shows neither element's lines.

Type Ic-BL supernova

A Type Ic-BL supernova, or broad-lined Type Ic, is a rare core-collapse supernova with very broad spectral lines, and the only type linked to long gamma-ray bursts.

Type II Cepheid

A Type II Cepheid is an old, low-mass Population II pulsating variable star with periods of 1 to 100 days, used to measure distances to old stellar populations.

Type II hypersensitivity

Type II hypersensitivity (antibody-mediated cytotoxic hypersensitivity) is tissue injury caused by IgG or IgM antibodies binding cell-surface or extracellular-matrix antigens, via complement, phagocytosis, or ADCC; examples include autoimmune hemolytic anemia, transfusion reactions, Goodpasture syndrome, and pemphigus.

Type II restriction endonuclease subunit R

Subunit R of type II restriction endonucleases, the R.EcoRI-type restriction polypeptide, is the PD...D/EXK catalytic chain of homodimeric Mg2+-dependent enzymes that cleave DNA within their 4–8 bp recognition sites without ATP, unlike type I HsdR subunits.

Type II restriction enzyme NlaIII/ICEA1

NlaIII (R.NlaIII), a Type II restriction endonuclease from Neisseria lactamica, cuts 5′-CATG-3′ after the G leaving a 4-base 3′ overhang; its family includes H. pylori iceA1.

Type II restriction enzymes

Type II restriction enzymes are nucleases that recognize short DNA sequences and cut at a fixed position. They are used in genome editing, Golden Gate Assembly, and nucleic acid analysis.

Type II secretion system protein GspI

GspI (XcpV in Pseudomonas aeruginosa) is a minor pseudopilin of the bacterial type II secretion system; it nucleates the GspI-J-K pseudopilus tip complex and is essential for secretion.

Type II submarine

The Type II was a class of small coastal submarines built for the German Kriegsmarine in the 1930s and 1940s, the first U-boats built in Germany after the Treaty of Versailles.

Type II supernova

A Type II supernova is a stellar explosion whose spectrum shows hydrogen, produced when a massive star's iron core collapses, leaving a neutron star or black hole.

Type IIb supernova

A Type IIb supernova is a core-collapse supernova whose progenitor retains little hydrogen; early hydrogen lines fade within weeks into a Type Ib-like spectrum, as in SN 1993J in M81.

Type IIB superstring theory

Type IIB superstring theory is one of the two ten-dimensional type II superstring theories, a chiral theory with 32 supercharges whose low-energy limit is type IIB supergravity.

Type III ferro-chrome cassette tape

Type III ferro-chrome (FeCr) cassette tape is a compact cassette format with a ferric base and chromium dioxide top layer, introduced by Sony in 1973.

Type III hypersensitivity

Type III hypersensitivity (immune complex disease), a Gell and Coombs class, in which IgG/IgM bind soluble antigen; deposited complexes activate complement, causing Arthus reaction, serum sickness, SLE, and glomerulonephritis.

Type III restriction enzyme

A Type III restriction enzyme (EC 3.1.21.5) is a bacterial enzyme that recognizes a short DNA sequence and cuts DNA 25 to 27 base pairs away, needing two recognition sites.

Type III secretion system effector

A type III secretion system effector is a bacterial protein injected into host cells by a type III secretion system, where it manipulates host processes to aid the bacterium.

Type III secretion system effector SseG-like

SseG (SseG-like) is a Salmonella SPI-2 type III secretion system effector that, with SseF, binds host ACBD3 to anchor the Salmonella-containing vacuole at the Golgi network, enabling intracellular replication.

Type III secretion system filament chaperone CesA

CesA, also called CesAB, is the type III secretion system chaperone of enteropathogenic E. coli that traps the EspA filament protein as a monomer, preventing premature polymerization.

Type III secretion system, AvrPto

AvrPto (avrPto1, PSPTO_RS20745) is a type III secretion effector of Pseudomonas syringae pv. tomato DC3000; a three-helix-bundle kinase inhibitor targeting FLS2, EFR, and BAK1, recognized by tomato Pto-Prf immunity.

Type III secretion system, Yop virulence translocation protein R-like

Yop virulence translocation protein R-like (IPR005773, SctR; archetype YscR) is a conserved inner membrane protein family of the bacterial type III secretion export apparatus, homologous to flagellar FliP and essential for Yop secretion in Yersinia.

Type III secretion systems effector SseF-like

SseF-like (InterPro family) type III secretion effectors, exemplified by Salmonella SPI-2 effector SseF: membrane-integral proteins that, with SseG, position the Salmonella-containing vacuole at the Golgi, build SIFs, and bind host ACBD3 and CIC.

Type IIn supernova

A Type IIn supernova (SN IIn) is a supernova whose narrow hydrogen emission lines come from ejecta colliding with dense circumstellar material; Eric Schlegel defined the class in 1990.

Type inference

Type inference, also known as type reconstruction or type deduction, is the process by which a compiler determines an expression's type without explicit programmer annotations, as in ML and Haskell.

Type Inspection Authorization

The Type Inspection Authorization (TIA) is an FAA document, issued on Form 8110-1, that authorizes the conformity inspections, airworthiness inspections, and flight tests required for Type Certificate certification.

Type IV hypersensitivity

Type IV hypersensitivity (delayed-type hypersensitivity) is T cell-mediated, antibody-independent inflammation peaking 48-72 hours after antigen re-exposure; examples include contact dermatitis, SJS/TEN, DRESS, tuberculin reaction, and transplant rejection, diagnosed by patch testing.

Type IV metal cassette tape

Type IV metal cassette tape, sold simply as "metal", is the highest-performance class of the compact cassette, using pure metal particles instead of oxides; it reached the market in 1979.

Type IV methyl-directed restriction enzyme EcoKMcrBC

EcoKMcrBC (McrBC), a Type IV methyl-directed GTP-dependent restriction endonuclease of E. coli K-12, encoded by mcrB and mcrC, cleaves DNA at paired RmC sites 40-3,000 bp apart, targeting methylated cytosine.