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Bacterial Ig-like domain 13
Bacterial Ig-like domain 13 (InterPro IPR044016) is a bacterial immunoglobulin-like (Big) protein domain family found in bacterial surface proteins and phage receptor-binding proteins, with 3 proteins and 21 hits in the Phage RBP Database.
Bacterial Ig-like domain 14
Bacterial Ig-like domain 14 (Big_14, Pfam PF20251) is a Pfam protein domain family of bacterial immunoglobulin-like domains, one of several numbered Big families found in bacterial surface proteins; specific functions are not yet characterized.
Bacterial Ig-like domain, group 2
Bacterial Ig-like domain, group 2 (Big2, IPR003343; CDD BID_2/smart00635) is an immunoglobulin-like beta-sandwich domain found mainly in bacterial and phage surface proteins such as intimins and phage lambda tail tube protein, and also in eukaryotic proteins like human POM210.
Bacterial initiation factor
Bacterial initiation factors IF1, IF2, IF3 (infA, infB, infC) are the three proteins bacteria use to start translation, versus 12+ in eukaryotes; IF2 is a GTPase recruiting fMet-tRNA, IF3 the fidelity factor.
Bacterial iron homeostasis
Bacterial iron homeostasis is the set of sensing and rationing mechanisms bacteria use to keep intracellular iron in a narrow range, centered on the Fur protein and Fur-repressed small RNAs like RyhB.
Bacterial leaf blight of rice
Bacterial leaf blight of rice is a serious bacterial disease caused by Xanthomonas oryzae pv. oryzae, which can cut yields by 10 to 50 percent.
Bacterial Load
Bacterial load is the quantity of bacteria in a sample such as blood, sputum, or a wound, measured by culture or qPCR and often linked to mortality risk.
Bacterial meningitis
Bacterial meningitis: infection of the brain and spinal cord lining, also called bacterial infection of the meninges. Caused by S. pneumoniae, N. meningitidis, Hib, GBS; treated with urgent antibiotics; vaccines cut US incidence 55%.
Bacterial myelitis
Bacterial myelitis (ICD-11 1D02.0) is spinal cord inflammation caused by bacteria, commonly Mycoplasma pneumoniae, Mycobacterium tuberculosis, Treponema pallidum, or Brucella, causing paraparesis, sensory loss, and sphincter dysfunction.
Bacterial myositis
Bacterial myositis (purulent or suppurative myositis, ORPHA:206994, ICD-10 M60.0) is a rare acquired skeletal muscle disease: diffuse bacterial muscle infection without intramuscular abscess, mostly streptococcal, causing pain, swelling, weakness, rhabdomyolysis, myonecrosis, or gangrene.
Bacterial pneumonia
Bacterial pneumonia, a lung infection in which bacteria such as Streptococcus pneumoniae invade the alveoli; leading infectious killer of children, treated with antibiotics like amoxicillin, prevented by pneumococcal vaccines.
Bacterial protein export chaperone SecB
SecB, bacterial protein export chaperone; ATP-independent homotetramer (~69 kDa) of E. coli and other gram-negatives; binds unfolded preproteins with low specificity, high affinity, and targets them to SecA at the Sec translocon.
Bacterial purine repressor, N-terminal
Bacterial purine repressor, N-terminal: the DNA-binding domain of PurR, a LacI-family (E. coli, 52 aa, HTH plus hinge helix) or winged-helix (B. subtilis) regulator controlling purine biosynthesis genes via hypoxanthine, guanine, or PRPP effectors.
Bacterial RecJ exonuclease
Bacterial RecJ exonuclease, a DHH-family 5'→3' single-stranded-DNA-specific exonuclease of E. coli and most bacteria, essential in homologous recombination, mismatch repair, and end resection; distinct from ExoI and absent in Actinobacteria.
Bacterial ribosomal protein S1
Bacterial ribosomal protein S1 (bS1, gene rpsA) is the largest 30S subunit protein, 557 residues in E. coli, with six OB-fold S1 domains. It recruits mRNA to the ribosome, unwinds structured 5' UTRs, and acts in trans-translation; absent from low-GC Gram-positive bacteria and archaea.
Bacterial RNA polymerase
Bacterial RNA polymerase (RNAP, DNA-directed RNA polymerase, EC 2.7.7.6): the α2ββ′ω core enzyme plus sigma factors that transcribes all bacterial RNA; rifamycin antibiotic target with rpoB-mediated resistance.
Bacterial small RNA
Bacterial small RNA (sRNA), 50–350 nt regulatory RNAs that base-pair with mRNAs or bind proteins, often aided by the Hfq chaperone, controlling stress, metabolism, virulence, and antibiotic resistance; includes cis/trans-encoded and dual-function peptide-coding sRNAs.
Bacterial sRNA discovery methods
Bacterial sRNA discovery methods combine genome-wide transcriptomics such as dRNA-seq and RNA-seq, computational gene prediction, and experimental validation to identify small regulatory RNAs in bacteria.
Bacterial taxonomy
Bacterial taxonomy: classification, naming, and identification of bacteria and archaea under the ICNP, from phenotype and 16S rRNA eras to ANI-based genomics, GTDB, and the SeqCode for uncultivated taxa.
Bacterial transcription
Bacterial transcription is the copying of bacterial DNA into messenger RNA by RNA polymerase, whose sigma factors recognize promoters; the enzyme is also a proven target for antibiotics.
Bacterial transcriptional activator domain
BTAD (bacterial transcriptional activator domain; Pfam PF03704, InterPro IPR005158) is a seven-helix domain in SARP-family regulators such as AfsR, DnrI, and EmbR, where it supports dimerization and RNA polymerase recruitment for antibiotic gene activation.
Bacterial translation
Bacterial translation: protein synthesis on 70S ribosomes via initiation, elongation, termination, recycling. Uses three factors IF1, IF2, IF3, fMet-tRNA, and Shine-Dalgarno/16S rRNA pairing for start codon selection.
Bacterial turbulence
Bacterial turbulence is the self-organized chaotic flow in dense suspensions of swimming bacteria, where morphing eddies and jets span scales tens to hundreds of times a cell's size.
Bacterial Typing Techniques
Bacterial typing techniques are laboratory procedures for distinguishing strains within a bacterial species, spanning phenotypic methods (serotyping, phage typing, biotyping) and genotypic methods (PFGE, MLST, WGS), used in outbreak investigation and surveillance.
Bacterial vaginosis
Bacterial vaginosis (BV), a vaginal dysbiosis replacing Lactobacillus with Gardnerella and anaerobic biofilm bacteria, is the most common cause of vaginal discharge; treated with metronidazole or clindamycin, it recurs in over 50% of women.
Bacterial virulence
Bacterial virulence: the relative capacity of a microorganism to damage a host. Also covers virulence factors, pathogenicity islands, trade-off evolution, and the Brucella VirB T4SS with VirJ as a worked example.
Bacterial virulence protein VirB8-like
VirB8-like proteins are conserved bitopic inner membrane assembly factors of bacterial type IV secretion systems, with an NTF2-like periplasmic domain, physiologically relevant dimerization, and a validated small-molecule drug target interface.
Bacterial/plant glycogen synthase
Bacterial/plant glycogen synthase (G(S)S): GT5-family α-1,4-glucan synthases, bacterial GlgA and plant starch synthases, EC 2.4.1.21, using ADP-glucose, unregulated by phosphorylation, unlike animal GT3 UDP-glucose enzymes.
Bactericera cockerelli
Bactericera cockerelli, the potato or tomato psyllid (Paratrioza cockerelli), is an American Triozidae psyllid pest of Solanaceae crops and vector of Candidatus Liberibacter solanacearum, cause of zebra chip disease, now also in New Zealand and Australia.
Bacteriochlorophyll
Bacteriochlorophyll (BChl) is a class of light-absorbing pigments used by anoxygenic photosynthetic bacteria, occurring in six known types whose absorption extends into the near infrared beyond plant chlorophylls.