# Leigh H. Simmons
**Leigh H. Simmons** (Leigh Holman Simmons) is an American internal medicine physician at [Massachusetts General Hospital](https://www.edgepedia.org/massachusetts-general-hospital) (MGH) in Boston, where she directs the MGH Health Decision Sciences Center and studies shared decision making between patients and clinicians.[1](https://orcid.org/0000-0002-2375-8485) • [2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) She is a first author of the Case Records of the Massachusetts General Hospital, the journal's long-running clinicopathological case series, including "Case 11-2025: A 79-Year-Old Woman with Cough and Weight Loss" (2025).[3](https://pubmed.ncbi.nlm.nih.gov/40239071/)
| Key facts | |
|---|---|
| Specialty | Internal medicine, board certified by the American Board of Internal Medicine[2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) |
| Research center | Medical director, MGH Health Decision Sciences Center, affiliated from April 2010[1](https://orcid.org/0000-0002-2375-8485) • [2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) |
| Teaching | Directs the internal medicine clerkship for Harvard Medical School students at MGH[4](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/) |
| Signature work | "Case 11-2025: A 79-Year-Old Woman with Cough and Weight Loss", *New England Journal of Medicine*, 2025, first author[3](https://pubmed.ncbi.nlm.nih.gov/40239071/) |
## Education and training
Simmons is a native of Tennessee.[2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) She then trained in internal medicine at Massachusetts General Hospital from July 2004 to July 2007, and served as a chief resident there in 2007–08.[1](https://orcid.org/0000-0002-2375-8485) • [2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) She is board certified in internal medicine by the [American Board of Internal Medicine](https://www.edgepedia.org/american-board-of-internal-medicine).[2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932)
## Career at Massachusetts General Hospital
Her clinical practice is with the Internal Medicine Associates, where she focuses on the care of the medically complex patient.[4](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/) • [6](https://thepcc.org/profiles/leigh-simmons/)
There she studies the use of decision aids to help patients and clinicians in the shared decision making process.[2](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932) She is also on the staff of the John D. Stoeckle Center for Primary Care Innovation, where a profile by the Primary Care Collaborative describes her as a physician fellow studying video decision aids.[4](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/) • [6](https://thepcc.org/profiles/leigh-simmons/)
She is a medical student educator and directs the internal medicine clerkship for Harvard Medical School students at Massachusetts General Hospital.[4](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/) Her ORCID record dates this clerkship directorship to July 2004, the same month her residency began; the institutional profiles that describe the role give no start date, so the earlier date is not settled.[1](https://orcid.org/0000-0002-2375-8485) • [4](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/)
## Representative work
In "Case 11-2025: A 79-Year-Old Woman with Cough and Weight Loss", published in the *New England Journal of Medicine* on April 17, 2025 (volume 392, pages 1532–1543), she is first author, writing from the Department of Medicine at MGH and Harvard Medical School; the authorship spans the hospital's departments of Medicine, Radiology, and [Pathology](https://www.edgepedia.org/pathology), and PubMed indexes the article as a case report.[3](https://pubmed.ncbi.nlm.nih.gov/40239071/) ([doi:10.1056/NEJMcpc2412520](https://doi.org/10.1056/nejmcpc2412520))
Two earlier Case Records belong to the same series: "Case 33-2016. A 30-Year-Old Woman with Severe Lower Abdominal Pain and Chills" (October 27, 2016), which she wrote as first author and which describes a patient with tachycardia, bilateral lower-quadrant tenderness, leukocytosis, an elevated CA-125 level, and adnexal cysts on imaging[7](https://www.nejm.org/doi/full/10.1056/NEJMcpc1609308).
## The Case Records tradition
The Case Records are the published form of the MGH clinicopathological conference, printed regularly in the *New England Journal of Medicine* since 1924.[8](https://www.massgeneral.org/pathology/education-and-training/history-of-the-our-case-records) At each conference a guest physician deduces the diagnosis of an anonymous, actual MGH patient from the history and preliminary test results alone; a member of the MGH Pathology Service then presents the confirmed diagnosis with evidence.[8](https://www.massgeneral.org/pathology/education-and-training/history-of-the-our-case-records) In 2024 the journal marked the series' centenary, crediting it with helping to guide medical practice and build a global community of clinicians.[9](https://www.nejm.org/doi/full/10.1056/NEJMms2405389)
According to the MGH Pathology chapter on the clinicopathological conferences, the journal's authorship policy requires authors to have a speaking role at the conference and to prepare the text, references, and images, and requires clinical discussants to be faculty members rather than trainees; trainees may present the case history and follow-up and are named in the body of the record.[10](https://www.massgeneral.org/assets/mgh/pdf/pathology/pathology_chap24.pdf) The series' stated mission remains an update to its original concept: educating physicians in new approaches to diagnosis, classification, and treatment of disease through the study of actual cases.[10](https://www.massgeneral.org/assets/mgh/pdf/pathology/pathology_chap24.pdf)
## Shared decision making and other research
Beyond the case series, her research concerns how patients and clinicians make medical decisions together. According to a 2016 study in *Teaching and Learning in Medicine*, on which she served as corresponding author, a workshop curriculum taught shared decision making to internal medicine residents for four common chronic conditions: diabetes, depression, hypertension, and hyperlipidemia.[11](https://doi.org/10.1080/10401334.2016.1146600) [One hundred](https://www.edgepedia.org/one-hundred) thirty internal medicine and medicine-pediatrics residents attended 8 workshops over a 4-month period; 89.7 percent rated the workshop excellent or very good, and 93.5 percent said they would change their practice based on what they learned.[11](https://doi.org/10.1080/10401334.2016.1146600) Decision Worksheets for the four conditions were downloaded almost 1,200 times in the first 8 months after the workshops.[11](https://doi.org/10.1080/10401334.2016.1146600)
She co-authored a 2022 paper in the *Journal of General Internal Medicine* on colorectal cancer screening during the COVID-19 pandemic.[12](https://doi.org/10.1007/s11606-022-07642-x)
## Record through 2026
Her ORCID record lists 27 works, and she remains active in both strands of her output.
## References
1. [Leigh Simmons (0000-0002-2375-8485) – ORCID](https://orcid.org/0000-0002-2375-8485)
2. [Leigh Simmons, MD | Mass General Brigham](https://www.massgeneralbrigham.org/en/doctors/s/leigh-simmons-2999932)
3. [Case 11-2025: A 79-Year-Old Woman with Cough and Weight Loss – PubMed](https://pubmed.ncbi.nlm.nih.gov/40239071/)
4. [Leigh Simmons, MD – MGH Health Decision Sciences Center](https://mghdecisionsciences.org/about-us-home/faculty-staff/leigh-simmons-md/)
5. [Dr. Leigh Holman Simmons M.D. – NPI 1437279478](https://npi-lookup.org/1437279478-leigh-holman-simmons-ma)
6. [Leigh Simmons – Primary Care Collaborative](https://thepcc.org/profiles/leigh-simmons/)
7. [Case 33-2016, A 30-Year-Old Woman with Severe Lower Abdominal Pain and Chills – NEJM](https://www.nejm.org/doi/full/10.1056/NEJMcpc1609308)
8. [History of the Our Case Records – MGH Pathology](https://www.massgeneral.org/pathology/education-and-training/history-of-the-our-case-records)
9. [Building a Community of Medical Learning, A Century of Case Records – NEJM](https://www.nejm.org/doi/full/10.1056/NEJMms2405389)
10. [The Clinicopathological Conferences (CPCs) – MGH Pathology chapter 24](https://www.massgeneral.org/assets/mgh/pdf/pathology/pathology_chap24.pdf)
11. [Shared Decision Making in Common Chronic Conditions: Impact of a Resident Training Workshop](https://doi.org/10.1080/10401334.2016.1146600)
12. [Colorectal Cancer Screening During the COVID-19 Pandemic – Journal of General Internal Medicine](https://doi.org/10.1007/s11606-022-07642-x)
13. [Report reviews 10 years of shared decision making at Massachusetts General Hospital](https://www.brightsurf.com/news/19V354J8/report-reviews-10-years-of-shared-decision-making-at-massachusetts-general-hospital.html)
---
*Topic: Encyclopedia › Life and health › Life and health scientists › Medical and health researchers › Health services researchers › Quality and patient safety researchers*
*Initially written Sep 21, 2026 · Reviewed: Sep 25, 2026 · Edited: Sep 25, 2026 · Last review: Sep 25, 2026*
*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*
License: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license