# Newpath Partners
Newpath Partners is a Boston-based life-science venture capital firm founded in 2018 by Thomas J. Cahill, a scientist-turned-investor, which forms companies with academic scientists and remains an independent, actively filing fund manager as of September 2026.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) Its SEC Form D records show four fund vehicles filed between 2019 and 2026, with roughly USD 727 million in total amounts sold across the first three.[2](https://fundraisingfox.com/investors/newpath-partners)
| Fact | Detail |
| --- | --- |
| Founded | 2018, by Tom Cahill[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) |
| Headquarters | 800 Boylston Street, Suite 2222, Boston, MA 02199[3](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt) |
| Sector | Life-science venture capital; company formation with academic scientists[4](https://www.prnewswire.com/news-releases/newpath-partners-launches-fund-ii-to-create-life-sciences-companies-301439720.html) |
| Funds | Four vehicles filed 2019–2026; ~$727M sold across Funds I–III per Form D records[2](https://fundraisingfox.com/investors/newpath-partners) |
| Known launches backed | Neumora Therapeutics ($500M, Oct 2021) and Prime Medicine ($315M, Jul 2021)[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) |
| Managing Partner | Thomas J. Cahill, MD, PhD; board member of Prime Medicine[3](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt) |
| Status, Sep 2026 | Operating; fourth fund first filed 2026-05-28[2](https://fundraisingfox.com/investors/newpath-partners) |
## History and people
Founder-led structure. The firm was started in 2018 by Tom Cahill, described by [The Boston Globe](https://www.edgepedia.org/the-boston-globe) as an academic scientist-turned-investor, and raised its second fund within three years of launching.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) Cahill, who holds MD and PhD degrees, is Managing Partner and leads all operations at Newpath, focusing on the formation, strategy, and development of the firm's investments; according to the firm's team page, he sits on the board of all of Newpath's investments.[5](https://newpath-partners.webflow.io/team)
SEC filings make the firm's structure explicit. The reporting group behind its Prime Medicine stake comprises Newpath Partners, L.P., a Delaware limited partnership, its general partner Newpath GP, L.P., and Newpath GP, LLC, of which Cahill is the managing member.[3](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt) The firm's site lists two other investment professionals: Philip J. DeSouza, MD, a Venture Partner who performs the firm's scientific discovery and diligence, and Daniel Yadegar, MD, FACC, who reviews and consults on medical and scientific diligence.[5](https://newpath-partners.webflow.io/team)
## Strategy
Newpath describes itself as life-science investors tackling difficult medical challenges through transformative science and catalytic partnerships, forming companies with academic scientists.[6](https://www.newpath.partners/) Its model is company creation rather than purely passive investing: since 2018 it has partnered with more than 15 scientific founders, according to The Boston Globe.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/)
The firm's press release for Fund II names the academic partners around whom much of that fund would be deployed: Ben Cravatt ([Scripps Research](https://www.edgepedia.org/scripps-research)), Keith Joung ([Massachusetts General Hospital](https://www.edgepedia.org/massachusetts-general-hospital), Harvard Medical School), David Liu (Broad Institute of Harvard and MIT), Siddhartha Mukherjee, Michael Rosbash, Stuart Schreiber, Ron Vale, Jonathan Weissman, and Jim Wells.[4](https://www.prnewswire.com/news-releases/newpath-partners-launches-fund-ii-to-create-life-sciences-companies-301439720.html) The firm's own materials state that Cahill sits on the board of every Newpath investment.[5](https://newpath-partners.webflow.io/team)
## Funds by the numbers
The firm's Form D records, as compiled by an SEC-derived aggregator, show:[2](https://fundraisingfox.com/investors/newpath-partners)
- **Fund I** (Newpath Partners, L.P.): $111,350,000 sold; vintage 2018.[2](https://fundraisingfox.com/investors/newpath-partners)
- **Fund II** (Newpath Partners II, L.P.): $342,525,000 sold; vintage 2021; announced publicly as a $350 million fund in December 2021.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) • [2](https://fundraisingfox.com/investors/newpath-partners)
- **Fund III** (Newpath Partners III, L.P.): $273,407,000 sold; vintage 2023.[2](https://fundraisingfox.com/investors/newpath-partners)
- **Fund IV** (Newpath Partners IV, L.P.): first filed 2026-05-28; no amount sold recorded yet in the compiled data.[2](https://fundraisingfox.com/investors/newpath-partners)
The announced Fund II figure and the filed amount differ by about $7.5 million; the filed Form D amount of $342.5 million is the regulatory record, while $350 million is what the firm announced in its press release and The Boston Globe reported.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/) • [2](https://fundraisingfox.com/investors/newpath-partners) Summing the filed amounts for the first three funds gives roughly $727 million sold as of September 2026.[2](https://fundraisingfox.com/investors/newpath-partners)
## Portfolio and exits
According to the firm's own Fund II announcement, its first fund built a portfolio including Prime Medicine, Chroma Medicine, Kojin Therapeutics, Exo Therapeutics, Kisbee Therapeutics, and Myeloid Therapeutics.[4](https://www.prnewswire.com/news-releases/newpath-partners-launches-fund-ii-to-create-life-sciences-companies-301439720.html) The Boston Globe reports that Newpath participated in two large company launches: the $500 million launch of [Neumora Therapeutics](https://www.edgepedia.org/neumora-therapeutics) in October 2021 and the $315 million launch of Prime Medicine in July 2021.[1](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/)
The firm's Prime Medicine holding is documented in its own SEC filings. As of February 7, 2023, Newpath Partners, L.P. directly held 5,305,679 shares of Prime Medicine common stock, 5.5% of the class based on 97,208,342 shares outstanding as of November 8, 2022, and Cahill sat on Prime Medicine's board.[3](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt) A February 2025 amendment shows the stake grown to 6,105,679 shares, about 800,000 more than two years earlier, but diluted to 4.7% of 131,160,842 shares outstanding as of December 5, 2024.[7](https://www.sec.gov/Archives/edgar/data/1894562/000149315225006876/0001493152-25-006876.txt)
An aggregator derived from Form D filings lists two IPO exits for the firm's portfolio, Prime Medicine (NASDAQ: PRME) and Neumora Therapeutics (NASDAQ: NMRA), and post-2023 board-seat filings at [Chroma Medicine](https://www.edgepedia.org/chroma-medicine) (a $135 million raise filed September 2023), raises of $45.3 million (November 2024) and $40 million (January 2025), and Rinascera Therapeutics (filed October 2025). These specific deal figures come only from the aggregator and are unverified against the underlying filings.[2](https://fundraisingfox.com/investors/newpath-partners)
## Recent developments
The measurable record since 2023 has three parts. First, Fund III, a 2023-vintage vehicle, recorded $273.4 million sold in the compiled Form D data.[2](https://fundraisingfox.com/investors/newpath-partners) Second, the firm's Prime Medicine position grew from 5,305,679 shares in February 2023 to 6,105,679 shares in February 2025, an increase of about 15%, while its percentage stake fell from 5.5% to 4.7%.[3](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt) • [7](https://www.sec.gov/Archives/edgar/data/1894562/000149315225006876/0001493152-25-006876.txt) Third, the firm filed its fourth vehicle, Newpath Partners IV, L.P., on May 28, 2026, continuing the pattern of a new fund roughly every two to three years since 2019.[2](https://fundraisingfox.com/investors/newpath-partners)
## References
1. [Newpath Partners raises $350 million for second life science fund — The Boston Globe (Dec 8, 2021)](https://www.bostonglobe.com/2021/12/08/business/newpath-partners-raises-350-million-second-life-science-fund/)
2. [Newpath Partners — Form D-derived fund data (Fundraising Fox aggregator; LP counts, targets and deal figures unverified)](https://fundraisingfox.com/investors/newpath-partners)
3. [Schedule 13G — Newpath Partners, L.P. and affiliates re: Prime Medicine, Inc. (SEC, filed 2023-02-07)](https://www.sec.gov/Archives/edgar/data/1894562/0001193125-23-027015.txt)
4. [Newpath Partners Launches Fund II to Create Life Sciences Companies — PR Newswire (firm press release, Dec 8, 2021)](https://www.prnewswire.com/news-releases/newpath-partners-launches-fund-ii-to-create-life-sciences-companies-301439720.html)
5. [Newpath Partners — Team (firm website)](https://newpath-partners.webflow.io/team)
6. [Newpath Partners — firm website](https://www.newpath.partners/)
7. [Schedule 13G/A — Newpath Partners, L.P. and affiliates re: Prime Medicine, Inc. (SEC, filed 2025-02-14)](https://www.sec.gov/Archives/edgar/data/1894562/000149315225006876/0001493152-25-006876.txt)
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*Topic: Encyclopedia › Society and history › Economics and business › Finance › Venture capital and private equity › Venture capital firms of the Americas › Healthcare and life sciences investors › Biopharma and biotech investors*
*Initially written Sep 17, 2026 · Edited: Oct 11, 2026; Oct 15, 2026*
*Copyright 2026 EdgeChat AI, a subsidiary of Biostate AI.*
License: Edgepedia Community License 1.0, https://www.edgepedia.org/edgepedia/license