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All articles starting with M

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Meta-World

Meta-World is an open-source benchmark for meta-reinforcement learning and multi-task reinforcement learning, consisting of 50 simulated robotic manipulation tasks performed by a Sawyer robot arm.

Meta–Google Cloud compute deal

The Meta–Google Cloud compute deal is a six-year agreement, reported in August 2025, under which Meta will spend more than $10 billion on Google Cloud servers, storage, and networking, mainly for AI infrastructure.

Meta–Manus takeover unwind

The Meta–Manus takeover unwind was the forced reversal of Meta's roughly $2 billion acquisition of AI startup Manus, ordered by China's NDRC in April 2026.

Meta–Scale AI deal

The Meta–Scale AI deal was a June 2025 transaction in which Meta invested $14.3 billion for a 49 percent non-voting stake in Scale AI, hiring founder Alexandr Wang.

Meta's retreat from open weights

Meta's retreat from open weights was the 2025–26 shift in which Meta, long the standard-bearer for open Llama models, launched the closed, API-only Muse Spark, then partially reopened with Muse Glimmer in 2026.

Metabarcoding

Metabarcoding, also called DNA metabarcoding, is a method that identifies many species at once from a single bulk or environmental sample such as soil, water, or faeces, introduced in 2012.

Metabarons

Metabarons (La Caste des Méta-Barons), also The Metabarons First Cycle, is a space-opera comic by Jodorowsky and Giménez (1992-2003, Les Humanoïdes Associés), a spin-off of The Incal about a warrior dynasty whose heirs kill their fathers.

Metabase

Metabase is an open-source business intelligence platform founded in 2014 in San Francisco that connects to existing databases, letting non-technical users build queries, charts, and dashboards without writing SQL.

Metabo

Metabo is a German power tool manufacturer founded in Nürtingen in 1924, known for cordless power tools, battery technology, and the Cordless Alliance System; it has belonged to Japan's Koki Holdings since 2016.

Metabolic acidosis

Metabolic acidosis: primary fall in blood bicarbonate with compensatory low PCO2, classified as high anion gap (ketoacidosis, lactic acidosis, renal failure, toxins) or normal gap (bicarbonate loss); diagnosed by ABG and electrolytes, treated by cause.

Metabolic Activation

Metabolic activation (bioactivation): enzymatic conversion of an exogenous substance into an active metabolite, mainly by cytochrome P450 enzymes; beneficial for prodrugs like levodopa, harmful when reactive metabolites cause liver injury.

Metabolic alkalosis

Metabolic alkalosis, a primary rise in serum bicarbonate (HCO3-) raising blood pH, caused by diuretics, vomiting, hypokalemia, or mineralocorticoid excess; classified chloride-responsive or resistant; common in ICU, treated with saline, potassium, or acetazolamide.

Metabolic bone disease of prematurity

Neonatal osteopenia, also called osteopenia of prematurity or metabolic bone disease of prematurity, is reduced bone mineralization in preterm infants after interrupted third-trimester calcium and phosphorus accretion, affecting up to 30-32% of very low birth weight infants.

Metabolic Clearance Rate

Metabolic Clearance Rate, also called Total Body Clearance Rate, is a pharmacokinetic measure of the volume of fluid cleared of a drug by metabolism per unit time.

Metabolic control analysis

Metabolic control analysis (MCA), founded by Kacser and Burns (1973) and Heinrich and Rapoport (1974), is a framework quantifying how enzyme activities control metabolic fluxes via control, elasticity, and response coefficients, replacing the rate-limiting step concept with shared control.

Metabolic disorder

Metabolic disorder, including inborn errors of metabolism (IEM), is a disruption of normal metabolism usually from a missing enzyme; over 2000 inherited types exist, about 1 in 1965 live births, detectable by newborn screening.

Metabolic engineering

Metabolic engineering rewires cellular metabolism, usually in microbes, using recombinant DNA to boost production of fuels, chemicals, and drugs; the field was formally defined in 1991.

Metabolic Equivalent

Metabolic equivalent (MET), metabolic equivalent of task: unit expressing physical activity intensity as a multiple of resting metabolic rate, 1 MET = 3.5 mL O2/kg/min; classifies sedentary to vigorous activity and anchors the Compendium of Physical Activities.

Metabolic flux analysis

Metabolic flux analysis (MFA), including 13C-MFA, estimates intracellular metabolic reaction rates from stable isotope tracer labeling data plus extracellular rates using mathematical network models; distinct from flux balance analysis, it is central to metabolic engineering and cancer metabolism research.

Metabolic labeling

Metabolic labeling is a bench biology technique that feeds isotope-labeled nutrients to living cells or organisms, letting mass spectrometry track and quantify newly synthesized proteins.

Metabolic network modelling

Metabolic network modeling, also known as metabolic network reconstruction and simulation, is the mathematical representation of biochemical reactions in a cell, used to predict metabolite and flux behavior.

Metabolic pathway

Metabolic pathway: a sequence of connected enzyme-catalyzed reactions converting a substrate to a product; exemplified by glycolysis (Embden–Meyerhof–Parnas pathway, net 2 ATP per glucose), regulated at key enzymes and shaped by thermodynamic constraints.

Metabolic Reprogramming

Metabolic reprogramming, also called metabolism reprogramming or metabolic programming, is the cellular rewiring of metabolism to sustain energy production under stress; best known as the Warburg effect in cancer, it also occurs in activated immune cells and chronic diseases.

Metabolic screening

Metabolic screening is testing of newborn heel-prick blood spots, mostly by tandem mass spectrometry, to detect treatable inborn errors of metabolism such as PKU and MCADD before symptoms appear.

Metabolic syndrome

Metabolic syndrome, also called syndrome X or insulin resistance syndrome, is a cluster of abdominal obesity, high triglycerides, low HDL, high blood pressure, and high fasting glucose; three of five components diagnose it and it raises diabetes risk about fivefold.

Metabolic waste

Metabolic waste: byproducts of metabolism, chiefly carbon dioxide and the nitrogenous wastes ammonia, urea, and uric acid, whose excretion routes and water costs differ between aquatic and terrestrial animals.

Metabolism

Metabolism: the body's enzyme-catalyzed chemical processes converting or using energy, divided into catabolism and anabolism; covers ATP, tissue metabolic rates, energy expenditure measurement, and metabolic disease.

Metabolism of lipids

Metabolism of lipids is the set of biochemical processes by which organisms synthesize, break down, and transport lipids, which serve as energy stores, membrane components, and signaling agents.

Metabolism of polyamines

Metabolism of polyamines is the network of reactions by which cells synthesize, interconvert, and degrade the polyamines putrescine, spermidine, and spermine, essential polycations whose dysregulation is linked to cancer.

Metabolism of porphyrins

Metabolism of porphyrins (porphyrin metabolism): the biochemistry of tetrapyrrole macrocycles, chiefly the eight-step mitochondrial and cytosolic heme biosynthesis pathway, its regulation in liver and bone marrow, heme degradation to bilirubin, and the porphyrias.