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All articles starting with M

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Methoprene

Methoprene (Altosid, ZR-515) is a juvenile hormone analog insect growth regulator, first EPA-registered in 1975, used as a mosquito larvicide, flea treatment, and stored-grain protectant; s-methoprene is the active isomer.

Methoprotryne

Methoprotryne (methoprotryn, Gesaran, CAS 841-06-5) is an obsolete methylthiotriazine herbicide introduced by Geigy in 1965 for postemergence grass weed control in winter cereals; a photosystem II inhibitor, not approved in the EU and classified obsolete by WHO.

Methotrexate

Methotrexate (MTX, amethopterin) is an antifolate antimetabolite inhibiting dihydrofolate reductase, used for ALL and other cancers, rheumatoid arthritis, psoriasis, and ectopic pregnancy; approved in the US for cancer in 1955.

Methotrexate and prednisone combination therapy

Methotrexate and prednisone combination therapy pairs methotrexate with prednisone so prednisone controls inflammatory symptoms while methotrexate builds its effect, used mainly in early rheumatoid arthritis and giant-cell arteritis.

Methotrexate and vinblastine regimen

The methotrexate and vinblastine regimen is a two-drug intravenous chemotherapy combination used mainly for advanced urothelial carcinoma and desmoid-type fibromatosis, and forms the backbone of MVAC.

Methotrexate regimen

A methotrexate regimen is a dosing protocol for the antifolate drug methotrexate, given alone or with other agents to treat cancers, rheumatoid arthritis, and psoriasis, with doses spanning several thousand-fold.

Methotrexate toxicity

Methotrexate toxicity (ORPHA:565782) is a rare intoxication from the antifolate methotrexate: renal tubular crystal injury causing acute kidney injury, plus myelosuppression, mucositis, and hepatotoxicity, managed with leucovorin and glucarpidase.

Methotrexate-associated lymphoproliferative disorders

Methotrexate-associated lymphoproliferative disorders (MTX-LPD, OIIA-LPD) are EBV-related lymphoid proliferations or lymphomas arising in autoimmune disease patients on methotrexate, often regressing after drug withdrawal.

Methoxamine

Methoxamine is a synthetic sympathomimetic amine used as the vasopressor methoxamine hydrochloride to raise blood pressure during anesthesia, formerly sold as Vasoxyl and discontinued in the United States.

Methoxetamine

Methoxetamine, also known as Mexxy, is a synthetic ketamine analog dissociative drug first identified in the United Kingdom in 2010 and internationally controlled in 2016.

Methoxychlor

Methoxychlor (DMDT, Marlate, Metox), CAS 72-43-5, an organochlorine DDT-analog insecticide registered in 1948, estrogenic via the metabolite HPTE, banned in the US in 2003 and not approved in the EU.

Methoxyfenozide

Methoxyfenozide (Intrepid, Prodigy) is a diacylhydrazine ecdysone-agonist insecticide, discovered 1990 by Rohm and Haas, controlling lepidopteran larvae via premature lethal molt; EU approval expired and it was deleted from the approved list in 2026.

Methoxyflurane

Methoxyflurane (Penthrane, Penthrox, green whistle) is a volatile fluorinated hydrocarbon anesthetic introduced in 1960, withdrawn for anesthesia by the late 1970s over fluoride-mediated nephrotoxicity, and now used as a self-administered 3 mL inhaled analgesic in Australasia and Europe.

Methsuximide

Methsuximide (Celontin), an anticonvulsant succinimide chemically known as N,2-dimethyl-2-phenylsuccinimide, treats absence seizures refractory to other drugs; FDA-approved 1957 by Parke-Davis, active via N-desmethylmethsuximide metabolite.

Methuen Treaty

The Methuen Treaty was a 1703 commercial agreement between Portugal and England, signed at Lisbon, admitting English woollens and giving Portuguese wines a duty one-third below French wines.

Methusastartus

Methusastartus, also transmitted as Methustratos, was a king of Tyre after Abdastartus and before Astarymus; his name and dates rest on derived king lists, since Josephus's text leaves the reign unnamed.

Methuselah

Methuselah, also known as Metushelach, is an antediluvian patriarch in the Hebrew Bible, the son of Enoch and grandfather of Noah, recorded as living 969 years.

Methuselah (lungfish)

Methuselah is an Australian lungfish (Neoceratodus forsteri) at Steinhart Aquarium, San Francisco, since November 1938; DNA dating puts her at 93 ± 9 years, the world's oldest living aquarium fish.

Methven, New Zealand

Methven is a small alpine service town on the Canterbury Plains, New Zealand, 95 km west of Christchurch, gateway to Mt Hutt ski field; population 1,977 (2023), fastest-growing town in Ashburton District.

Methyclothiazide

Methyclothiazide (Enduron, Aquatensen) is a thiazide diuretic and sodium chloride symporter inhibitor for hypertension and edema, about 100 times more potent per mg than chlorothiazide, excreted unchanged in urine; US products are discontinued.

Methyl acetate

Methyl acetate, also called methyl ethanoate, is a colorless, flammable ester liquid with a fruity odor, used as a solvent for resins, oils, and lacquers.

Methyl acrylate

Methyl acrylate, also known as methyl propenoate, is the methyl ester of acrylic acid, a volatile, highly flammable liquid produced in large volumes as a monomer for acrylic and modacrylic fibers.

Methyl anthranilate

Methyl anthranilate, also called methyl 2-aminobenzoate, is a volatile ester with a strong grape-like odor, the chief compound in artificial grape flavoring and a commercial bird repellent.

Methyl benzoate

Methyl benzoate is the benzoate ester of benzoic acid and methanol, a colorless liquid with a sweet, balsamic, spicy floral odor, found naturally in flowers and fruits.

Methyl beta-cyclodextrin

Methyl beta-cyclodextrin (MβCD) is a methylated, water-soluble derivative of beta-cyclodextrin, a cyclic seven-glucose sugar. It is the standard reagent for depleting cholesterol from cell membranes and a solubilizing excipient in drugs.

Methyl bromide

Methyl bromide, also known as bromomethane, is an odorless gas long used to fumigate soil and shipments against pests, phased out by 2005 for depleting ozone.

Methyl butyrate

Methyl butyrate, also known as methyl butanoate, is the methyl ester of butyric acid, a volatile liquid with a fruity apple and pineapple odor used in flavorings.

Methyl cellulose

Methyl cellulose (Citrucel) is a cellulose ether that dissolves in cold water and gels when heated, used as a food thickener, drug excipient, and mortar additive.

Methyl chloride

Methyl chloride, also called chloromethane (CH₃Cl), is a colorless, toxic, flammable gas and the most prevalent organochlorine compound in the atmosphere, produced mostly by natural sources like oceans and biomass burning.

Methyl cinnamate

Methyl cinnamate is the methyl ester of cinnamic acid, a white crystalline solid with formula C10H10O2 and a strawberry-like, balsamic odor used as a flavoring and fragrance.