All articles starting with P
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Peggy Wood
Peggy Wood (Mary Margaret Wood, 1892–1978), American stage, film, and television actress and singer; star of CBS's Mama (1949–1957) and Oscar-nominated Mother Abbess in The Sound of Music (1965); ANTA president 1959–1966.
Peggys Cove, Nova Scotia
Peggys Cove, Nova Scotia: a fishing village on St. Margaret's Bay, home of Peggy's Point Lighthouse. Founded by an 1811 land grant to six German-descent families; famous granite coast, tourism icon, hazardous waves.
Pegi Young
Pegi Young (born Margaret Mary Young, 1952) was an American singer-songwriter who co-founded the Bridge School for children with severe impairments and released five solo albums.
Pegida
Pegida (Patriotische Europäer gegen die Islamisierung des Abendlandes) is a right-wing populist, anti-immigration protest movement founded by Lutz Bachmann in Dresden in October 2014, known for Monday marches peaking at about 25,000 in January 2015 and close ties to the AfD.
Pegilodecakin
Pegilodecakin, known by the development codes AM0010 and LY3500518, is a PEGylated interleukin-10 drug investigated as a cancer immunotherapy that reached phase 3 testing but was never approved.
Peginesatide
Peginesatide (Omontys), a once-monthly peptide-based erythropoiesis-stimulating agent for anemia in dialysis patients, was FDA-approved in 2012 and recalled in February 2013 after fatal anaphylaxis reactions.
Peginterferon alfa-2a
Peginterferon alfa-2a (Pegasys, PEG-IFN alfa-2a) is a PEGylated recombinant interferon alfa-2a approved in 2002 for chronic hepatitis B and C and later for polycythaemia vera and essential thrombocythaemia, given weekly by subcutaneous injection.
Peginterferon alfa-2b
Peginterferon alfa-2b (PegIntron, Sylatron) is a 12 kDa linear PEG conjugate of interferon alfa-2b, once-weekly injected for chronic hepatitis C and melanoma; EU marketing withdrawn in 2021.
Peginterferon alfa-2b, Y-shaped 40 kDa (Pegbing)
Pegbing (派格宾) is Xiamen Amoytop's 40 kDa Y-shaped pegylated interferon alfa-2b, China's first domestically developed long-acting interferon, approved 2016; 180 μg weekly; non-inferior to peginterferon alfa-2a in HBeAg-positive hepatitis B.
Peginterferon beta-1a
Peginterferon beta-1a (Plegridy, Biogen) is a 20 kDa PEG-conjugated interferon beta-1a for relapsing-remitting multiple sclerosis, given 125 mcg subcutaneously every 2 weeks; FDA and EU approved in 2014.
Peginterferon lambda-1a
Peginterferon lambda-1a (Lambda, PEG-IFN-λ1a) is a pegylated type III interferon developed at ZymoGenetics for chronic hepatitis C; better tolerated than alfa interferons but failed Phase 3 noninferiority and showed no COVID-19 benefit.
Pegloticase
Pegloticase, marketed as Krystexxa, is a PEGylated uricase enzyme given by intravenous infusion every two weeks to lower urate in adults with gout refractory to oral therapy.
Pegmatite
Pegmatite is a coarse-grained igneous rock composed largely of granite minerals such as quartz, feldspar, and muscovite, mined for rare elements like lithium and tantalum, and for gemstones.
Pegmolesatide
Pegmolesatide (培莫沙肽, Saint Luolai) is Hansoh Pharma's once-monthly PEGylated erythropoietin-mimetic peptide for renal anemia, approved by China's NMPA in June 2023 and non-inferior to epoetin alfa in phase 3 trials.
Pegnesischer Blumenorden
The Pegnesischer Blumenorden, or Pegnesian Flower Order, is a literary and language society founded in Nuremberg in 1644 that cultivates German poetry, the only Baroque-era German language society still existing.
Pegnivacogin
Pegnivacogin (RB006, Revolixys, DTRI-178) is a PEGylated 31-mer RNA aptamer inhibiting factor IXa, paired with the antidote anivamersen in the REG1 anticoagulation system; halted in phase 3 after allergic reactions.
Pegozafermin
Pegozafermin (BIO89-100), a glycoPEGylated FGF21 analog by 89bio, now Roche, treats MASH and severe hypertriglyceridemia; ENLIVEN phase 2b showed fibrosis improvement and NASH resolution.
Pegtibatinase
Pegtibatinase (OT-58, TVT-058) is a PEGylated truncated human cystathionine beta-synthase enzyme replacement therapy for classical homocystinuria, in Phase 3 (HARMONY) by Travere Therapeutics, cutting plasma total homocysteine about 67% in COMPOSE.
Pegunigalsidase alfa
Pegunigalsidase alfa (Elfabrio, pegunigalsidase alfa-iwxj) is a PEGylated recombinant alpha-galactosidase A enzyme replacement therapy made in tobacco cells, approved in 2023 for adults with Fabry disease, dosed 1 mg/kg IV every 2 weeks, noninferior to agalsidase beta in the BALANCE trial.
Pegunungan Arfak
Pegunungan Arfak (Arfak Mountains), a range on the Bird's Head Peninsula, West Papua, Indonesia; highest peak Gunung Mebo 2,955 m; 68,325 ha nature reserve designated 1982; birdwatching tourism.
Pegunungan Cycloop
Pegunungan Cycloop, also called the Cyclops Mountains, is a mountain range on the north coast of Jayapura, Papua Province, Indonesia, stretching about 40 km west to east.
Pegunungan Gauttier
Pegunungan Gauttier (Gauttier Mountains, Foja Mountains) is a mountain range in northern Papua, Indonesia, in Sarmi Regency; highest peak 2,230 m with 2,007 m prominence, separated from the Van Rees Mountains by the Mamberamo River.
Pegunungan Kobowre
Pegunungan Kobowre, also known as the Kobowre Mountains or Weyland Mountains, is a mountain range in western New Guinea's Central Range, with altitudes up to 3,891 m.
Pegunungan Pompangeo
Pegunungan Pompangeo (Pompangeo Mountains, Pompangeo Gebergte) is a mountain range in Central Sulawesi, Indonesia, 2,278 m high, forming the boundary between Poso and North Morowali regencies and built of the Early Cretaceous Pompangeo Schist Complex.
Pegunungan Wondiwoi
Pegunungan Wondiwoi, or Wondiwoi Mountains, is a mountain range on the Wandammen Peninsula in West Papua, Indonesia, home to the critically endangered Wondiwoi tree kangaroo.
Pegvaliase
Pegvaliase (Palynziq, pegvaliase-pqpz) is a PEGylated bacterial phenylalanine ammonia lyase injected subcutaneously for phenylketonuria with Phe >600 micromol/L; FDA approved 2018, EU 2019, extended to ages 12+ in 2026.
Pegvisomant
Pegvisomant (Somavert) is a PEGylated growth hormone receptor antagonist approved in 2003 for acromegaly uncontrolled by surgery or radiation; daily subcutaneous injection normalizing IGF-1, with real-world control around 62–71%.
PEGylated nanographene
PEGylated nanographene is nanoscale graphene oxide grafted with polyethylene glycol, giving water solubility, longer blood circulation, and passive tumor targeting; it remains limited to preclinical cancer drug delivery research.
PEGylation
PEGylation, also called PEG labeling, is the covalent attachment of polyethylene glycol chains to therapeutic molecules such as proteins to prolong their circulation half-life, first FDA-approved in 1990.
Pegzilarginase
Pegzilarginase (Loargys, pegzilarginase-nbln) is a pegylated recombinant human arginase 1 enzyme, dosed weekly IV or subcutaneously, that lowers plasma arginine in arginase 1 deficiency (hyperargininemia); EU-approved 2023, FDA accelerated approval 2026.