All articles starting with P
28,818 articles
Pihhuniya
Pihhuniya (Piḫḫuniya) was a Kaska chieftain of Tipiya in northern Anatolia who attacked the Hittite Upper Land and was captured by Mursili II, who said he ruled "in the manner of a king".
PiHKAL
PiHKAL: A Chemical Love Story is a 1991 book by chemist Alexander Shulgin and Ann Shulgin, combining a fictionalized autobiography with a reference on 179 phenethylamines.
Pihkva
Pihkva, also called Lake Pskov (Russian: Псковское озеро), is the southernmost, shallowest basin of the Lake Peipsi system, a 708 km² lake on the Estonia–Russia border.
PIHRK'D trial
PIHRK'D (NCT06080425) is a completed ADA-funded feasibility trial by UTMB Galveston testing family-based medical nutrition therapy and Dining with Diabetes for 48 rural Kentuckians with type 2 diabetes and overweight or obesity.
Pihu
Pihu is a 2018 Hindi-language Indian drama thriller written and directed by Vinod Kapri, starring two-year-old Myra Vishwakarma as a toddler trapped alone with her dead mother; released 16 November 2018.
PII A trial
The PII A trial, known as PARTNER 2A, was a randomized trial comparing transcatheter (TAVR) with surgical aortic valve replacement in 2,032 intermediate-risk patients with severe aortic stenosis.
Pijin language
Pijin (Solomon Islands Pidgin, Neo-Solomonic, Tok Pijin) is the English-lexified lingua franca of Solomon Islands, related to Tok Pisin and Bislama; at least 420,000 speakers, nativizing in Honiara, unstandardised orthography.
Pijush Hazarika
Pijush Hazarika is an Indian BJP politician and Assam minister holding the Parliamentary Affairs, Agriculture, and Irrigation portfolios, representing Jagiroad in the Assam Legislative Assembly.
Pik Aborigen
Pik Aborigen (Пик Абориген), summit in the Bolshoy Anngachak range, Chersky system, Magadan Oblast, Russia; long cited at 2,586 m, revised to about 2,286-2,287 m; first climbed 1957 by P. Z. Demant; regional nature monument since 2017.
Pik Achiktash (ex. Lenina)
Pik Achiktash (ex. Lenina): entry name for Lenin Peak, now Ibn Sina Peak (пик Ленина), a 7,134 m Pamir summit on the Kyrgyzstan–Tajikistan border, with the Achiktash valley base camp at 3,600 m.
Pik BAM (HP Kodar)
Pik BAM (Пик БАМ), 3,072 m, is the highest peak of the Kodar Ridge and of Zabaykalsky Krai, Transbaikalia, Siberia; first climbed 26 July 1963 by Chita alpinists led by A. I. Kuzminykh and named for the Baikal-Amur Mainline builders.
Pik Botha
Roelof Frederik "Pik" Botha (1932–2018), South African diplomat and National Party politician, foreign minister 1977–1994 under apartheid and later Mandela's mines and energy minister; key figure in nuclear diplomacy.
Pik Imeni Ismail Samani (ex. Kommunizma)
Pik Imeni Ismail Samani (Ismoil Somoni Peak, ex-Stalin Peak, ex-Communism Peak) is Tajikistan's 7,495 m highest summit in the Pamirs' Academy of Sciences Range, first climbed in 1933 by Yevgeniy Abalakov.
Pik Karla Marksa
Pik Karla Marksa, also called Karl Marx Peak (Пик Карла Маркса), is a 6,723-meter glaciated mountain in the Shakhdara Range of the Pamir in Tajikistan.
Pik Mus-Khaya
Pik Mus-Khaya (Мус-Хая, Муус Хайа, "Ice mountain") is a 2,959 m ultra-prominent peak in Yakutia, Russia, highest summit of the Suntar-Khayata Range, second highest in Yakutia, with Northeast Siberia's largest glaciated area.
Pik Patkhor
Pik Patkhor (Патхор, Patkhor Peak) is a 6,083 m mountain in Gorno-Badakhshan, Tajikistan, the highest summit of the Rushan Range in the Pamirs, first climbed in 1946.
Pik Revolutsii
Pik Revolutsii (Revolution Peak), now officially Qullai Istiqlol, is a 6,940 m peak in the Yazgulem Range of the central Pamir, Tajikistan, first climbed in 1954.
Pik Sat
Pik Sat is a mountain peak located in the Pamir region of Tajikistan, near the Trans-Alay range border. This peak is considered ultra-prominent as its topographic prominence surpasses 1,500 meters.
Pik Skalistiy
Pik Skalistiy (Пик Скалистый), a 5,621 m ultra-prominent peak in the Turkestan Range, Batken, Kyrgyzstan; highest point of the Central Turkestan Ranges; distinct from same-named peaks in Tajikistan, Almaty, and the Caucasus.
Pik Sovetskikh Ofitserov (HP Muzkol)
Pik Sovetskikh Ofitserov (пик Советских Офицеров), 6,233 m, is the highest peak of the Muzkol Range in the Eastern Pamir, Tajikistan; an Ultra with 1,980 m prominence, named in 1945 and first climbed in 1988.
Pik Talgar
Pik Talgar (Пик Талгар), highest peak of the Zailiyskiy Alatau in Kazakhstan's Tian Shan, elevation 4,978.9–5,017 m depending on source; first climbed 1938, with glaciers feeding the Talgar River.
Pik-Sen Lim
Pik-Sen Lim (Lim Phaik-Seng, 1944–2025), Malaysian-born British actress of Mind Your Language, Doctor Who, Johnny English Reborn, and narrator of Dark Souls and Dark Souls III; died June 9, 2025.
PIK3C3
PIK3C3 (VPS34) is the sole class III phosphatidylinositol 3-kinase gene in humans, encoding an 887-aa lipid kinase that makes PI3P for autophagy, endosomal trafficking, and cardiovascular and immune cell function.
PIK3CA
PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) encodes p110α of PI3Kα on chromosome 3; hotspot-mutated in over 30% of breast cancers, a biomarker for PI3K/AKT inhibitor therapy, and causative of PROS overgrowth disorders.
PIK3CB
PIK3CB (p110beta) is a human gene at 3q22.3 encoding the beta catalytic subunit of class IA phosphoinositide 3-kinase, a ubiquitous lipid kinase activated by both RTKs and GPCRs, central to PTEN-deficient tumors and thrombosis, and targeted by inhibitors such as TGX-221 and AZD8186.
PIK3CD
PIK3CD encodes p110δ, the leukocyte-restricted catalytic subunit of PI3Kδ. Gain-of-function variants cause APDS1 (~75% of cases, hotspot E1021K); the gene is targeted by PI3Kδ inhibitors including leniolisib (Joenja), the first approved APDS drug (US, March 2023).
PIK3CG
PIK3CG encodes p110γ, the catalytic subunit of class IB PI3Kγ, a GPCR- and Ras-activated lipid kinase on chromosome 7q22.3, key to leukocyte signaling, IPGS immunodeficiency when lost, and a cancer drug target.
PIK3R1
PIK3R1 (p85alpha, GRB1, IMD36) is a gene at 5q13.1 encoding the p85α regulatory subunit of PI3K; germline mutations cause APDS2 immunodeficiency and SHORT syndrome, somatic mutations drive endometrial and other cancers.
PIK3R2
PIK3R2 (p85beta, MPPH1) is a chromosome 19 gene encoding the p85beta regulatory subunit of PI3K. Gain-of-function variants cause MPPH syndrome (megalencephaly, polymicrogyria, polydactyly, hydrocephalus); overexpression acts as an oncogene in melanoma, breast, and lung cancer.
Pika
Pika (Ochotona), family Ochotonidae, order Lagomorpha: small tailless, short-eared mammals of cold Asian and North American mountains; ~30 species, four subgenera; American pika O. princeps builds haystacks and is heat-sensitive above 25.5 degrees C.