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All articles starting with P

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PSJ Cobre Mendocino

PSJ Cobre Mendocino, formerly the San Jorge project, is a copper-gold porphyry mining project in Uspallata, Mendoza Province, Argentina, developed by Minera San Jorge S.A.

Pskov

Pskov (Псков), ancient Russian city and administrative center of Pskov Oblast on the Velikaya River; first recorded in 903, a medieval veche republic and fortress, home of the Pskov School of Architecture inscribed by UNESCO in 2019.

Pskov Judicial Charter

The Pskov Judicial Charter (Псковская судная грамота) is the law code of the Pskov republic, compiled in the 14th or 15th century in 120 articles.

Pskov Oblast

Pskov Oblast (Псковская область), a Russian federal subject formed 23 August 1944 with center Pskov; the only Russian region bordering Estonia, Latvia, and Belarus; 55.3 thousand km², population 613,356 (2022).

Pskov Republic

The Pskov Republic (Псковская республика) was a Russian city-state centered on Pskov that governed itself through a popular assembly, or veche, until its incorporation into the Russian state.

Pskov school of icon painting

The Pskov school of icon painting (Псковская школа иконописи) was a regional school of Old Russian art, active in Pskov from the 13th to 16th centuries.

Pskov standoff and double suicide

Pskov standoff and double suicide: Denis Muravyov and Katya Vlasova, two 15-year-olds from Pskov, Russia, barricaded themselves in Strugi Krasnye on 14 November 2016, livestreamed firing at police on Periscope, and were found dead before the SOBR entry.

Pskov's independence from Novgorod (Bolotovo Treaty, 1348)

The Bolotovo Treaty, concluded at Bolotovo in 1348 between the Novgorod Republic and the Pskov community, recognized Pskov's independence in appointments, courts, and church administration, formalizing long-standing practice.

PSKW

PSKW was a Bedminster, New Jersey provider of co-pay offset cards, vouchers, and pharmacy claim adjudication sold to drug makers, serving over 300 brand teams before merging into ConnectiveRx by 2017.

PSL (rifle)

The PSL (Pușca Semiautomată cu Lunetă) is a Romanian designated marksman rifle adopted in 1974, chambered in 7.62×54mmR and resembling the SVD Dragunov though built on a Kalashnikov-pattern action.

PSLV

The Polar Satellite Launch Vehicle (PSLV) is a four-stage Indian rocket operated by ISRO since 1993, nicknamed the Workhorse of ISRO. In 2017 it launched 104 satellites in one flight.

PSM Makassar

PSM Makassar (Persatuan Sepakbola Makassar, Juku Eja), founded 2 November 1915 as MVB, Indonesia's oldest active football club; seven league titles including Liga 1 2022/23, based at Gelora BJ Habibie, Parepare.

PSMA PET

PSMA PET is a nuclear medicine imaging method that detects and stages prostate cancer using radiotracers binding prostate-specific membrane antigen, standard of care since 2020.

PSMA6

PSMA6 (proteasome 20S subunit alpha 6, alpha-1/IOTA) is a human gene at 14q13.2 encoding a 246-aa alpha-ring subunit of the 20S proteasome; linked to CAD risk variant rs1048990 and proposed as a lung cancer target. Not the prostate PSMA antigen.

PSMB1

PSMB1 encodes beta-6, a non-catalytic structural subunit of the human 20S proteasome core. Biallelic Tyr103His variants cause recessive microcephaly and intellectual disability; high expression marks unfavorable prognosis in breast, liver, lung, and urothelial cancers.

PSMB10

PSMB10 (MECL-1, LMP10, beta2i) encodes the IFN-gamma-inducible trypsin-like catalytic subunit of the immunoproteasome at 16q22.1, replacing constitutive beta2 and supporting MHC class I antigen presentation.

PSMB2

PSMB2 (proteasome 20S subunit beta 2) encodes a non-catalytic beta subunit of the human 20S proteasome core, 201 amino acids, mapped to 1p34.2, incorporated early during proteasome assembly and used for FLAG-tag proteasome purification.

PSMB4

PSMB4 (proteasome 20S subunit beta 4, HsN3/PROS-26) is a human gene at 1q21.3 encoding the non-catalytic β7 subunit of the 20S proteasome, rate-limiting for assembly; biallelic mutations cause PRAAS3/CANDLE autoinflammation.

PSMB8

PSMB8 (LMP7, β5i) is a human chromosome 6 gene encoding the inducible immunoproteasome subunit beta 8; autosomal recessive mutations cause PRAAS, including Nakajo-Nishimura, JMP, and CANDLE syndromes.

PSMB9

PSMB9 (LMP2, β1i) is the human gene for an immunoproteasome catalytic subunit at 6p21.3 in the MHC class II region; IFN-γ-induced, it replaces β1 to generate hydrophobic C-terminal peptides for MHC class I presentation, with SNPs linked to multiple sclerosis risk and a p.G156D variant causing neonatal autoinflammation.

PSMD1

PSMD1 (S1, P112, Rpn2), gene ID 5707 on human chromosome 2, encodes the largest non-ATPase lid subunit of the 19S proteasome regulator; overexpressed in HCC, myeloma, and CML, a prognostic marker and emerging siRNA target.

PSMD14

PSMD14, also called Rpn11 or POH1, is the essential zinc-dependent JAMM metalloprotease deubiquitinase of the 19S proteasome lid that removes whole polyubiquitin chains en bloc, coupling deubiquitination to ATP-dependent substrate degradation, and is an emerging cancer drug target.

PSMD2

PSMD2 (Rpn1, 26S proteasome non-ATPase regulatory subunit 2) is a 19S base scaffold and ubiquitin/UBL-binding subunit of the 26S proteasome, overexpressed in lung, breast, esophageal, bladder, pancreatic, and liver cancers and a candidate therapeutic target.

PSMD4

PSMD4 (Rpn10, S5a) is the 377-aa intrinsic ubiquitin receptor of the 26S proteasome's 19S regulatory particle, with a VWA domain and two UIMs binding K48/K63 polyubiquitin; embryonic lethal in mice and implicated in myeloma and liver cancer.

PSMPD trial

PSMPD trial (NCT05239065), Personalized Stress Management With Application of Portable Devices in Occupational Populations: nonrandomized controlled study in two Wuhan hospitals testing Huawei-device-supported stress coaching for 245 healthcare workers; PSS improved, HRV did not differ.

Psoas major muscle

Psoas major: deep core muscle joining the iliacus as the iliopsoas, the thigh's primary flexor; inserts separately on the lesser trochanter and crosses the ~3 o'clock psoas valley of the acetabular rim.

Psocidae

Psocidae, the common barklice, is the largest family of free-living barklice (Psocodea: Psocomorpha: Psocetae), with over 1,000 species in about 80 genera, mostly tropical, classified in three subfamilies and ten tribes.

Psocodea

Psocodea is an insect order uniting bark lice, book lice, and parasitic lice (former orders Psocoptera and Phthiraptera, now synonyms), with over 11,000 species, seven suborders, and a single origin of parasitism predating the K-Pg boundary.

Psophia

Psophia is a genus of Amazonian ground-dwelling birds known as trumpeters, the only genus of the family Psophiidae in the order Gruiformes, established by Linnaeus in 1758.

Psophocarpus

Psophocarpus, a small African-Madagascan legume genus in Fabaceae tribe Phaseoleae, is known for the winged bean P. tetragonolobus, a protein-rich multipurpose tropical crop with four-winged, explosively dehiscent pods.