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All articles starting with S

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Spindle (textiles)

Spindle (textiles): a shaft with a whorl for hand-spinning fiber into yarn; drop and supported types; used since the Neolithic, replaced by the spinning wheel in the late Middle Ages.

Spindle and kinetochore-associated protein 1

SKA1 (C18orf24), spindle and kinetochore-associated complex subunit 1, is a 255-amino-acid human protein of the SKA1-SKA2-SKA3 complex that stabilizes kinetochore-microtubule attachments in mitosis and, when overexpressed, drives metastasis and cisplatin resistance in lung and other cancers.

Spindle apparatus

Spindle apparatus (mitotic spindle): microtubule structure of cell division with two spindle poles and astral, polar, and kinetochore microtubules; segregates chromosomes, targeted by taxanes and vinca alkaloids.

Spindle assembly checkpoint component Mad1

Mad1 (MAD1L1), mitotic arrest deficient 1, is a coiled-coil spindle assembly checkpoint scaffold that recruits Mad2 to unattached kinetochores as a 2:2 MAD1:C-MAD2 tetramer catalyzing Mad2's open-to-closed conversion; MPS1-regulated, also recruits CENP-E, and dosage changes cause aneuploidy and cancer.

Spindle cell hemangioma

Spindle cell hemangioma, also called spindle cell hemangioendothelioma, is a rare benign vascular tumor of the dermis and subcutis with IDH1/IDH2 mutations, painful limb nodules, frequent local recurrence, and no metastatic potential.

Spindle orientation and cleavage-plane specification

Spindle orientation and cleavage-plane specification: how dividing cells position the mitotic spindle via astral microtubules, cortical dynein, and the conserved Gαi–LGN–NuMA complex to set the cleavage plane, daughter-cell size, and fate.

Spindle-shaped archaeal viruses

Spindle-shaped archaeal viruses are viruses of archaea with lemon- or spindle-shaped virions, a morphotype exclusive to the Archaea, infecting hosts from hot springs to salt lakes.

SpindleHorse

SpindleHorse (SpindleHorse Toons) is the independent, women-led Burbank, California animation studio founded in 2018 by Vivienne Medrano (VivziePop), producer of Hazbin Hotel and Helluva Boss, unionized with IATSE in 2025.

Spindletop

Spindletop, an oil field south of Beaumont, Texas, marked the birth of the modern petroleum industry when the Lucas Gusher blew in on January 10, 1901.

Spindrift Beverage Co.

Spindrift Beverage Co. is an American beverage company in Newton, Massachusetts, founded by Bill Creelman in 2010, known for sparkling water made with real squeezed fruit.

Spine (video game)

SPINE (SPINE - This is Gun Fu) is an upcoming single-player cyberpunk gun-fu action game by Nekki, starring Redline and her sentient implant in Tensor City, launching Summer 2027 on PC, PS5, and Xbox Series X|S.

Spine deformity

Spine deformity, including scoliosis and adult spinal deformity, is an abnormal spinal curvature measured by the Cobb angle; prevalence reaches 68% over age 60, managed nonoperatively or by fusion.

Spinel

Spinel, also known as Balas ruby, is a magnesium aluminum oxide gem mineral, historically mistaken for ruby; famous "rubies" in the English Crown Jewels are spinel.

Spinetoram

Spinetoram (DIANA), a semisynthetic spinosyn insecticide from Saccharopolyspora spinosa, major component 3′-O-ethyl-5,6-dihydro spinosyn J; launched 2007, Green Chemistry Award 2008, EU approval expired 2024.

SPINK1

SPINK1 (serine peptidase inhibitor Kazal type 1; PSTI, TATI) is a 56-amino-acid trypsin inhibitor secreted by pancreatic acinar cells; loss-of-function variants, notably N34S, raise pancreatitis risk tenfold to 40-fold heterozygously.

SPINK5

SPINK5 (serine peptidase inhibitor Kazal type 5), also called LEKTI/NETS, is a gene on 5q32 encoding a 15-domain serine protease inhibitor; biallelic mutations cause Netherton syndrome, and it acts as a tumor suppressor in oral squamous cell carcinoma.

Spinka (שפינקא) (Hasidic dynasty)

Spinka (שפינקא) is a Hasidic dynasty founded by Rabbi Yosef Meir Weiss in 1876 in Spinka, Maramureș, now Romania, and continued today by dozens of rebbes in the United States and Israel.

SpinLaunch

SpinLaunch is a California-based space company founded in 2014 that uses a large electric centrifuge in a vacuum chamber to launch projectiles, with suborbital test flights from Spaceport America in New Mexico since 2021.

Spinlock

A spinlock is a mutual exclusion lock where a waiting thread busy-waits by repeatedly checking the lock, efficient for critical sections shorter than a context switch.

Spinnaker

A spinnaker is a large, light, three-cornered downwind sail set flying from the masthead on a sailing yacht, in symmetric and asymmetric types, first recorded in 1866.

Spinner (robot)

Spinner is an unmanned ground combat vehicle prototype developed for DARPA by Carnegie Mellon University's NREC with Boeing, known for driving while upside down and serving as the base for its successor, Crusher.

Spinning (textiles)

Spinning, also known as hand spinning or wool spinning, is the textile process of converting staple fiber into yarn by drawing and twisting it; ring spinning has dominated since the early 1800s.

Spinning bee

Spinning bee: a communal gathering where women spin yarn together. Known from early modern Europe (Spinnstube, veillée) and colonial New England, where 1766–1771 bees produced homespun as protest against British imports.

Spinning disk confocal microscopy

Spinning disk confocal microscopy (SDCM) is a fluorescence technique that forms optical sections through a rotating disk of pinholes, enabling fast, low-phototoxicity 3D imaging of living cells.

Spinning Gears

Spinning Gears (歯車, Haguruma) is a short story by the Japanese writer Akutagawa Ryūnosuke, written in 1927 and published posthumously in Bungei Shunjū, describing a writer's breakdown through visions of translucent gears.

Spinning jenny

The spinning jenny is a hand-powered multi-spindle spinning machine invented in the 1760s by the Lancashire weaver James Hargreaves, letting one operator spin eight threads at once.

Spinning Man

Spinning Man: 2018 psychological thriller by Swedish director Simon Kaijser, screenplay Matthew Aldrich, adapted from George Harrar's 2003 novel. Guy Pearce plays philosophy professor Evan Birch, prime suspect in a student's disappearance, opposite Pierce Brosnan's Detective Malloy; Lionsgate Premiere released it to $283,755 and mixed reviews.

Spinning Out

Spinning Out is a 2020 Netflix drama series, 10 episodes, created by former skater Samantha Stratton, starring Kaya Scodelario as injured skater Kat Baker; canceled after one season.

Spinning reserve

Spinning reserve is the portion of operating reserve from generators already synchronized to the grid and running below full output, able to increase production within about 10 minutes.

Spinning Up in Deep RL

Spinning Up in Deep RL is an educational resource released by OpenAI in 2018, combining RL theory, a reading list, and minimal implementations of six core algorithms.