All articles starting with S
44,216 articles
Squamous cell carcinoma of cornea
Squamous cell carcinoma of the cornea is a rare invasive cancer of the corneal surface epithelium, the advanced end of a spectrum called ocular surface squamous neoplasia.
Squamous cell carcinoma of floor of mouth
Squamous cell carcinoma of the floor of mouth (FOM SCC) is a malignancy beneath the tongue, about 10% of oral SCCs. High occult nodal spread (21% stage I), surgery mainstay, 5-year survival 95% to 52% by stage.
Squamous cell carcinoma of middle ear
Squamous cell carcinoma of middle ear (ICD-11 2C21.1), a rare keratinising carcinoma of middle ear epithelium; presents as otorrhea, otalgia, hearing loss; treated by temporal bone resection plus radiotherapy.
Squamous cell carcinoma of nasal cavity
Squamous cell carcinoma of the nasal cavity (NCSCC), also sinonasal SCC, is the most common sinonasal malignancy, linked to wood dust and other occupational carcinogens and partly to HPV; treated by surgery plus adjuvant radiotherapy, with about 50-55% five-year survival.
Squamous cell carcinoma of nasopharynx
Squamous cell carcinoma of nasopharynx (ICD-11 2B6B.0), also called nasopharyngeal carcinoma (NPC), is a malignant mucosal epithelial tumor of the nasopharynx with squamous differentiation; WHO subtypes keratinizing, non-keratinizing, basaloid; strongly EBV-linked, radiotherapy-treated.
Squamous cell carcinoma of palate
Squamous cell carcinoma of the palate (ICD-11 2B65.1) is SCC of the hard or soft palate. Hard palate SCC is about 2% of head and neck SCC; surgery is the mainstay; soft palate invasion worsens survival.
Squamous cell carcinoma of parotid gland
Squamous cell carcinoma of the parotid gland, primary parotid SCC, is a rare aggressive salivary malignancy; about 90% of parotid SCC is metastatic from cutaneous or mucosal head and neck primaries, making primary disease a diagnosis of exclusion.
Squamous cell carcinoma of scrotum
Squamous cell carcinoma of the scrotum (scrotal SCC, chimney sweep's cancer) is a rare male genital skin cancer, about 35% of scrotal malignancies, first linked to soot by Pott in 1775; 5-year relative survival is 77%.
Squamous cell carcinoma of skin
Squamous cell carcinoma of the skin (cutaneous squamous cell carcinoma, cSCC) is a cancer of epidermal squamous cells, usually sun-induced; second most common skin cancer after basal cell carcinoma, treated first with surgery and with anti-PD-1 immunotherapy when advanced.
Squamous cell carcinoma of the anal canal
Squamous cell carcinoma of the anal canal (SCCA), also called epidermoid anal cancer, is the most common anal cancer, 95% HPV-related (types 16, 18). Treated since the 1974 Nigro protocol with sphincter-preserving 5-FU/mitomycin chemoradiation; surgery is salvage.
Squamous cell carcinoma of the base of the tongue
Squamous cell carcinoma of the base of the tongue (ICD-11 2B6I.0) is an oropharyngeal cancer of the posterior tongue third, strongly linked to HPV16, often neck-node positive at diagnosis, treated with transoral surgery or chemoradiation, with better survival when HPV-positive.
Squamous cell carcinoma of the cervix uteri
Squamous cell carcinoma of the cervix uteri, also called cervical squamous cell carcinoma or epidermoid carcinoma (ICD-O 80703), is the most common cervical cancer type, arising from HPV-driven transformation of ectocervical squamous cells at the transformation zone.
Squamous cell carcinoma of the colon
Squamous cell carcinoma of the colon (colorectal SCC, ORPHA:423994) is an extremely rare colonic squamous-cell cancer, 0.1-0.25 per 1,000 colorectal carcinomas, diagnosed by excluding anal extension, fistulas, and metastasis, with worse survival than rectal SCC.
Squamous cell carcinoma of the corpus uteri
Squamous cell carcinoma of the corpus uteri (endometrial squamous cell carcinoma, ICD-O 8070/3) is a rare uterine cancer, under 0.5% of endometrial carcinomas, affecting postmenopausal women with discharge, bleeding, pain, often with cervical stenosis and pyometra.
Squamous cell carcinoma of the esophagus
Squamous cell carcinoma of the esophagus is a cancer of the flat cells lining the esophagus, causing about 85 to 90 percent of esophageal cancers worldwide.
Squamous cell carcinoma of the lip
Squamous cell carcinoma of the lip (lip SCC), a head and neck cancer usually arising at the lower-lip vermilion border; over 25% of oral cancers, mainly older white men, treated mostly by surgery, with 9% mean occult metastasis rate.
Squamous cell carcinoma of the oral cavity
Squamous cell carcinoma of the oral cavity (OSCC, oral cavity SCC), the most common oral malignancy; tobacco, alcohol, and betel quid are main risk factors; treated mainly by surgery with neck dissection and adjuvant radiotherapy.
Squamous cell carcinoma of the penis
Squamous cell carcinoma of the penis (PSCC) is the dominant penile malignancy, over 95% of cases, arising from glans or inner prepuce epithelium; about 40% are HPV-associated (mainly HPV 16), classified by the 2022 WHO as HPV-associated or HPV-independent, with survival strongly tied to nodal status.
Squamous cell carcinoma of the rectum
Squamous cell carcinoma of the rectum (rectal SCC, rSCC) is a rare squamous-differentiated rectal cancer, under 1% of rectal tumors, defined by the Williams criteria, treated mainly with definitive chemoradiation, with worse survival than anal SCC.
Squamous cell carcinoma of the small intestine
Squamous cell carcinoma of the small intestine (SCC-SI), an extremely rare malignant epithelial tumor, usually duodenal; roughly 27 primary cases reported, arising via metaplasia or ectopic epithelium, with median survival about six months.
Squamous cell carcinoma of the stomach
Squamous cell carcinoma of the stomach, also called primary gastric squamous cell carcinoma, is a very rare stomach cancer, accounting for under 0.5 percent of cases.
Squamous cell carcinoma of tonsil
Tonsillar squamous cell carcinoma (TSCC), tonsil cancer: oropharyngeal SCC, about half HPV-16 positive, 71-89% nodal spread, treated with radiotherapy, transoral surgery, or chemoradiation; HPV-positive disease has better survival.
Squamous cell carcinoma of trachea
Squamous cell carcinoma of trachea (ICD-11 2C24.1), the most common primary tracheal cancer; smoking-related, male-predominant, aggressive; 5-year overall survival about 25%, better with curative surgery or chemoradiation.
Squamous cell carcinoma of urinary bladder
Squamous cell carcinoma of urinary bladder (ICD-11 2C94.1), a keratin-forming bladder cancer from metaplastic epithelium; 2–5% of Western bladder tumors, schistosomiasis-linked in endemic regions, treated by radical cystectomy.
Squamous cell carcinoma of vagina
Squamous cell carcinoma of vagina (ICD-11 2C71.2; ICD-10 C52) is the most common vaginal cancer, about 80-90% of cases, usually HPV-driven, treated mainly with surgery or radiation.
Squamous-cell carcinoma
Squamous-cell carcinoma (SCC, epidermoid carcinoma) is cancer of squamous cells in skin and organ linings; cutaneous SCC is the second most common skin cancer, cured in over 90% of early cases, treated by excision or anti-PD-1 immunotherapy when advanced.
Squanto
Squanto (Tisquantum), Patuxet Wampanoag interpreter and guide for Plymouth Colony, kidnapped in 1614, sole survivor of his village, died 1622 at Manamoick.
Square
A square, also called a regular quadrilateral, is a plane figure with four equal sides and four right angles, its area being the side length squared.
Square (algebra)
In algebra, the square of a number or expression is the result of multiplying it by itself, written x², so named because a square's area is its side squared.
Square (video game company)
Square Co., Ltd., also known as SquareSoft, was a Japanese video game developer founded in September 1986, best known for the Final Fantasy series and its merger with Enix.