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Spoletium
Spoletium (Spoleto, Umbria): Iron Age hill settlement, Latin colony from 241 BC, municipium on the via Flaminia, home of the Lex luci spoletina, and Lombard duchy from CE 570.
Spoliarium
Spoliarium, 1884 oil on canvas by Juan Luna (4.22 × 7.675 m), gold medal at the 1884 Madrid Exposición Nacional; fallen gladiators allegory of colonial Philippines; largest Philippine painting, National Museum of Fine Arts, Manila.
Spoligotyping
Spoligotyping (spacer oligonucleotide typing) is a PCR-based method that reads DR-region spacer sequences to identify and differentiate tuberculosis strains, delivering results in one to three days.
Spolok svätého Vojtecha
Spolok svätého Vojtecha (Society of Saint Adalbert, SSV) is the largest and oldest Catholic association in Slovakia, founded in 1870 in Trnava by Andrej Radlinský.
Spolverino, Alberese
Spolverino (Alberese, Grosseto, Tuscany) is a Roman archaeological site on the Ombrone river: a manufacturing district of glass and metal recycling workshops and the riverine harbor of Rusellae, in use from the late 1st to late 5th century AD.
Spomenik
A spomenik is an abstract, high-modernist memorial built in socialist Yugoslavia between 1945 and 1991 to commemorate Partisan fighters and victims of fascist occupation, with thousands since vandalized or destroyed.
SPONASTRIME dysplasia
SPONASTRIME dysplasia, also called spondyloepimetaphyseal dysplasia Sponastrime type, is a rare autosomal recessive skeletal dysplasia caused by TONSL mutations, marked by short stature, midface hypoplasia, vertebral deformity, and metaphyseal striations.
Sponde
Sponde (Jupiter XXXVI) is a small retrograde irregular moon of Jupiter in the Pasiphae group, discovered in 2001 at Mauna Kea and named for one of the Horae.
Spondias
Spondias (mombins, hog plums, umbu, ambarella) is a genus of 18 Anacardiaceae fruit-tree species native to tropical America, Madagascar, and Asia, type genus of Spondioideae, cultivated for fruit and long used in traditional medicine.
Spondias dulcis
Spondias dulcis, also called ambarella, golden apple, or Polynesian plum (synonym Spondias cytherea), is an Anacardiaceae fruit tree native to E. Malesia to the Santa Cruz Islands, widely introduced across the tropics for its edible drupe.
Spondias mombin
Spondias mombin, yellow mombin, hog plum, jobo, or Brazilian cajá, is a tropical Anacardiaceae fruit tree native from Mexico to South America, with yellow edible drupes used fresh, processed, and in traditional medicine; IUCN Least Concern.
Spondylectomy
Spondylectomy is a spine surgical procedure that removes an entire affected vertebra, usually en bloc, to treat primary malignant or aggressive benign spinal tumors and selected metastases.
Spondyliosoma cantharus
Spondyliosoma cantharus, the black seabream (Sparus cantharus), is an eastern Atlantic and Mediterranean sparid fish, a protogynous hermaphrodite food fish reaching 60 cm, IUCN Least Concern, with regionally structured populations.
Spondylo-megaepiphyseal-metaphyseal dysplasia
Spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD, OMIM 613330) is an ultra-rare autosomal recessive skeletal dysplasia caused by NKX3-2 loss-of-function mutations on 4p15.33, marked by delayed vertebral ossification, giant epiphyses, and pseudoepiphyses.
Spondylo-ocular syndrome
Spondylo-ocular syndrome (SOS, OMIM 605822), also called spondyloocular syndrome, is an autosomal recessive XYLT2-related skeletal and ocular disorder with osteoporosis, platyspondyly, cataract, retinal detachment, hearing loss, and cardiac defects.
Spondyloarthropathy
Spondyloarthropathy (spondyloarthritis, SpA) is a family of inflammatory rheumatic diseases affecting the spine and peripheral joints, including ankylosing spondylitis, psoriatic arthritis, and reactive arthritis, linked to HLA-B27, uveitis, psoriasis, and IBD.
Spondylocarpotarsal synostosis
Spondylocarpotarsal synostosis, also called congenital synspondylism, is a rare skeletal dysplasia in which fusion of spine, wrist, and ankle bones causes short stature and scoliosis; it is usually caused by FLNB gene mutations.
Spondylodysplastic Ehlers-Danlos syndrome
Spondylodysplastic Ehlers-Danlos syndrome (spEDS, spondylodysplastic EDS) is an ultra-rare autosomal recessive connective tissue disorder with B4GALT7, B3GALT6, or SLC39A13 subtypes, causing short stature, hypotonia, joint hypermobility, and skeletal anomalies.
Spondyloenchondrodysplasia
Spondyloenchondrodysplasia (SPENCD, SPENCDI) is a very rare autosomal recessive skeletal dysplasia caused by biallelic ACP5 mutations, causing platyspondyly, enchondromas, short stature, spasticity, cerebral calcifications, and autoimmunity.
Spondyloepimetaphyseal dysplasia with joint laxity, Beighton type
Spondyloepimetaphyseal dysplasia with joint laxity, Beighton type, also called SEMD-JL1, is a rare autosomal recessive skeletal disorder caused by B3GALT6 mutations, producing short stature, joint dislocations, and progressive kyphoscoliosis.
Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type
Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type (SEMDJL2) is a rare autosomal dominant skeletal dysplasia with short stature, multiple joint dislocations, and slender fingers and toes.
Spondyloepiphyseal dysplasia congenita
Spondyloepiphyseal dysplasia congenita (SEDC, SED congenita) is a rare COL2A1-related type II collagenopathy causing disproportionate short-trunk short stature, myopia, retinal detachment, hearing loss, and cervical instability, usually autosomal dominant and apparent at birth.
Spondyloepiphyseal dysplasia tarda
Spondyloepiphyseal dysplasia tarda (SEDT, SEDL, OMIM 313400) is a rare X-linked recessive skeletal dysplasia caused by TRAPPC2 mutations, causing late-onset short-trunk short stature, platyspondyly with vertebral humping, and precocious hip osteoarthritis in males.
Spondyloepiphyseal dysplasia, Kimberley type
Spondyloepiphyseal dysplasia, Kimberley type (SEDK, OMIM 608361) is a rare mild autosomal dominant skeletal dysplasia from ACAN (aggrecan) mutations, causing short stature, stocky build, and early-onset osteoarthritis of weight-bearing joints.
Spondylolisthesis
Spondylolisthesis: forward or other translation of one vertebra on another, graded I–V by the Meyerding system. Common forms are isthmic (pars defect, L5–S1) and degenerative (L4–L5, women over 65); nonoperative care is first-line.
Spondylolysis
Spondylolysis, a stress fracture defect of the pars interarticularis, usually at L5, is a leading cause of low back pain in adolescent athletes; treated first with bracing and physical therapy, surgery if refractory.
Spondylometaphyseal dysplasia-cone-rod dystrophy syndrome
Spondylometaphyseal dysplasia-cone-rod dystrophy syndrome (SMD-CRD, OMIM 608940) is a rare autosomal recessive disorder caused by PCYT1A mutations, combining platyspondyly, metaphyseal irregularity, severe short stature, and progressive cone-rod retinal dystrophy.
Spondylometaphyseal dysplasia, Kozlowski type
Spondylometaphyseal dysplasia, Kozlowski type (SMDK, OMIM 184252) is a rare autosomal dominant TRPV4-related skeletal dysplasia with short-trunk short stature, platyspondyly, kyphoscoliosis, and proximal femoral metaphyseal changes.
Spondylometaphyseal dysplasia, Sedaghatian type
Spondylometaphyseal dysplasia, Sedaghatian type (SSMD, OMIM 250220), also called lethal metaphyseal dysplasia, is a neonatal-lethal autosomal recessive GPX4-related skeletal dysplasia with platyspondyly, cardiac conduction defects, and CNS malformations.
Spondylosis
Spondylosis, or spinal osteoarthritis, is age-related degeneration of the spine's discs and facet joints, mainly cervical and lumbar; about 90% of adults over 60 have it, often without symptoms.