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Spycatcher

Spycatcher: The Candid Autobiography of a Senior Intelligence Officer, 1987 memoir by ex-MI5 officer Peter Wright with Paul Greengrass. Thatcher's government tried to ban it; published in Australia and the US, it sold about 2 million copies and reshaped British secrecy law.

Spydeberg

Spydeberg: former municipality in Østfold, Norway (municipal number 0123), on the west side of Glomma; merged into Indre Østfold in 2020; site of the 1814 Spydeberg Council at the parsonage.

SPYDER

SPYDER (Surface-to-Air PYthon and DERby) is a mobile short-to-medium-range air defense system by Israel's Rafael, firing Python-5 and Derby missiles from truck-mounted launchers against aircraft, helicopters, UAVs, and cruise missiles.

Spyder (స్పైడర్) (film)

Spyder (స్పైడర్), a 2017 Telugu–Tamil bilingual action thriller by A. R. Murugadoss starring Mahesh Babu, Rakul Preet Singh, and S. J. Suryah; released 27 September 2017; streams on ZEE5.

Spyfall (Doctor Who)

Spyfall is the two-part Doctor Who story (also called Spyfall Part One and Part Two) opening series 12 on BBC One in January 2020, written by Chris Chibnall, starring Jodie Whittaker and featuring Sacha Dhawan's Master, the Kasaavin, and the Timeless Child revelation.

Spyglass Media Group

Spyglass Media Group, LLC (formerly Lantern Entertainment LLC) is an American independent film and TV company founded March 13, 2019 by Gary Barber and Lantern co-presidents, holding the Weinstein Company library, Scream and Hellraiser franchises, and Project Runway, with Warner Bros., Eagle Pictures, and Cineworld as investors.

SpyGlass Pharma

SpyGlass Pharma is an ophthalmic biopharmaceutical company, founded in 2019 by Malik Kahook and Glenn Sussman, developing an implant that delivers three years of glaucoma medication.

SPYK04

SPYK04 is Chugai-discovered oral RAF-MEK molecular glue, a MEK1/2 inhibitor for MAPK-altered solid tumors; Phase I NCT04511845 showed 8.7% ORR, and InxMed licensed it worldwide in 2026.

Spyker Cars

Spyker Cars is a Dutch manufacturer of hand-built sports cars, founded in 1999 by Victor Muller to revive the Spyker marque, and known for its limited-production C8 series.

Spyre Therapeutics

Spyre Therapeutics, also known as Aeglea BioTherapeutics, is a clinical-stage biotechnology company based in Waltham, Massachusetts. It develops long-acting antibodies for IBD, including SPY001, SPY002, and SPY003.

Spyridon G.A. Alivisatos

Spyridon G.A. Alivisatos, also published as S.G.A. Alivisatos, was a biochemist and neuropharmacologist trained at McGill University who studied how serotonin binds at receptors in the brain.

Spyridon Louis (Σπυρίδων Λούης)

Spyridon Louis (Σπυρίδων Λούης), Greek water seller from Marousi, won the first Olympic marathon on 10 April 1896 in 2:58.50 over 40 km; died March 1940.

Spyridon Trikoupis

Spyridon Trikoupis (Σπυρίδων Τρικούπης, 1788–1873) was a Greek statesman, diplomat, and historian who served as minister and ambassador and wrote the four-volume History of the Greek Revolution.

Spyro

Spyro is a video game franchise starring a small purple dragon, beginning with Spyro the Dragon (1998) by Insomniac Games on PlayStation. Key entries: original trilogy, Skylanders (2011), Spyro Reignited Trilogy (2018, 11 million copies), and Spyro: A Realm Beyond (Spring 2027).

Spyro 2: Ripto's Rage!

Spyro 2: Ripto's Rage! (Gateway to Glimmer in Europe) is Insomniac Games' 1999 PlayStation 3D platformer, set in Avalar against the wizard Ripto, with Talisman/Orb progression, new abilities, and a 2018 Reignited Trilogy remaster.

Spyro Gyra

Spyro Gyra: American jazz fusion and smooth jazz band founded by Jay Beckenstein and Jeremy Wall in Buffalo, New York, in 1974; named after a misspelled algae genus; breakthrough 1979 platinum album Morning Dance with a #1 AC hit.

Spyro Reignited Trilogy

Spyro Reignited Trilogy is a 2018 Toys for Bob/Activision remake of the first three Spyro PlayStation games, released November 13, 2018 on PS4 and Xbox One, later Switch and PC; Metascore 83, 11 million copies sold.

Spyro the Dragon

Spyro the Dragon is a 1998 PlayStation 3D platformer by Insomniac Games, published by SCEA, starring a purple dragon who charges, glides, and flames to free crystallized dragons from Gnasty Gnorc; remastered in the 11-million-selling Reignited Trilogy.

Spyro: A Realm Beyond

Spyro: A Realm Beyond is an upcoming Toys for Bob platform game announced June 7, 2026 at the Xbox Games Showcase, releasing Spring 2027 on Xbox, PS5, Steam, and Switch 2, with free dragon flight and the Scavs as antagonists.

Spyro: Enter the Dragonfly

Spyro: Enter the Dragonfly is a 2002 3D platformer, the fourth Spyro game and first on PS2 and GameCube, developed by Check Six and Equinoxe. Ripto steals 70 dragonflies; the rushed, buggy release scored 56 on Metacritic.

Spyro: Year of the Dragon

Spyro: Year of the Dragon (2000, PlayStation) is Insomniac Games' third Spyro platformer, published by Sony. Spyro recovers 150 stolen dragon eggs from the Sorceress with playable critters Sheila, Bentley, Sergeant Byrd, and Agent 9; highest-rated Spyro at 90.59%.

Spyros Artavanis-Tsakonas

Spyros Artavanis-Tsakonas is a Greek molecular biologist known for deciphering the Notch signaling pathway, a professor emeritus at Harvard Medical School and the Collège de France.

Spyros Ν. Pandis

Spyros N. Pandis (Σπύρος Ν. Πάνδης) is a Greek atmospheric scientist and chemical engineer, a professor at the University of Patras known for work on organic aerosols.

Spytihněv I of Bohemia

Spytihněv I was Duke of Bohemia from 894 to 915, the second documented Přemyslid ruler, who detached Bohemia from Great Moravia and founded Prague Castle.

Spyware

Spyware, also called surveillance software, is malware secretly installed to gather information without the user's knowledge, ranging from phone stalkerware to government tools like Pegasus.

Sq-1

Sq-1 (CVCL_4900, RRID:CVCL_4900) is a human lung squamous cell carcinoma cancer cell line from a Japanese male, carrying EGFR L858R (in 10% of cells) and a TP53 splice donor mutation, distributed as RCB1905 and TKG 0301.

SQ3R

SQ3R (Survey, Question, Read, Recite, Review) is Francis P. Robinson's 1946 five-step textbook reading and study method, widely taught but with little direct empirical support; its Recite and Review steps carry its evidence-based value.

Sqills

Sqills is a Dutch rail software company based in Enschede, founded in 2002, whose S3 Passenger platform provides cloud-based reservation and ticketing software; Siemens Mobility acquired it in 2021 for about $650 million.

SQL

SQL, or Structured Query Language, is the standard language for defining, querying, and controlling data in relational databases, developed at IBM in 1974 and standardized by ISO and ANSI.

SQL injection

SQL injection (SQLIA), also known as Structured Query Language injection, is a code injection attack where user input is interpreted as SQL code rather than data, letting attackers extract or alter database contents.