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DIABLO (gene)
DIABLO (SMAC) is a human chromosome 12 gene encoding a mitochondrial pro-apoptotic protein that binds IAPs via its AVPI motif to free caspases; discovered in 2000, linked to DFNA64 deafness, and the basis of Smac-mimetic cancer drugs.
Diablo (series)
Diablo is an action role-playing game franchise by Blizzard Entertainment, set in the dark fantasy world of Sanctuary and known for demon-slaying combat and randomly generated loot, beginning in 1996.
Diablo (video game)
Diablo (1996) is Blizzard North's action RPG, released December 31, 1996, in which heroes descend 16 randomly generated dungeon levels beneath Tristram to kill the Lord of Terror. It debuted Battle.net, three classes, random loot, and founded the action-RPG genre.
Diablo Canyon Power Plant
Diablo Canyon Power Plant, also known as Diablo Canyon Nuclear Power Plant, is California's last operating nuclear power plant, run by PG&E on the coast of San Luis Obispo County.
Diablo Cody
Diablo Cody (Brook Maurio, née Busey, born 1978) is an American screenwriter and author who won the 2008 Academy Award for her debut script Juno and also wrote Jennifer's Body, Young Adult, United States of Tara, and Jagged Little Pill.
Diablo Guardián
Diablo Guardián, Xavier Velasco's 2003 Premio Alfaguara-winning novel about Violetta, a Mexican teen who flees to New York with stolen money, and its 2018 Amazon Prime Video series, the platform's first Mexican original.
Diablo II
Diablo II is an action role-playing game developed by Blizzard North and released in 2000, a sequel to Diablo whose skill trees and loot system shaped later action RPGs.
Diablo II: Resurrected
Diablo II: Resurrected is Blizzard's 2021 remaster of Diablo II (2000) and Lord of Destruction, made with Vicarious Visions, released on PC and consoles with 4K visuals, legacy graphics toggle, cross-progression, and later the 2026 Reign of the Warlock DLC adding the first new class in 25 years.
Diablo III
Diablo III, also known as Diablo 3, is a 2012 action role-playing game by Blizzard Entertainment in which heroes fight demons and collect randomized loot in Sanctuary.
Diablo III: Reaper of Souls
Diablo III: Reaper of Souls (Reaper of Souls) is Blizzard's first expansion to Diablo III, released March 25, 2014 on PC and August 2014 on consoles as Ultimate Evil Edition, adding the Crusader class, Act V, level 70 cap, Adventure Mode, and Nephalem Rifts.
Diablo Immortal
Diablo Immortal: free-to-play action MMORPG by Blizzard and NetEase, set between Diablo II and Diablo III; launched June 2022 on mobile and PC; known for pay-to-win gem monetization and $100M early revenue.
Diablo IV
Diablo IV (Diablo 4) is Blizzard Entertainment's 2023 open-world action RPG, the fourth mainline Diablo game, with five launch classes, the Vessel of Hatred (2024) and Lord of Hatred (2026) expansions, and a Metacritic PC score of 86.
Diablo IV: Lord of Hatred
Diablo IV: Lord of Hatred is Blizzard's second Diablo IV expansion, released April 28, 2026. It adds the Skovos region, Paladin and Warlock classes, a free skill tree rework removing passives, and concludes the Mephisto storyline.
Diablo IV: Vessel of Hatred
Diablo IV: Vessel of Hatred is Blizzard's first Diablo IV expansion, released October 7, 2024. It adds the Nahantu region, Spiritborn class, Mercenaries, Runewords, and Dark Citadel; Metacritic PC 84, OpenCritic 86.
Diablos Rojos del México
Diablos Rojos del México: Mexico City professional baseball team founded 1940 in the Liga Mexicana de Béisbol; record 18 championships, plays at Estadio Alfredo Harp Helú since 2019, back-to-back 2024-2025 titles.
Diabolic (film)
Diabolic is a 2025 Australian religious horror film directed by Daniel J. Phillips, starring Elizabeth Cullen, John Kim, and Mia Challis. Inspired by Ticia Madsen's Mormon church experiences, it won Best Australian Feature at Monster Fest and released in the US in February 2026.
Diabolical Masquerade
Diabolical Masquerade was the Swedish one-man avant-garde black metal project of Katatonia guitarist Anders "Blakkheim" Nyström, active in Stockholm from 1993 until 2004 and releasing four albums.
Diabolik Lovers (ディアボリックラヴァーズ)
Diabolik Lovers (ディアボリックラヴァーズ) is a Rejet and Otomate media mix franchise of otome games, drama CDs, and anime about heroine Yui Komori and sadistic vampire brothers, beginning as a 2011 situation CD with the first game in 2012.
Diabolik: Ginko Attacks!
Diabolik: Ginko Attacks! (Diabolik - Ginko all'attacco!) is a 2022 Italian crime thriller by the Manetti Bros., the second film of their Diabolik trilogy, adapting comic issue no. 16 (1964), with Giacomo Gianniotti replacing Luca Marinelli and Monica Bellucci as Altea.
Diabolik: Who Are You?
Diabolik: Who Are You? (Diabolik - Chi sei?) is a 2023 Italian crime film by the Manetti Bros., the final chapter of their Diabolik trilogy, based on the 1968 comic issue no. 107, starring Giacomo Gianniotti, released in Italy on 30 November 2023.
Diabolo (空竹)
Diabolo (空竹, kongzhu), the Chinese yo-yo: an hourglass spool spun on a string between two handsticks. Originated in Ming China, patented in rubber by Phillippart 1905; fixed vs bearing axles, string climb, heritage status, world contests.
Diabolus in Musica
Diabolus in Musica is Slayer's eighth studio album (1998, Columbia), Latin for "the devil in music" after the tritone. Largely written by Jeff Hanneman, groove-based and down-tuned, it sold 46,000 first week, peaked at No. 31 on the Billboard 200, and divided fans over its nu metal debate.
Diabrotica speciosa
Diabrotica speciosa (vaquita de San Antonio, cucurbit beetle), a South American chrysomelid leaf beetle pest of maize, potato, peanut, and cucurbits; EPPO A1 quarantine pest absent from Europe.
Diabrotica undecimpunctata
Diabrotica undecimpunctata, the spotted cucumber beetle (southern corn rootworm, subspecies howardi; western spotted cucumber beetle, subsp. undecimpunctata), is a polyphagous North American chrysomelid pest of cucurbits, corn, and beans that vectors bacterial wilt and mosaic viruses and is an EPPO A1 quarantine pest.
Diabrotica virgifera
Diabrotica virgifera (western corn rootworm), a North American chrysomelid beetle and major maize pest; subspecies virgifera and zeae; invasive in Europe since 1992; managed by crop rotation.
Diacerein
Diacerein (diacetylrhein), an anthraquinone IL-1beta inhibitor synthesized in 1980, treats hip and knee osteoarthritis symptoms; EU-restricted in 2014 for diarrhoea and liver risks, not marketed in the US.
Diacetone alcohol
Diacetone alcohol, or 4-hydroxy-4-methyl-2-pentanone, is a clear, water-miscible beta-hydroxy ketone solvent made by condensing two acetone molecules. A slow-evaporating solvent used mainly in paints and coatings, it is also an intermediate for mesityl oxide.
Diacetyl
Diacetyl (butane-2,3-dione) is a volatile diketone with an intense buttery aroma that occurs naturally in butter, beer, wine, and coffee and is used as a flavoring agent.
Diaclone
Diaclone is a Japanese transforming and combining robot toy series created by Takara in 1980, whose Car Robots toys Hasbro rebranded as Transformers in 1984; Takara Tomy relaunched it in 2016.
Diacritic
Diacritic (diacritical mark): a sign added above, below, through, or beside a base letter to modify pronunciation, stress, tone, or meaning, as in café or naïve; encoded in Unicode as combining marks (U+0300–U+036F) or precomposed letters.