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Distal muscle weakness-foot deformity-elevated sorbitol level-hereditary motor neuropathy

SORD deficiency (ORPHA:700508, sorbitol dehydrogenase deficiency) is an autosomal recessive hereditary motor neuropathy caused by SORD gene variants, causing sorbitol accumulation, distal weakness, foot deformity, and potential aldose reductase inhibitor treatment.

Distal muscular dystrophy

Distal muscular dystrophy (distal myopathy) is a group of rare genetic muscle diseases with adult-onset weakness starting in hands, feet, and lower legs; nearly 20 genetically defined entities, mostly sarcomere protein genes, fewer than 1 in 100,000 affected.

Distal myopathy with anterior tibial onset

Distal myopathy with anterior tibial onset (DMAT, OMIM 606768) is a rare autosomal recessive dysferlinopathy caused by DYSF mutations, starting with anterior tibial weakness in the second or third decade and leading to wheelchair dependence 11 to 22 years from onset.

Distal pancreatectomy

Distal pancreatectomy is an operation removing the pancreas body and tail to the left of the mesenteric vein, usually with the spleen, accounting for over 20% of pancreatic resections.

Distal radius fracture

Distal radius fracture (broken wrist): break of the radius near the wrist, about 16% of all fractures; Colles, Smith, and Barton patterns; treated by casting or surgery, with comparable long-term outcomes in the elderly.

Oct 20, 2026

Distal renal tubular acidosis

Distal renal tubular acidosis (type 1 RTA, classic RTA): a rare genetic or acquired kidney tubule disorder causing hyperchloremic metabolic acidosis, hypokalemia, nephrocalcinosis, and stones; treated with alkali therapy.

Distal tail protein, C-terminal domain

Distal tail protein, C-terminal domain (Dit CTD, InterPro IPR048272): the galectin-like beta-sandwich domain of phage Dit that forms a sixfold crown binding Tal and receptor binding proteins in siphovirus tail tips.

Distal tail protein, N-terminal domain

Distal tail protein N-terminal domain (Dit NTD): tail tube-fold module of tailed dsDNA phages whose six copies form the hexameric baseplate hub ring linking tail tube to Tal and host-recognition proteins.

Distalmotion

Distalmotion is a Swiss medical robotics company founded in 2012 as an EPFL spin-off, headquartered in Lausanne, that develops DEXTER, a soft-tissue surgical robot for outpatient surgery centers.

Distance

Distance is the scalar length of the path actually traveled between two positions; unlike displacement, it has no direction and depends on the path taken.

Oct 3, 2026

Distance (DISTANCE) (2001 film)

Distance (ディスタンス) is Hirokazu Kore-eda's 2001 Japanese drama about relatives of cult mass-murderers, In Competition at Cannes 2001, 132 minutes, starring ARATA, Iseya, Terajima, Natsukawa, and Asano.

Distance (Hikaru Utada album)

Distance is Hikaru Utada's second studio album, released March 28, 2001 on Toshiba EMI's Eastworld label (TOCT-24601); it set Japan's all-time first-week sales record of 3.00 million copies and ranks fourth in Oricon history.

Sep 19, 2026

Distance (musician)

Distance is the stage name of Greg Sanders, a British dubstep producer and DJ from London, active since 2003 and known as an originator of the original dubstep sound.

Distance correlation

Distance correlation is a measure of statistical dependence between two random vectors, introduced by Székely, Rizzo, and Bakirov in 2007, that is zero if and only if they are independent.

Distance counseling

Distance counseling, also known as telepsychology or telemental health, is the delivery of psychotherapy and counseling remotely by phone, video, email, chat, or text, which became mainstream during the COVID-19 pandemic.

Distance education

Distance education: formal, institution-based learning where teachers and learners are separated by space or time, delivered via correspondence, broadcast, telecommunications, or online platforms; distinct from blended and open learning.

Distance from a point to a line

The distance from a point to a line, also called the perpendicular distance, is the length of the shortest segment joining the point to the line, minimized by the perpendicular.

Distance geometry

Distance geometry is a mathematical method that determines possible three-dimensional structures of molecules from a set of distances between pairs of points, mainly from NMR data.

Distance matrix

A distance matrix is a square matrix recording the pairwise distances between elements of a finite set, with a symmetric, zero-diagonal form when the distance is a metric.

Distance measuring equipment

Distance measuring equipment (DME) is an aviation radio navigation system that measures the distance between an aircraft and a ground station by timing radio pulses.

Distance modulus

The distance modulus is the difference between an astronomical object's apparent and absolute magnitude, μ = m − M, which provides a direct measure of its distance.

Distance redshift relation

The distance redshift relation links an object's redshift, the stretching of its light by cosmic expansion, to its distance; measured with supernovae, it revealed the accelerating expansion driven by dark energy.

Distance relay

A distance relay is a protective relay, designated ANSI device 21, that measures voltage-to-current ratio to detect and locate faults within a set electrical distance of a power line.

Distance sampling

Distance sampling is a suite of survey methods, built on line and point transects, that estimates animal or plant density and abundance from measured distances to detected individuals.

Distance transform

The distance transform assigns each point of a binary image the distance to the nearest object pixel, under metrics like Euclidean or city-block, supporting skeletonization, segmentation, and path planning.

Distance-regular graph

A distance-regular graph is a connected graph where, for any two vertices at a given distance, the counts of neighbors at each distance depend only on that distance.

Distance-vector routing protocol

A distance-vector routing protocol is a distributed routing protocol in which each router knows only the distance and next hop to each destination, as reported by its immediate neighbors.

Distancing effect

Distancing effect (Verfremdungseffekt, alienation effect) is Bertolt Brecht's epic-theatre technique of anti-illusive devices, songs, placards, and detached acting, coined after Mei Lanfang's 1935 Moscow performance, that keeps spectators critical rather than empathetic.

Distant retrograde orbit

A distant retrograde orbit, also known as a quasi-satellite orbit (QSO), is a stable orbit around a body like the Moon, first studied by John Jackson in 1913.