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EF-Ts

EF-Ts (elongation factor thermo stable, tsf gene) is the bacterial guanine nucleotide exchange factor that reactivates EF-Tu by exchanging GDP for GTP, accelerating GDP release 6 × 10^4-fold; eukaryotic counterpart EF1B.

EF-Tu

EF-Tu (EF1A), bacterial GTPase elongation factor delivering aminoacyl-tRNA to the ribosome as aa-tRNA·EF-Tu·GTP; GTP hydrolysis triggered by His84-SRL contact; key to translation accuracy and the most abundant E. coli protein.

EF5 drought

The EF5 drought, also called the EF5 gap, was the period from 2013 to 2025 with no EF5-rated US tornadoes, the longest since records began in 1950.

Efacec

Efacec is a Portuguese manufacturer of transformers, switchgear, substation automation, railway solutions, and electric-vehicle chargers, founded in 1948 and headquartered in Porto, with operations in 87 countries.

Efalizumab

Efalizumab (Raptiva, anti-CD11a) was a humanized IgG1 monoclonal antibody for plaque psoriasis, FDA-approved 2003 and EU-authorized 2004, withdrawn from both markets in 2009 over progressive multifocal leukoencephalopathy risk.

Efaproxiral

Efaproxiral (RSR13, Efaproxyn) is a synthetic allosteric hemoglobin modifier that lowers oxygen affinity to sensitize hypoxic tumors to radiation. Developed by Allos Therapeutics for brain metastases; discontinued after phase III results.

Éfaté Island

Éfaté (Efate, Vaté) is Vanuatu's most populated island, third largest at about 900 km², in Shefa Province. It hosts the capital Port Vila, the Teouma Lapita cemetery (~3000 BP), and about 80% of national economic activity.

Efavirenz

Efavirenz, sold as Sustiva and Stocrin, is an NNRTI drug used to treat HIV type 1 infection, the first of its class approved as preferred first-line therapy.

Efbemalenograstim alfa

Efbemalenograstim alfa (F-627, Ryzneuta, efbemalenograstim alfa-vuxw) is a non-PEGylated Fc-fusion long-acting G-CSF, 20 mg once per chemotherapy cycle, FDA approved 2023 and EU approved 2024 for chemotherapy-induced neutropenia.

Efdalzâde Hamîdüddin Efendi

Efdalzâde Hamîdüddin Efendi, son of the scholar Efdalüddin, was the seventh Ottoman şeyhülislam, serving under Sultan Bayezid II from March 1496 until his death in February 1503.

Efdamrofusp alfa

Efdamrofusp alfa (IBI302) is a first-in-class bispecific VEGF and complement C3b/C4b fusion protein by Innovent Biologics for neovascular AMD; Phase 3 STAR met its endpoint in March 2026 with extended dosing.

Efe Ajagba

Efe Ajagba, 'The Silent Roller' (born 1994, Ughelli, Nigeria), Nigerian heavyweight boxer, 2016 Olympian, record 21-1-1 (15 KOs), based in Stafford, Texas, ranked in The Ring's heavyweight top 10, promoted by Zuffa Boxing.

Efecto Pasillo

Efecto Pasillo is a Spanish pop-rock band formed in 2007 in Gran Canaria, best known for "Pan y mantequilla", which topped the Los 40 chart in 2012.

EFEMP1

EFEMP1 (fibulin-3) is a 493-amino-acid extracellular matrix glycoprotein gene on chromosome 2p16.1; the recurrent R345W mutation causes Doyne honeycomb retinal dystrophy/Malattia Leventinese, with links to glaucoma, myopia, and AMD.

Efepoetin alfa

Efepoetin alfa (GC1113, GX-E2) is a long-acting recombinant human erythropoietin fused to a hybrid Fc for FcRn-mediated recycling, developed by Genexine for anemia of chronic kidney disease; phase 3 showed non-inferiority to methoxy polyethylene glycol-epoetin beta.

Efes Beverage Group

Efes Beverage Group is the beer and soft drinks business of Anadolu Efes, a Turkish company founded in 1969, brewing in 21 breweries across six countries and ranking as Europe's fifth-largest brewer.

Efes Pilsen Blues Festival (İstanbul Blues Festival)

The Efes Pilsen Blues Festival, also known as the İstanbul Blues Festival, was Turkey's longest-running music festival, an annual touring blues series organized by Pozitif from 1990 to 2012.

Effect of Hurricane Katrina on the Louisiana Superdome

During Hurricane Katrina in 2005, the Louisiana Superdome in New Orleans sheltered over 10,000 evacuees while its roof partially failed and its utilities broke down.

Effect of psychoactive drugs on animals

Effect of psychoactive drugs on animals: veterinary use of anxiolytics, antidepressants, and antipsychotics in pets and zoo animals, plus animal models of addiction and psychedelics, with species-specific pharmacokinetics and translational limits.

Effect of spaceflight on the human body

The effect of spaceflight on the human body is the set of physiological changes from weightlessness, radiation, and isolation, including bone loss and vision problems studied by NASA.

Effect of the 2004 Indian Ocean earthquake on Thailand

Effect of the 2004 Indian Ocean earthquake on Thailand: the 26 December 2004 Sumatra tsunami struck six Andaman-coast provinces, killing thousands, devastating fisheries and tourism, and prompting a national warning system.

Effect of the Gaza war on children in the Gaza Strip

Impact of the Gaza war (from 7 October 2023) on Gaza Strip children: over 64,000 killed or injured, repeated displacement averaging 8.1 times, famine, closed schools for 637,500 children, and widespread trauma per UNICEF and UN data.

Effect size

Effect size is a quantitative measure of how large a difference or relationship in a study is, reported in original units or standardized forms such as Cohen's d.

Effect system

An effect system is a static analysis, usually built into a type system, that tracks what side effects an expression may perform, such as I/O or exceptions.

Effective accelerationism

Effective accelerationism, abbreviated e/acc, is a techno-optimist movement begun on X in 2022 that argues powerful technology, especially AGI, should be advanced quickly rather than held back.

Effective altruism

Effective altruism is a philosophical and social movement that uses evidence and reasoning to find how best to help others, prioritizing global health, animal welfare, and reducing existential risks.

Effective climate sensitivity

Effective climate sensitivity (EffCS) is the warming response to doubled CO2 evaluated for evolving non-equilibrium conditions, allowing estimation from observations or models without waiting for full equilibrium.

Effective demand

Effective demand is the level of aggregate demand that governs firms' output and employment, defined by Keynes in his 1936 General Theory as demand at the intersection of aggregate demand and supply functions.

Effective descriptive set theory

Effective descriptive set theory is the lightface study of effective Borel, analytic, and co-analytic sets on recursive Polish spaces, merging classical descriptive set theory with Kleene's recursion theory.

Effective dose (pharmacology)

The effective dose in pharmacology is the amount of a drug that produces a defined therapeutic effect; the median effective dose (ED50) produces it in 50% of the population.