335 articles
Benign neoplasm of duodenum
Benign neoplasm of duodenum (ICD-11 2E92.2; ICD-10 D13.2): noncancerous duodenal tumors, mainly adenomas, lipomas, leiomyomas, and Brunner gland lesions; 10–20% of duodenal tumors, managed by endoscopic resection.
Bezoar
Bezoar: an indigestible mass (phytobezoar, trichobezoar, diospyrobezoar) in the gastrointestinal tract, once prized as an antidote; now treated by Coca-Cola dissolution, endoscopy, or surgery.
Bile acid malabsorption
Bile acid malabsorption (BAM, bile acid diarrhea/BAD): chronic watery diarrhea from excess colonic bile acids due to ileal reabsorption failure or excess synthesis; types 1–3; diagnosed by SeHCAT, serum C4, FGF19; treated with bile acid sequestrants.
Black hairy tongue
Hypertrophy of tongue papillae (ICD-11 DA03.4), also called hairy tongue or black hairy tongue (lingua villosa nigra): benign elongation of filiform papillae from delayed desquamation, linked to smoking, antibiotics, and poor oral hygiene.
Bloating
Bloating: uncomfortable abdominal fullness or pressure, distinct from visible distension. Common causes include gut gas from FODMAPs, constipation, IBS, SIBO, and visceral hypersensitivity; low FODMAP diet is the best-supported therapy.
Blood in stool
Blood in stool (rectal bleeding, hematochezia, melena): visible GI bleeding from hemorrhoids, fissures, diverticula, polyps, IBD, or colorectal cancer; color and pattern hint at the bleeding source.
Bowel obstruction
Bowel obstruction, also called intestinal obstruction, is a mechanical blockage of intestinal contents, usually from adhesions, hernias, or tumors; strangulation threatens bowel viability, and treatment combines resuscitation, decompression, and selective surgery.
Bristol stool scale
Bristol stool scale (Bristol Stool Form Scale, BSFS): seven-type medical tool classifying human feces from type 1 hard lumps to type 7 watery diarrhea; types 3-5 normal; developed at Bristol Royal Infirmary, validated for transit time by Lewis and Heaton in 1997.
Cannabinoid hyperemesis syndrome
Cannabinoid hyperemesis syndrome (CHS), cannabis hyperemesis: cyclic vomiting, abdominal pain, and compulsive hot bathing from chronic cannabis use, relieved by cessation; treated with haloperidol or capsaicin.
Cap polyposis
Cap polyposis is a rare, benign colorectal condition in which inflammatory polyps covered by a white cap arise mainly in the rectum, causing rectal bleeding and altered bowel habits.
Change in bowel habit
Change in bowel habit (altered bowel habit): any alteration in stool frequency, consistency, or form; ICD-11 ME05, ICD-10 R19.4. Cardinal IBS symptom and colorectal cancer red flag prompting FIT and calprotectin testing.
Charles Osborne (farmer)
Charles Osborne (1893 or 1894–May 1991), American Iowa farmer, holds the Guinness record for the longest hiccup attack: 68 years, 1922 to February 1990, 20–40 hiccups per minute, about 430 million hiccups, after a 1922 hog-lifting accident.
Chemical gastritis
Chemical gastritis, also called reactive gastritis, reactive gastropathy, or type C gastritis, is stomach lining injury from chemical irritants such as NSAIDs, alcohol, and bile, with minimal inflammation; it affects about 15 percent of people in the United States.
Chemical oesophagitis
Chemical oesophagitis (caustic or corrosive oesophagitis, ICD-11 DA24.20) is esophageal inflammation from ingested acids or alkalis. Alkalis injure the esophagus most, strictures form in about 25%, endoscopy within 24 hours grades injury.
Chronic appendicitis
Chronic appendicitis (ICD-11 DB10.1; grumbling or recurrent appendicitis) is a non-acute, prolonged inflammation of the appendix causing persistent right lower quadrant pain, diagnosed by history, deep palpation, histology, and relief after appendectomy.
Chronic diarrhea due to glucoamylase deficiency
Chronic diarrhea due to glucoamylase deficiency, also called maltase-glucoamylase deficiency (ORPHA:103907, ICD-11 5C61.1), is a rare intestinal disease of infancy or childhood: primary small-intestinal glucoamylase deficiency impairs starch absorption, causing chronic diarrhea with normal pancreatic amylase and normal mucosal histology.
Chronic enteropathy associated with SLCO2A1 gene
Chronic enteropathy associated with SLCO2A1 gene (CEAS), formerly CNSU, is a rare autosomal recessive small-intestinal ulcer disease from SLCO2A1 prostaglandin transporter mutations, mimicking Crohn's disease, with female predominance, anemia, and ileal ulcers.
Chronic intestinal failure
Chronic intestinal failure (CIF, type 3 intestinal failure): persistent loss of gut absorptive function requiring long-term intravenous supplementation, usually home parenteral nutrition. Main cause short bowel syndrome; treatments include teduglutide and intestinal transplantation.
Chronic intestinal pseudoobstruction syndrome
Chronic intestinal pseudoobstruction syndrome (CIPO, CIPS) is a rare severe gastrointestinal motility disorder mimicking mechanical bowel obstruction without occlusive lesion, treated with nutrition support, prokinetics, and sometimes transplant.
Chronic proliferative peritonitis
Chronic proliferative peritonitis (慢性増殖性腹膜炎), ICD-11 DC50.12, also called sclerosing encapsulating peritonitis: extensive peritoneal fibrosis from asbestos or CAPD, causing intestinal obstruction via massive adhesions; maps to ICD-10 K65.8.
Chylomicron retention disease
Chylomicron retention disease (Anderson disease, CMRD) is a rare autosomal recessive fat-malabsorption disorder caused by biallelic SAR1B mutations blocking COPII chylomicron secretion, presenting in infancy with failure to thrive, steatorrhea, and hypocholesterolemia with normal triglycerides.
Ciguatera fish poisoning
Ciguatera fish poisoning (CFP), ciguatera, is seafood poisoning from ciguatoxins made by Gambierdiscus dinoflagellates and concentrated in large reef fish; 10,000–50,000 cases yearly, temperature reversal hallmark, fatality under 0.1%.
Coeliac disease
Coeliac disease (celiac disease, gluten-sensitive enteropathy) is a chronic autoimmune disorder triggered by gluten in wheat, barley, and rye, damaging the small intestine in about 1% of people; treated with a lifelong gluten-free diet.
Colectomy
Colectomy is surgery removing part or all of the colon, also called colon resection or bowel resection. Types include hemicolectomy, proctocolectomy, and sigmoidectomy; done open, laparoscopically, or robotically for cancer, diverticulitis, and IBD.
Colitis
Colitis is inflammation of the colon (large intestine), with infectious, ischemic, microscopic, radiation, and IBD forms such as ulcerative colitis and Crohn's disease; symptoms include bloody diarrhea, and treatment depends on cause.
Collagenous colitis
Collagenous colitis, a subtype of microscopic colitis first named by Lindström in 1976, causes chronic watery non-bloody diarrhea with a normal-looking colon; diagnosis needs biopsies showing a subepithelial collagen band ≥10 μm, and budesonide is first-line therapy.
Colonic abscess
Colonic abscess (ICD-11 DB36.0), a localized pus collection in or near the colon, usually from perforated diverticulitis, sometimes colon cancer; treated with antibiotics, plus percutaneous drainage when 3 cm or larger.
Colonic atresia
Colonic atresia, also called large intestinal atresia, is a rare congenital blockage or absence of part of the colon, the rarest intestinal atresia type, occurring in roughly 1 in 10,000 to 66,000 births and treated surgically.
Congenital antral web
Congenital antral web (prepyloric diaphragm, gastric antral web): a rare 2–4 mm mucosal membrane 1–7 cm proximal to the pylorus causing gastric outlet obstruction, presenting with non-bilious vomiting and failure to thrive, treated surgically or by endoscopic balloon dilation.
Congenital chloride diarrhea
Congenital chloride diarrhea (Darrow-Gamble syndrome, CLD/CCD) is a rare autosomal recessive SLC26A3 disorder causing prenatal-onset watery diarrhea with fecal chloride over 90 mmol/L, hypochloremic hypokalemic metabolic alkalosis, treated with lifelong NaCl/KCl replacement.