25,729 articles
Fenfluramine/phentermine
Fenfluramine/phentermine, or fen-phen, an off-label 1990s US weight-loss drug combination; fenfluramine (Pondimin) withdrawn September 1997 for serotonin-mediated valvular heart disease and pulmonary hypertension; phentermine remains available.
Fenofibrate
Fenofibrate, a PPARα-agonist fibrate prodrug of fenofibric acid, treats severe hypertriglyceridemia (TG ≥500 mg/dL) and primary hyperlipidemia; it lowers triglycerides 30–50% but did not reduce cardiovascular events in FIELD or ACCORD-Lipid.
Fenofibric acid
Fenofibric acid, active moiety of fenofibrate and a PPAR-alpha fibrate; marketed as Trilipix (2008) and Fibricor; adjunct to diet for hypercholesterolemia and hypertriglyceridemia, often with statins.
Fenoldopam
Fenoldopam, sold as Corlopam and known as SKF 82526, is a short-acting benzazepine drug given by intravenous infusion in hospitals to rapidly lower severe high blood pressure while preserving kidney blood flow.
Fenoprofen
Fenoprofen (brand Nalfon, Fenopron) is a propionic acid NSAID, C15H14O3, FDA-approved in 1976 as the calcium salt for rheumatoid arthritis, osteoarthritis, and mild to moderate pain, dosed up to 3,200 mg daily.
Fenoverine
Fenoverine, marketed as Spasmopriv, is a phenothiazine-derived antispasmodic drug that modulates calcium flow across gastrointestinal smooth muscle membranes to treat spasmodic conditions including irritable bowel syndrome.
Fenproporex
Fenproporex (femproporex), a racemic N-cyanoethyl amphetamine analogue anorectic developed in the 1960s, is metabolized to amphetamine, was never FDA-approved, is Schedule IV internationally, and was withdrawn in the EU and Brazil.
Fenspiride
Fenspiride (Pneumorel, Eurespal) is a spiro-compound anti-inflammatory bronchodilator for cough and respiratory disease, withdrawn from the EU market in 2019 over QT prolongation and torsades de pointes risk.
Fentanyl
Fentanyl is a synthetic opioid 50 to 100 times more potent than morphine, used for anesthesia and severe pain and the drug most often involved in U.S. overdose deaths.
Fenticonazole
Fenticonazole (Lomexin) is a topical and intravaginal imidazole antifungal, C24H20Cl2N2OS, CAS 72479-26-6, that inhibits fungal CYP51/ERG11 ergosterol synthesis and treats cutaneous dermatophytosis and vulvovaginal candidiasis.
Feodor Vassilyev (Фёдор Васильев)
Feodor Vassilyev (Фёдор Васильев), Russian peasant of Shuya (1707–c.1782); his first wife reportedly bore 69 children in 27 confinements, a Guinness record, and he 87 total by two wives, though unverified.
Feprazone
Feprazone (4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione), a phenylbutazone-related NSAID, ATC M01AX18/M02AA16, trialed in rheumatoid arthritis and osteoarthritis; withdrawn in Germany in 1984 over skin reactions and rat carcinogenicity.
Ferber method
Ferber method, also called graduated extinction or controlled crying, is a sleep training technique from Richard Ferber's 1985 book, using timed check-ins at increasing intervals to teach infants, typically from 6 months, to self-soothe.
Ferdinand Monoyer
Ferdinand Monoyer (1836–1912), French ophthalmologist of Strasbourg, Nancy, and Lyon; creator of the Monoyer eye chart, the 1875 decimal visual acuity notation, and the diopter unit, with his name hidden in the chart rows.
Ferdinand Sauerbruch
Ferdinand Sauerbruch (1875–1951) was a German surgeon whose negative-pressure chamber made open-chest operations possible, and one of the most influential surgeons of the first half of the twentieth century.
Fermagate
Fermagate (iron-magnesium hydroxycarbonate, ALPHAREN) is an investigational calcium-free oral phosphate binder with a hydrotalcite structure, developed by Ineos Healthcare for hyperphosphatemia in hemodialysis; phase 2 trials showed dose-dependent phosphate lowering, but phase 3 was stopped and it was never approved.
Ferric carboxymaltose
Ferric carboxymaltose (Injectafer, Ferinject) is an intravenous iron(III)-hydroxide carbohydrate complex approved in 2013 for iron deficiency anemia; notable for single high-dose dosing and FGF23-mediated hypophosphatemia risk, now under an FDA boxed warning.
Ferric derisomaltose
Ferric derisomaltose (iron isomaltoside 1000; Monoferric, Monofer) is an intravenous iron-carbohydrate complex for iron deficiency anemia, approved in Europe 2009 and the US in 2020, with low hypophosphatemia versus ferric carboxymaltose.
Ferric maltol
Ferric maltol (Feraccru, Accrufer) is an oral ferric iron-trimaltol complex for iron deficiency with or without anemia, approved in Europe and the US, dosed 30 mg twice daily, with gastrointestinal tolerability better than ferrous salts.
Ferric pyrophosphate
Ferric pyrophosphate (iron(III) diphosphate, Fe4(P2O7)3·xH2O, CAS 10058-44-3) is a water-insoluble iron salt used as a food iron fortificant, parenteral iron drug (ferric pyrophosphate citrate, FDA 2015), and EU low-risk molluscicide (2020/1018).
Ferriman–Gallwey score
The Ferriman–Gallwey score is a clinical scoring system that grades hair growth in nine androgen-sensitive body areas, quantifying hirsutism in women, mainly in PCOS diagnosis.
Ferritin nanocage drug delivery
Ferritin nanocage drug delivery uses ferritin, a hollow iron-storage protein that self-assembles into a 12 nm cage, to carry drugs, imaging agents, and therapeutic proteins into tumor cells.
Ferro-cerebro-cutaneous syndrome
Ferro-cerebro-cutaneous syndrome, also known as neurodevelopmental disorder with epilepsy and hemochromatosis, is a rare X-linked condition caused by PIGA gene mutations, with seizures, skin abnormalities, and body-wide iron overload beginning in infancy.
Ferrous bisglycinate
Ferrous bisglycinate (ferrous bis-glycine chelate, FeBC), an iron(II)-glycine amino acid chelate supplement and fortificant; GRAS (GRN 19, 1999); higher bioavailability and fewer GI side effects than iron salts, though clinical superiority is unproven.
Fertility awareness
Fertility awareness (natural family planning, periodic abstinence): identifying fertile days via cervical mucus, basal body temperature, or cycle tracking to achieve or avoid pregnancy; typical-use failure rates 2-23%, no STI protection.
Fertility Preservation
Fertility preservation (oncofertility) covers embryo, oocyte, sperm, and ovarian or testicular tissue cryopreservation before gonadotoxic cancer therapy or other fertility-threatening treatments; established versus experimental methods, counseling timing, and US insurance coverage distinguish it.
Ferumoxytol
Ferumoxytol, sold as Feraheme, is an intravenous iron replacement drug approved in the United States in 2009 for iron deficiency anemia in adults, especially with chronic kidney disease.
Fesoterodine
Fesoterodine, sold as Toviaz and as generics, is an antimuscarinic prodrug taken as a once-daily extended-release tablet for overactive bladder symptoms; its active metabolite is shared with tolterodine.
Fetal acetylcholine receptor antibody-related disorder
FARAD, fetal acetylcholine receptor antibody-related disorder, also called FARIS: maternal anti-fetal-AChR antibodies cross the placenta, causing arthrogryposis to persistent myopathy; preventable with pregnancy immunotherapy, salbutamol helps survivors.
Fetal akinesia deformation sequence
Fetal akinesia deformation sequence (FADS, Pena-Shokeir phenotype/syndrome type I): heterogeneous pattern of fetal akinesia, arthrogryposis, growth retardation, lung hypoplasia, and facial anomalies from any cause of absent fetal movement.