edgepedia

Human health and medicine

25,729 articles

Guillaume Duchenne de Boulogne

Guillaume Benjamin Amand Duchenne de Boulogne (1806–1875), French neurologist, pioneer of localized faradization, facial-expression photography, the Duchenne smile, muscle biopsy trocar, and Duchenne muscular dystrophy.

Guillermo Soberon

Guillermo Soberón (Guillermo Soberón Acevedo) was a Mexican physician and biochemist, rector of UNAM from 1973 to 1981 and Mexico's health minister from 1982 to 1988, who founded FUNSALUD.

Guizhi Mahuang Geban Tang

桂枝麻黄各半汤 (Guizhi Mahuang Geban Tang), a classical formula from Zhang Zhongjing's Shanghan Lun article 23, combining Guizhi Tang and Mahuang Tang 1:1 in reduced dose; a mild sweating formula used for surface-constraint patterns and widely for urticaria and itching skin diseases.

Guizhi Renshen Tang

桂枝人参汤 (Guizhi Renshen Decoction), a classical formula from the Shanghan Lun by Zhang Zhongjing: Lizhong Decoction plus cinnamon twig, for incessant diarrhea and epigastric fullness with unresolved exterior; now used for gastroenteritis, allergic rhinitis, and heart failure.

Guizhi Shaoyao Zhimu Decoction

Guizhi Shaoyao Zhimu Decoction (桂枝芍药知母汤, GSZD) is a nine-herb classical Chinese formula from Zhang Zhongjing's Jingui Yaolue for painful joint disease, used as adjunct therapy for rheumatoid and gouty arthritis.

Gulmakalanala Rasa

Gulmakalanala Rasa (गुल्मकालानल रस) is a mercury-based Ayurvedic formulation of the Rasa Shastra tradition, listed in the Ayurvedic Formulary of India for gulma, abdominal lumps.

Gumma (pathology)

Gumma (plural gummata): a soft, necrotic granuloma of tertiary syphilis caused by Treponema pallidum, most often in skin, bone, and liver, treated with benzathine penicillin G.

Gumokimab (ankylosing spondylitis indication)

Gumokimab (古莫奇单抗, AK111, 奇佑康) is Akeso's humanized IL-17 monoclonal antibody, approved in China for plaque psoriasis, whose ankylosing spondylitis phase III met all endpoints with an NMPA NDA under review.

Gums

Gums (gingivae) are the pink tissues surrounding the base of teeth, comprising marginal, attached, and interdental gingiva. Key diseases are reversible gingivitis and irreversible periodontitis, which affects about 4 in 10 U.S. adults over 30.

Gunshot wound

Gunshot wound: penetrating injury from a firearm projectile causing permanent cavitation and temporary cavitation. Also called GSW, ballistic trauma. US 2022: over 48,000 firearm deaths, about 132 daily; more than half suicides.

Gusacitinib

Gusacitinib (ASN002) is an oral dual pan-JAK/SYK inhibitor for chronic hand eczema, in phase 3 with Sanofi after Formation Bio acquired it from Asana BioSciences; phase 2 showed 69.5% mTLSS reduction at 80 mg.

Guselkumab

Guselkumab (Tremfya) is a fully human IgG1λ monoclonal antibody blocking the IL-23 p19 subunit, developed by Johnson & Johnson. First approved 2017 for plaque psoriasis; later indications include psoriatic arthritis, ulcerative colitis, Crohn's disease, and, from 2025, pediatric psoriasis and psoriatic arthritis.

Gusperimus

Gusperimus (deoxyspergualin, DSG, brand Spanidin) is a synthetic spergualin-derivative immunosuppressant binding Hsc70, studied for transplant rejection and Wegener's granulomatosis; EU orphan drug, marketing application withdrawn 2008, not FDA approved.

Gustatory hallucinations

Gustatory hallucinations, also called phantageusia, are tastes perceived without an oral stimulus; ICD-11 code MB27.21. They occur in epilepsy (parietal or rolandic operculum), psychosis (1-31% prevalence), and migraine.

Gustav Zander

Gustav Zander (1835–1920) was a Swedish physician who developed mechanotherapy, treating disease and injury with adjustable exercise machines, and opened his first institute in Stockholm in the 1860s.

Gustilo open fracture classification

Gustilo-Anderson classification: the standard 1976, 1984-modified grading of open fractures into Types I, II, IIIA, IIIB, IIIC by wound size, soft tissue damage, contamination, and vascular injury, guiding antibiotics and debridement.

GUSTO study

GUSTO (Growing Up in Singapore Towards healthy Outcomes) is Singapore's largest birth cohort study, recruiting about 1,450 pregnant women from 2009 to 2010 at KKH and NUH and following mother-child pairs to study early-life origins of metabolic and neurodevelopmental health.

Gut–brain axis

Gut–brain axis (microbiota–gut–brain axis): bidirectional communication network linking the central and enteric nervous systems and gut microbiota via vagal, HPA-axis, immune, and metabolite signaling; studied in IBS and neuropsychiatric disease.

Guttate psoriasis

Guttate psoriasis, also called drop-like psoriasis, is a psoriasis variant of small scattered teardrop-shaped scaly papules, often triggered by streptococcal throat infection in children and young adults, clearing in months or progressing to plaque psoriasis.

Guttmacher syndrome

Guttmacher syndrome (preaxial deficiency-postaxial polydactyly-hypospadias syndrome, ORPHA:2957, OMIM 176305) is an extremely rare autosomal dominant HOXA13 disorder with hypoplastic thumbs and halluces, hand polydactyly, uniphalangeal second toes without nails, and hypospadias, described in one family.

Guy M. McKhann

Guy M. McKhann (1932–2023) was an American neurologist who founded the Johns Hopkins Department of Neurology in 1969 and established the widely used McKhann Criteria for diagnosing Alzheimer's disease.

Guy's Hospital

Guy's Hospital, London SE1: NHS teaching hospital founded 1721 by Thomas Guy, opened 1725 for "incurables", endowed £219,499; now part of Guy's and St Thomas' NHS Foundation Trust with 400 beds and London's largest cancer care provider.

Guyin Jian

Guyin Jian (Gù yīn jiān, Decoction that Secures Yin) is a traditional Chinese medicine tonifying formula first recorded in Zhang Jiebin's Ming dynasty Jingyue Quanshu, nourishing liver and kidney yin.

GW501516

GW501516 (GW1516, Cardarine, Endurobol) is a potent PPARδ agonist developed by GSK and Ligand for metabolic disease, abandoned in 2007 over rodent carcinogenicity, and banned in sport by WADA since 2009.

Gwen Shamblin Lara

Gwen Shamblin Lara, known as Gwen Shamblin, was an American diet guru who founded the Weigh Down Workshop and Remnant Fellowship Church and died in a 2021 plane crash.

Gwendolyn Sowa

Gwendolyn Sowa is an American physician-scientist who chairs physical medicine and rehabilitation at the University of Pittsburgh, directs the UPMC Rehabilitation Institute, and was elected to the National Academy of Medicine in 2022.

Gym

Gym: a place or club for exercising with machines, weights, and other equipment, from the ancient Greek gymnasion to the modern commercial health club; covers history, health benefits, industry scale, and access barriers.

Gymshark

Gymshark is a British direct-to-consumer fitness apparel brand founded in 2012 by Ben Francis in a Birmingham garage, known for influencer marketing, its 2020 General Atlantic investment valuing it over £1 billion, and Regent Street retail.

GYN-ART study

GYN-ART (NCT06306170) is an observational, single-site study at IRCCS San Raffaele, Milan, evaluating toxicity and survival outcomes in 1,000 women with gynecologic cancer treated with IGRT, IMRT, or SBRT, distinct from the GynART 2011 EU funding effort.

Gynaecology

Gynaecology: medical and surgical care of disorders of the female reproductive system (ovaries, tubes, womb, cervix, vagina), paired with obstetrics; subspecialties include urogynaecology, reproductive medicine, colposcopy, and gynae-oncology.